Victoria L. Patterson, et.al., Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway., Human molecular genetics, 2009, 18

http://rdf.ncbi.nlm.nih.gov/pubmed/19223390

Victoria L. Patterson, et.al., Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway., Human molecular genetics, 2009, 18

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tulp3<hhkr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3664273

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• pericardial edema_Smo<tm1Amc>/Smo<tm1Amc>,Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0001787I129X1SvJC3HHeHC57BL6Smotm1AmcSmotm1AmcTulp3hhkrTulp3hhkrSmotm1AmcTulp3hhkr
• increased spinal cord size_Smo<tm1Amc>/Smo<tm1Amc>,Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0002809I129X1SvJC3HHeHC57BL6Smotm1AmcSmotm1AmcTulp3hhkrTulp3hhkrSmotm1AmcTulp3hhkr
• incomplete caudal neuropore closure_Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0012707IC3HHeHC57BL6Tulp3hhkrTulp3hhkrTulp3hhkr
• oligodactyly_Shh<tm1Chg>/Shh<tm1Chg>,Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0000565I129S1Sv129X1SvJC3HHeHC57BL6Shhtm1ChgShhtm1ChgTulp3hhkrTulp3hhkrTulp3hhkrShhtm1Chg
• abnormal neural tube morphology_Shh<tm1Chg>/Shh<tm1Chg>,Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0002151I129S1Sv129X1SvJC3HHeHC57BL6Shhtm1ChgShhtm1ChgTulp3hhkrTulp3hhkrTulp3hhkrShhtm1Chg
• abnormal neural tube morphology_Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0002151IC3HHeHC57BL6Tulp3hhkrTulp3hhkrTulp3hhkr
• abnormal digit morphology_Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0002110IC3HHeHC57BL6Tulp3hhkrTulp3hhkrTulp3hhkr
• spina bifida_Shh<tm1Chg>/Shh<tm1Chg>,Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0003054I129S1Sv129X1SvJC3HHeHC57BL6Shhtm1ChgShhtm1ChgTulp3hhkrTulp3hhkrTulp3hhkrShhtm1Chg
• exencephaly_Tulp3<hhkr>/Tulp3<tm1Jng>
  http://metadb.riken.jp/0000914I129S1Sv129X1SvJC3HHeHC57BL6Tulp3hhkrTulp3tm1JngTulp3hhkrTulp3tm1Jng
• edema_Shh<tm1Chg>/Shh<tm1Chg>,Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0001785I129S1Sv129X1SvJC3HHeHC57BL6Shhtm1ChgShhtm1ChgTulp3hhkrTulp3hhkrTulp3hhkrShhtm1Chg
• polydactyly_Gli3<Xt-J>/Gli3<+>,Tulp3<hhkr>/Tulp3<+>
  http://metadb.riken.jp/0000562IC3HHeHC3HHeJC57BL6Gli3XtJGli3Tulp3hhkrTulp3Tulp3hhkrGli3Gli3XtJTulp3
• polydactyly_Gli3<Xt-J>/Gli3<+>,Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0000562IC3HHeHC3HHeJC57BL6Gli3XtJGli3Tulp3hhkrTulp3hhkrTulp3hhkrGli3XtJGli3
• edema_Tulp3<hhkr>/Tulp3<tm1Jng>
  http://metadb.riken.jp/0001785I129S1Sv129X1SvJC3HHeHC57BL6Tulp3hhkrTulp3tm1JngTulp3hhkrTulp3tm1Jng
• rib bifurcation_Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0000153IC3HHeHC57BL6Tulp3hhkrTulp3hhkrTulp3hhkr
• clinodactyly_Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0006253IC3HHeHC57BL6Tulp3hhkrTulp3hhkrTulp3hhkr
• abnormal caudal neuropore morphology_Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0012544IC3HHeHC57BL6Tulp3hhkrTulp3hhkrTulp3hhkr
• lethality throughout fetal growth and development, complete penetrance_Gli3<Xt-J>/Gli3<Xt-J>,Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0011099IC3HHeHC3HHeJC57BL6Gli3XtJGli3XtJTulp3hhkrTulp3hhkrGli3XtJTulp3hhkr
• decreased embryonic neuroepithelium thickness_Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0012703IC3HHeHC57BL6Tulp3hhkrTulp3hhkrTulp3hhkr
• abnormal neural tube morphology_Smo<tm1Amc>/Smo<tm1Amc>,Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0002151I129X1SvJC3HHeHC57BL6Smotm1AmcSmotm1AmcTulp3hhkrTulp3hhkrSmotm1AmcTulp3hhkr
• polydactyly_Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0000562IC3HHeHC57BL6Tulp3hhkrTulp3hhkrTulp3hhkr
• exencephaly_Shh<tm1Chg>/Shh<tm1Chg>,Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0000914I129S1Sv129X1SvJC3HHeHC57BL6Shhtm1ChgShhtm1ChgTulp3hhkrTulp3hhkrTulp3hhkrShhtm1Chg
• edema_Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0001785IC3HHeHC57BL6Tulp3hhkrTulp3hhkrTulp3hhkr
• spina bifida_Tulp3<hhkr>/Tulp3<tm1Jng>
  http://metadb.riken.jp/0003054I129S1Sv129X1SvJC3HHeHC57BL6Tulp3hhkrTulp3tm1JngTulp3hhkrTulp3tm1Jng
• incomplete rostral neuropore closure_Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0000928IC3HHeHC57BL6Tulp3hhkrTulp3hhkrTulp3hhkr
• polysyndactyly_Gli3<Xt-J>/Gli3<Xt-J>,Tulp3<hhkr>/Tulp3<+>
  http://metadb.riken.jp/0004083IC3HHeHC3HHeJC57BL6Gli3XtJGli3XtJTulp3hhkrTulp3Gli3XtJTulp3hhkrTulp3
• abnormal nervous system development_Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0003861IC3HHeHC57BL6Tulp3hhkrTulp3hhkrTulp3hhkr
• abnormal head morphology_Tulp3<hhkr>/Tulp3<+>
  http://metadb.riken.jp/0000432IC3HHeHC57BL6Tulp3hhkrTulp3Tulp3hhkrTulp3
• spina bifida cystica_Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0012547IC3HHeHC57BL6Tulp3hhkrTulp3hhkrTulp3hhkr
• spina bifida occulta_Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0005297IC3HHeHC57BL6Tulp3hhkrTulp3hhkrTulp3hhkr
• abnormal eye development_Tulp3<hhkr>/Tulp3<tm1Jng>
  http://metadb.riken.jp/0001286I129S1Sv129X1SvJC3HHeHC57BL6Tulp3hhkrTulp3tm1JngTulp3hhkrTulp3tm1Jng
• abnormal vertebrae development_Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0005225IC3HHeHC57BL6Tulp3hhkrTulp3hhkrTulp3hhkr
• exencephaly_Tulp3<hhkr>/Tulp3<hhkr>
  http://metadb.riken.jp/0000914IC3HHeHC57BL6Tulp3hhkrTulp3hhkrTulp3hhkr

class

http://purl.org/net/cito/citesAsAuthority

• Tulp3<hhkr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3664273

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD15306
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15306
• CD44018
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD44018
• CD19484
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD19484