Xinhe. Wang, et.al., Cytoplasmic prion protein induces forebrain neurotoxicity., Biochimica et biophysica acta, 2009, 1792

http://rdf.ncbi.nlm.nih.gov/pubmed/19281844

Xinhe. Wang, et.al., Cytoplasmic prion protein induces forebrain neurotoxicity., Biochimica et biophysica acta, 2009, 1792

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO/CMV-Prnp*,-lacZ)5Mjy
  http://metadb.riken.jp/db/mgi_rdf/MGI:4365809
• Tg(tetO/CMV-Prnp*,-lacZ)33Mjy
  http://metadb.riken.jp/db/mgi_rdf/MGI:4365814

class

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO/CMV-Prnp*,-lacZ)5Mjy
  http://metadb.riken.jp/db/mgi_rdf/MGI:4365809
• Tg(tetO/CMV-Prnp*,-lacZ)33Mjy
  http://metadb.riken.jp/db/mgi_rdf/MGI:4365814

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• thin cerebral cortex_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/0,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0006254IFVBNTgtetOCMVPrnplacZ33Mjy0TgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• astrocytosis_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/Tg(tetO/CMV-Prnp*,-lacZ)33Mjy,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0003354IFVBNTgtetOCMVPrnplacZ33MjyTgtetOCMVPrnplacZ33MjyTgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• neurodegeneration_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/0,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0002229IFVBNTgtetOCMVPrnplacZ33Mjy0TgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• abnormal hippocampus morphology_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/Tg(tetO/CMV-Prnp*,-lacZ)33Mjy,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0000807IFVBNTgtetOCMVPrnplacZ33MjyTgtetOCMVPrnplacZ33MjyTgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• abnormal cell morphology_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/Tg(tetO/CMV-Prnp*,-lacZ)33Mjy,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0000358IFVBNTgtetOCMVPrnplacZ33MjyTgtetOCMVPrnplacZ33MjyTgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• abnormal cerebral cortex morphology_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/Tg(tetO/CMV-Prnp*,-lacZ)33Mjy,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0000788IFVBNTgtetOCMVPrnplacZ33MjyTgtetOCMVPrnplacZ33MjyTgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• decreased brain weight_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/0,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0002175IFVBNTgtetOCMVPrnplacZ33Mjy0TgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• limb grasping_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/Tg(tetO/CMV-Prnp*,-lacZ)33Mjy,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0001513IFVBNTgtetOCMVPrnplacZ33MjyTgtetOCMVPrnplacZ33MjyTgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• abnormal hippocampus morphology_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/0,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0000807IFVBNTgtetOCMVPrnplacZ33Mjy0TgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• astrocytosis_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/0,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0003354IFVBNTgtetOCMVPrnplacZ33Mjy0TgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• decreased body size_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/Tg(tetO/CMV-Prnp*,-lacZ)33Mjy,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0001265IFVBNTgtetOCMVPrnplacZ33MjyTgtetOCMVPrnplacZ33MjyTgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• abnormal cerebral cortex morphology_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/0,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0000788IFVBNTgtetOCMVPrnplacZ33Mjy0TgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• postnatal growth retardation_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/Tg(tetO/CMV-Prnp*,-lacZ)33Mjy,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0001732IFVBNTgtetOCMVPrnplacZ33MjyTgtetOCMVPrnplacZ33MjyTgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• circling_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/Tg(tetO/CMV-Prnp*,-lacZ)33Mjy,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0001394IFVBNTgtetOCMVPrnplacZ33MjyTgtetOCMVPrnplacZ33MjyTgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• circling_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/0,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0001394IFVBNTgtetOCMVPrnplacZ33Mjy0TgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• hyperresponsive to tactile stimuli_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/0,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0002738IFVBNTgtetOCMVPrnplacZ33Mjy0TgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• abnormal plasma membrane morphology_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/0,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0003950IFVBNTgtetOCMVPrnplacZ33Mjy0TgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• hyperactivity_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/0,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0001399IFVBNTgtetOCMVPrnplacZ33Mjy0TgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• limb grasping_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/0,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0001513IFVBNTgtetOCMVPrnplacZ33Mjy0TgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• thin cerebral cortex_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/Tg(tetO/CMV-Prnp*,-lacZ)33Mjy,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0006254IFVBNTgtetOCMVPrnplacZ33MjyTgtetOCMVPrnplacZ33MjyTgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• increased aggression towards mice_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/0,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0001353IFVBNTgtetOCMVPrnplacZ33Mjy0TgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• abnormal plasma membrane morphology_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/Tg(tetO/CMV-Prnp*,-lacZ)33Mjy,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0003950IFVBNTgtetOCMVPrnplacZ33MjyTgtetOCMVPrnplacZ33MjyTgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy
• neurodegeneration_Tg(tetO/CMV-Prnp*,-lacZ)33Mjy/Tg(tetO/CMV-Prnp*,-lacZ)33Mjy,Tg(Camk2a-rtTA)1237Kndl/0
  http://metadb.riken.jp/0002229IFVBNTgtetOCMVPrnplacZ33MjyTgtetOCMVPrnplacZ33MjyTgCamk2artTA1237Kndl0TgCamk2artTA1237KndlTgtetOCMVPrnplacZ33Mjy