Gwanghee. Lee, et.al., Response of small intestinal epithelial cells to acute disruption of cell division through CDC25 deletion., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106

http://rdf.ncbi.nlm.nih.gov/pubmed/19273838

Gwanghee. Lee, et.al., Response of small intestinal epithelial cells to acute disruption of cell division through CDC25 deletion., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cdc25a<tm1Hpw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3836585
• Cdc25a<tm1.1Hpw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3836586

class

http://purl.org/net/cito/citesAsAuthority

• Cdc25a<tm1Hpw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3836585
• Cdc25a<tm1.1Hpw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3836586

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• weight loss_Cdc25a<tm1Hpw>/Cdc25a<tm1.1Hpw>,Cdc25b<tm1Pjd>/Cdc25b<tm1Pjd>,Cdc25c<tm1Hpw>/Cdc25c<tm1Hpw>,Gt(ROSA)26Sor<tm1(cre/ERT)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0001263I129P2OlaHsd129X1SvJC57BL6Cdc25atm1HpwCdc25atm11HpwCdc25btm1PjdCdc25btm1PjdCdc25ctm1HpwCdc25ctm1HpwGtROSA26Sortm1creERTBrnGtROSA26SorGtROSA26Sortm1creERTBrnCdc25ctm1HpwGtROSA26SorCdc25atm1HpwCdc25btm1PjdCdc25atm11Hpw
• abnormal small intestine crypts of Lieberkuhn morphology_Cdc25a<tm1Hpw>/Cdc25a<tm1.1Hpw>,Cdc25b<tm1Pjd>/Cdc25b<tm1Pjd>,Cdc25c<tm1Hpw>/Cdc25c<tm1Hpw>,Gt(ROSA)26Sor<tm1(cre/ERT)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0004841I129P2OlaHsd129X1SvJC57BL6Cdc25atm1HpwCdc25atm11HpwCdc25btm1PjdCdc25btm1PjdCdc25ctm1HpwCdc25ctm1HpwGtROSA26Sortm1creERTBrnGtROSA26SorGtROSA26Sortm1creERTBrnCdc25ctm1HpwGtROSA26SorCdc25atm1HpwCdc25btm1PjdCdc25atm11Hpw
• embryonic growth retardation_Cdc25a<tm1.1Hpw>/Cdc25a<tm1.1Hpw>
  http://metadb.riken.jp/0003984I129X1SvJC57BL6Cdc25atm11HpwCdc25atm11HpwCdc25atm11Hpw
• increased apoptosis_Cdc25a<tm1.1Hpw>/Cdc25a<tm1.1Hpw>
  http://metadb.riken.jp/0006042I129X1SvJC57BL6Cdc25atm11HpwCdc25atm11HpwCdc25atm11Hpw
• decreased small intestinal villus height_Cdc25a<tm1Hpw>/Cdc25a<tm1.1Hpw>,Cdc25b<tm1Pjd>/Cdc25b<tm1Pjd>,Cdc25c<tm1Hpw>/Cdc25c<tm1Hpw>,Gt(ROSA)26Sor<tm1(cre/ERT)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0014082I129P2OlaHsd129X1SvJC57BL6Cdc25atm1HpwCdc25atm11HpwCdc25btm1PjdCdc25btm1PjdCdc25ctm1HpwCdc25ctm1HpwGtROSA26Sortm1creERTBrnGtROSA26SorGtROSA26Sortm1creERTBrnCdc25ctm1HpwGtROSA26SorCdc25atm1HpwCdc25btm1PjdCdc25atm11Hpw
• abnormal inner cell mass morphology_Cdc25a<tm1.1Hpw>/Cdc25a<tm1.1Hpw>
  http://metadb.riken.jp/0002718I129X1SvJC57BL6Cdc25atm11HpwCdc25atm11HpwCdc25atm11Hpw
• embryonic lethality between implantation and somite formation, complete penetrance_Cdc25a<tm1.1Hpw>/Cdc25a<tm1.1Hpw>
  http://metadb.riken.jp/0011096I129X1SvJC57BL6Cdc25atm11HpwCdc25atm11HpwCdc25atm11Hpw
• no abnormal phenotype detected_Cdc25a<tm1Hpw>/Cdc25a<tm1Hpw>
  http://metadb.riken.jp/0002169I129X1SvJC57BL6Cdc25atm1HpwCdc25atm1HpwCdc25atm1Hpw
• premature death_Cdc25a<tm1Hpw>/Cdc25a<tm1.1Hpw>,Cdc25b<tm1Pjd>/Cdc25b<tm1Pjd>,Cdc25c<tm1Hpw>/Cdc25c<tm1Hpw>,Gt(ROSA)26Sor<tm1(cre/ERT)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0002083I129P2OlaHsd129X1SvJC57BL6Cdc25atm1HpwCdc25atm11HpwCdc25btm1PjdCdc25btm1PjdCdc25ctm1HpwCdc25ctm1HpwGtROSA26Sortm1creERTBrnGtROSA26SorGtROSA26Sortm1creERTBrnCdc25ctm1HpwGtROSA26SorCdc25atm1HpwCdc25btm1PjdCdc25atm11Hpw
• decreased small intestine length_Cdc25a<tm1Hpw>/Cdc25a<tm1.1Hpw>,Cdc25b<tm1Pjd>/Cdc25b<tm1Pjd>,Cdc25c<tm1Hpw>/Cdc25c<tm1Hpw>,Gt(ROSA)26Sor<tm1(cre/ERT)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0013958I129P2OlaHsd129X1SvJC57BL6Cdc25atm1HpwCdc25atm11HpwCdc25btm1PjdCdc25btm1PjdCdc25ctm1HpwCdc25ctm1HpwGtROSA26Sortm1creERTBrnGtROSA26SorGtROSA26Sortm1creERTBrnCdc25ctm1HpwGtROSA26SorCdc25atm1HpwCdc25btm1PjdCdc25atm11Hpw
• abnormal small intestinal villus morphology_Cdc25a<tm1Hpw>/Cdc25a<tm1.1Hpw>,Cdc25b<tm1Pjd>/Cdc25b<tm1Pjd>,Cdc25c<tm1Hpw>/Cdc25c<tm1Hpw>,Gt(ROSA)26Sor<tm1(cre/ERT)Brn>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008108I129P2OlaHsd129X1SvJC57BL6Cdc25atm1HpwCdc25atm11HpwCdc25btm1PjdCdc25btm1PjdCdc25ctm1HpwCdc25ctm1HpwGtROSA26Sortm1creERTBrnGtROSA26SorGtROSA26Sortm1creERTBrnCdc25ctm1HpwGtROSA26SorCdc25atm1HpwCdc25btm1PjdCdc25atm11Hpw

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD14378
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD14378
• CD05628
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD05628