Cédric. Barrière, et.al., Mice thrive without Cdk4 and Cdk2., Molecular oncology, 2007, 1

http://rdf.ncbi.nlm.nih.gov/pubmed/19383288

Cédric. Barrière, et.al., Mice thrive without Cdk4 and Cdk2., Molecular oncology, 2007, 1

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cdk4<tm2Bbd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3759557
• Cdk4<tm2.1Bbd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3759558
• Cdk4<tm2.2Bbd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5705761

class

http://purl.org/net/cito/citesAsAuthority

• Cdk4<tm2Bbd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3759557
• Cdk4<tm2.1Bbd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3759558
• Cdk4<tm2.2Bbd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5705761

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• liver hypoplasia_Cdk2<tm1Sgo>/Cdk2<tm1Sgo>,Cdk4<tm2.1Bbd>/Cdk4<tm2.1Bbd>
  http://metadb.riken.jp/0000600I129S1Sv129X1SvJBALBcJC57BL6SJLCdk2tm1SgoCdk2tm1SgoCdk4tm21BbdCdk4tm21BbdCdk4tm21BbdCdk2tm1Sgo
• decreased fibroblast proliferation_Cdk2<tm1Sgo>/Cdk2<tm1Sgo>,Cdk4<tm2.1Bbd>/Cdk4<tm2.1Bbd>
  http://metadb.riken.jp/0011704I129S1Sv129X1SvJBALBcJC57BL6SJLCdk2tm1SgoCdk2tm1SgoCdk4tm21BbdCdk4tm21BbdCdk4tm21BbdCdk2tm1Sgo
• enlarged myocardial fiber_Cdk2<tm1Sgo>/Cdk2<tm1Sgo>,Cdk4<tm2.1Bbd>/Cdk4<tm2.1Bbd>
  http://metadb.riken.jp/0004564I129S1Sv129X1SvJBALBcJC57BL6SJLCdk2tm1SgoCdk2tm1SgoCdk4tm21BbdCdk4tm21BbdCdk4tm21BbdCdk2tm1Sgo
• increased susceptibility to autoimmune diabetes_Cdk2<tm2Sgo>/Cdk2<tm2Sgo>,Cdk4<tm2.1Bbd>/Cdk4<tm2.1Bbd>,Polr2a<tm1(cre/ERT2)Bbd>/?
  http://metadb.riken.jp/0004803I129S1Sv129X1SvJC57BL6SJLCdk2tm2SgoCdk2tm2SgoCdk4tm21BbdCdk4tm21BbdPolr2atm1creERT2BbdPolr2atm1creERT2BbdCdk2tm2SgoCdk4tm21Bbd
• abnormal cell cycle_Cdk2<tm1Sgo>/Cdk2<tm1Sgo>,Cdk4<tm2.1Bbd>/Cdk4<tm2.1Bbd>
  http://metadb.riken.jp/0003077I129S1Sv129X1SvJBALBcJC57BL6SJLCdk2tm1SgoCdk2tm1SgoCdk4tm21BbdCdk4tm21BbdCdk4tm21BbdCdk2tm1Sgo
• thin ventricular wall_Cdk2<tm1Sgo>/Cdk2<tm1Sgo>,Cdk4<tm2.1Bbd>/Cdk4<tm2.1Bbd>
  http://metadb.riken.jp/0000280I129S1Sv129X1SvJBALBcJC57BL6SJLCdk2tm1SgoCdk2tm1SgoCdk4tm21BbdCdk4tm21BbdCdk4tm21BbdCdk2tm1Sgo
• abnormal liver physiology_Cdk2<tm1Sgo>/Cdk2<tm1Sgo>,Cdk4<tm2.1Bbd>/Cdk4<tm2.1Bbd>
  http://metadb.riken.jp/0000609I129S1Sv129X1SvJBALBcJC57BL6SJLCdk2tm1SgoCdk2tm1SgoCdk4tm21BbdCdk4tm21BbdCdk4tm21BbdCdk2tm1Sgo
• decreased erythrocyte cell number_Cdk2<tm1Sgo>/Cdk2<tm1Sgo>,Cdk4<tm2.1Bbd>/Cdk4<tm2.1Bbd>
  http://metadb.riken.jp/0002875I129S1Sv129X1SvJBALBcJC57BL6SJLCdk2tm1SgoCdk2tm1SgoCdk4tm21BbdCdk4tm21BbdCdk4tm21BbdCdk2tm1Sgo
• abnormal fetal cardiomyocyte proliferation_Cdk2<tm1Sgo>/Cdk2<tm1Sgo>,Cdk4<tm2.1Bbd>/Cdk4<tm2.1Bbd>
  http://metadb.riken.jp/0003567I129S1Sv129X1SvJBALBcJC57BL6SJLCdk2tm1SgoCdk2tm1SgoCdk4tm21BbdCdk4tm21BbdCdk4tm21BbdCdk2tm1Sgo
• neonatal lethality, complete penetrance_Cdk2<tm1Sgo>/Cdk2<tm1Sgo>,Cdk4<tm2.1Bbd>/Cdk4<tm2.1Bbd>
  http://metadb.riken.jp/0011087I129S1Sv129X1SvJBALBcJC57BL6SJLCdk2tm1SgoCdk2tm1SgoCdk4tm21BbdCdk4tm21BbdCdk4tm21BbdCdk2tm1Sgo
• decreased body size_Cdk2<tm2Sgo>/Cdk2<tm2Sgo>,Cdk4<tm2.1Bbd>/Cdk4<tm2.1Bbd>,Polr2a<tm1(cre/ERT2)Bbd>/?
  http://metadb.riken.jp/0001265I129S1Sv129X1SvJC57BL6SJLCdk2tm2SgoCdk2tm2SgoCdk4tm21BbdCdk4tm21BbdPolr2atm1creERT2BbdPolr2atm1creERT2BbdCdk2tm2SgoCdk4tm21Bbd
• decreased body weight_Cdk2<tm1Sgo>/Cdk2<tm1Sgo>,Cdk4<tm2.1Bbd>/Cdk4<tm2.1Bbd>
  http://metadb.riken.jp/0001262I129S1Sv129X1SvJBALBcJC57BL6SJLCdk2tm1SgoCdk2tm1SgoCdk4tm21BbdCdk4tm21BbdCdk4tm21BbdCdk2tm1Sgo
• congestive heart failure_Cdk2<tm1Sgo>/Cdk2<tm1Sgo>,Cdk4<tm2.1Bbd>/Cdk4<tm2.1Bbd>
  http://metadb.riken.jp/0006138I129S1Sv129X1SvJBALBcJC57BL6SJLCdk2tm1SgoCdk2tm1SgoCdk4tm21BbdCdk4tm21BbdCdk4tm21BbdCdk2tm1Sgo
• abnormal embryo development_Cdk2<tm1Sgo>/Cdk2<+>,Cdk4<tm2.1Bbd>/Cdk4<+>
  http://metadb.riken.jp/0001672I129S1Sv129X1SvJBALBcJC57BL6SJLCdk2tm1SgoCdk2Cdk4tm21BbdCdk4Cdk4tm21BbdCdk2tm1SgoCdk4Cdk2
• abnormal definitive hematopoiesis_Cdk2<tm1Sgo>/Cdk2<tm1Sgo>,Cdk4<tm2.1Bbd>/Cdk4<tm2.1Bbd>
  http://metadb.riken.jp/0002123I129S1Sv129X1SvJBALBcJC57BL6SJLCdk2tm1SgoCdk2tm1SgoCdk4tm21BbdCdk4tm21BbdCdk4tm21BbdCdk2tm1Sgo