Iwao. Takahashi, et.al., Important role of heparan sulfate in postnatal islet growth and insulin secretion., Biochemical and biophysical research communications, 2009, 383

http://rdf.ncbi.nlm.nih.gov/pubmed/19336225

Iwao. Takahashi, et.al., Important role of heparan sulfate in postnatal islet growth and insulin secretion., Biochemical and biophysical research communications, 2009, 383

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Extl3<tm1.1Okam>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3844734
• Extl3<tm1Okam>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3844733

class

http://purl.org/net/cito/citesAsAuthority

• Extl3<tm1.1Okam>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3844734
• Extl3<tm1Okam>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3844733

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased pancreatic beta cell mass_Extl3<tm1.1Okam>/Extl3<tm1Okam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0009114I129P2OlaHsdICRExtl3tm11OkamExtl3tm1OkamTgIns2cre25Mgn0TgIns2cre25MgnExtl3tm11OkamExtl3tm1Okam
• disorganized pancreatic islets_Extl3<tm1.1Okam>/Extl3<tm1Okam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0009254I129P2OlaHsdICRExtl3tm11OkamExtl3tm1OkamTgIns2cre25Mgn0TgIns2cre25MgnExtl3tm11OkamExtl3tm1Okam
• impaired glucose tolerance_Extl3<tm1.1Okam>/Extl3<tm1Okam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005293I129P2OlaHsdICRExtl3tm11OkamExtl3tm1OkamTgIns2cre25Mgn0TgIns2cre25MgnExtl3tm11OkamExtl3tm1Okam
• embryonic lethality, complete penetrance_Extl3<tm1.1Okam>/Extl3<tm1.1Okam>
  http://metadb.riken.jp/0011092I129P2OlaHsdICRExtl3tm11OkamExtl3tm11OkamExtl3tm11Okam
• decreased cell proliferation_Extl3<tm1.1Okam>/Extl3<tm1Okam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0000352I129P2OlaHsdICRExtl3tm11OkamExtl3tm1OkamTgIns2cre25Mgn0TgIns2cre25MgnExtl3tm11OkamExtl3tm1Okam
• decreased circulating insulin level_Extl3<tm1.1Okam>/Extl3<tm1Okam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0002727I129P2OlaHsdICRExtl3tm11OkamExtl3tm1OkamTgIns2cre25Mgn0TgIns2cre25MgnExtl3tm11OkamExtl3tm1Okam
• decreased insulin secretion_Extl3<tm1.1Okam>/Extl3<tm1Okam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003059I129P2OlaHsdICRExtl3tm11OkamExtl3tm1OkamTgIns2cre25Mgn0TgIns2cre25MgnExtl3tm11OkamExtl3tm1Okam
• decreased pancreatic beta cell number_Extl3<tm1.1Okam>/Extl3<tm1Okam>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003339I129P2OlaHsdICRExtl3tm11OkamExtl3tm1OkamTgIns2cre25Mgn0TgIns2cre25MgnExtl3tm11OkamExtl3tm1Okam

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD09289
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD09289