Lindzy F. Dodson, et.al., Targeted knock-in mice expressing mutations of CD28 reveal an essential pathway for costimulation., Molecular and cellular biology, 2009, 29

http://rdf.ncbi.nlm.nih.gov/pubmed/19398586

http://rdf.ncbi.nlm.nih.gov/pubmed/19398586

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cd28<tm2.1Jmg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3850854

class

http://purl.org/net/cito/citesAsAuthority

• Cd28<tm2.1Jmg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3850854

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased T cell proliferation_Cd28<tm1Mak>/Cd28<tm1Mak>
  http://metadb.riken.jp/0005095I129S2SvPasC57BL6Cd28tm1MakCd28tm1MakCd28tm1Mak
• decreased T cell proliferation_Cd28<tm1Jmg>/Cd28<tm1Mak>
  http://metadb.riken.jp/0005095I129S2SvPas129X1SvJC57BL6Cd28tm1JmgCd28tm1MakCd28tm1JmgCd28tm1Mak
• no abnormal phenotype detected_Cd28<tm2.1Jmg>/Cd28<tm2.1Jmg>
  http://metadb.riken.jp/0002169B6129X1Cd28tm21JmgCd28tm21JmgCd28tm21JmgCd28tm21Jmg
• decreased interleukin-2 secretion_Cd28<tm1Jmg>/Cd28<tm1Jmg>
  http://metadb.riken.jp/0008688B6129X1Cd28tm1JmgCd28tm1JmgCd28tm1JmgCd28tm1Jmg
• increased susceptibility to type I hypersensitivity reaction_Cd28<tm1Mak>/Cd28<tm1Mak>
  http://metadb.riken.jp/0005596I129S2SvPasC57BL6Cd28tm1MakCd28tm1MakCd28tm1Mak
• increased susceptibility to type I hypersensitivity reaction_Cd28<tm1Jmg>/Cd28<tm1Jmg>
  http://metadb.riken.jp/0005596B6129X1Cd28tm1JmgCd28tm1JmgCd28tm1JmgCd28tm1Jmg
• increased T cell apoptosis_Cd28<tm1Mak>/Cd28<tm1Mak>
  http://metadb.riken.jp/0006413I129S2SvPasC57BL6Cd28tm1MakCd28tm1MakCd28tm1Mak
• decreased susceptibility to experimental autoimmune encephalomyelitis_Cd28<tm1Mak>/Cd28<tm1Mak>
  http://metadb.riken.jp/0004800I129S2SvPasC57BL6Cd28tm1MakCd28tm1MakCd28tm1Mak
• decreased interleukin-2 secretion_Cd28<tm1Mak>/Cd28<tm1Mak>
  http://metadb.riken.jp/0008688I129S2SvPasC57BL6Cd28tm1MakCd28tm1MakCd28tm1Mak
• decreased susceptibility to experimental autoimmune encephalomyelitis_Cd28<tm1Jmg>/Cd28<tm1Jmg>
  http://metadb.riken.jp/0004800B6129X1Cd28tm1JmgCd28tm1JmgCd28tm1JmgCd28tm1Jmg