Biplab. Dasgupta, et.al., AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development., Developmental cell, 2009, 16

http://rdf.ncbi.nlm.nih.gov/pubmed/19217427

Biplab. Dasgupta, et.al., AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development., Developmental cell, 2009, 16

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3838355

class

http://purl.org/net/cito/citesAsAuthority

• Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3838355

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• tremors_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0000745I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• decreased brain size_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0000774I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• abnormal cerebral cortex morphology_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0000788I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• abnormal dentate gyrus morphology_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0000812I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• abnormal cerebellum morphology_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0000849I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• absent cerebellar granule layer_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0000888I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
他20件を見る
• abnormal myelination_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0000920I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• decreased body weight_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0001262I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• abnormal optic nerve morphology_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0001330I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• ataxia_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0001393I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• seizures_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0002064I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• abnormal astrocyte morphology_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0002182I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• loss of hippocampal neurons_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0003240I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• astrocytosis_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0003354I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• abnormal neuronal precursor proliferation_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0004948I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• abnormal axon morphology_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0005404I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• optic nerve hypoplasia_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0006221I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• brain vacuoles_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0008025I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• abnormal dendrite morphology_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0008143I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• slow postnatal weight gain_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0008489I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• decreased cerebellar granule cell number_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0008924I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• decreased neuron number_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0008948I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• decreased oligodendrocyte number_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0009808I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• abnormal neuron differentiation_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0009937I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• postnatal lethality, complete penetrance_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0011085I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg
• cerebellum atrophy_Prkab1<Gt(RRR454)Byg>/Prkab1<Gt(RRR454)Byg>
  http://metadb.riken.jp/0014185I129P2OlaHsdC57BL6Prkab1GtRRR454BygPrkab1GtRRR454BygPrkab1GtRRR454Byg

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD28870
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD28870
• CD36965
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD36965