Shudan. Shen, et.al., The importance of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kilodaltons sterile-alpha motif domain in thymic selection and T-cell activation., Blood, 2009, 114

http://rdf.ncbi.nlm.nih.gov/pubmed/19401562

Shudan. Shen, et.al., The importance of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kilodaltons sterile-alpha motif domain in thymic selection and T-cell activation., Blood, 2009, 114

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Lcp2<tm1.1Wz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3850705

class

http://purl.org/net/cito/citesAsAuthority

• Lcp2<tm1.1Wz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3850705

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal T cell subpopulation ratio_Lcp2<tm1.1Wz>/Lcp2<tm1.1Wz>
  http://metadb.riken.jp/0003944B6CgLcp2tm11WzLcp2tm11WzLcp2tm11WzLcp2tm11Wz
• decreased double-negative T cell number_Lcp2<tm1.1Wz>/Lcp2<tm1.1Wz>
  http://metadb.riken.jp/0005089B6CgLcp2tm11WzLcp2tm11WzLcp2tm11WzLcp2tm11Wz
• lymph node hypoplasia_Lcp2<tm1.1Wz>/Lcp2<tm1.1Wz>
  http://metadb.riken.jp/0008101B6CgLcp2tm11WzLcp2tm11WzLcp2tm11WzLcp2tm11Wz
• decreased single-positive T cell number_Grap2<tm1Amch>/Grap2<tm1Amch>,Lcp2<tm1.1Wz>/Lcp2<tm1.1Wz>
  http://metadb.riken.jp/0008083I129S1Sv129X1SvJC57BL6Grap2tm1AmchGrap2tm1AmchLcp2tm11WzLcp2tm11WzGrap2tm1AmchLcp2tm11Wz
• decreased T cell number_Lcp2<tm1.1Wz>/Lcp2<tm1.1Wz>
  http://metadb.riken.jp/0005018B6CgLcp2tm11WzLcp2tm11WzLcp2tm11WzLcp2tm11Wz
• decreased thymocyte number_Lcp2<tm1.1Wz>/Lcp2<tm1.1Wz>
  http://metadb.riken.jp/0000715B6CgLcp2tm11WzLcp2tm11WzLcp2tm11WzLcp2tm11Wz
• abnormal effector T cell morphology_Lcp2<tm1.1Wz>/Lcp2<tm1.1Wz>
  http://metadb.riken.jp/0002435B6CgLcp2tm11WzLcp2tm11WzLcp2tm11WzLcp2tm11Wz
• abnormal T cell differentiation_Lcp2<tm1.1Wz>/Lcp2<tm1.1Wz>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0
  http://metadb.riken.jp/0002145IC57BL6C57BL6JDBA2JLcp2tm11WzLcp2tm11WzTgTcraHYTcrbHY71Vbo0Lcp2tm11WzTgTcraHYTcrbHY71Vbo
• abnormal T cell differentiation_Grap2<tm1Amch>/Grap2<tm1Amch>,Lcp2<tm1.1Wz>/Lcp2<tm1.1Wz>
  http://metadb.riken.jp/0002145I129S1Sv129X1SvJC57BL6Grap2tm1AmchGrap2tm1AmchLcp2tm11WzLcp2tm11WzGrap2tm1AmchLcp2tm11Wz
• increased double-negative T cell number_Lcp2<tm1.1Wz>/Lcp2<tm1.1Wz>
  http://metadb.riken.jp/0005090B6CgLcp2tm11WzLcp2tm11WzLcp2tm11WzLcp2tm11Wz
• decreased CD8-positive, alpha-beta T cell number_Lcp2<tm1.1Wz>/Lcp2<tm1.1Wz>
  http://metadb.riken.jp/0008079B6CgLcp2tm11WzLcp2tm11WzLcp2tm11WzLcp2tm11Wz
• decreased CD4-positive, alpha beta T cell number_Grap2<tm1Amch>/Grap2<tm1Amch>,Lcp2<tm1.1Wz>/Lcp2<tm1.1Wz>
  http://metadb.riken.jp/0008075I129S1Sv129X1SvJC57BL6Grap2tm1AmchGrap2tm1AmchLcp2tm11WzLcp2tm11WzGrap2tm1AmchLcp2tm11Wz
• decreased interleukin-2 secretion_Lcp2<tm1.1Wz>/Lcp2<tm1.1Wz>
  http://metadb.riken.jp/0008688B6CgLcp2tm11WzLcp2tm11WzLcp2tm11WzLcp2tm11Wz
• small thymus_Lcp2<tm1.1Wz>/Lcp2<tm1.1Wz>
  http://metadb.riken.jp/0000706B6CgLcp2tm11WzLcp2tm11WzLcp2tm11WzLcp2tm11Wz
• abnormal T cell differentiation_Lcp2<tm1.1Wz>/Lcp2<tm1.1Wz>
  http://metadb.riken.jp/0002145B6CgLcp2tm11WzLcp2tm11WzLcp2tm11WzLcp2tm11Wz
• decreased CD4-positive, alpha beta T cell number_Lcp2<tm1.1Wz>/Lcp2<tm1.1Wz>
  http://metadb.riken.jp/0008075B6CgLcp2tm11WzLcp2tm11WzLcp2tm11WzLcp2tm11Wz
• decreased T cell proliferation_Lcp2<tm1.1Wz>/Lcp2<tm1.1Wz>
  http://metadb.riken.jp/0005095B6CgLcp2tm11WzLcp2tm11WzLcp2tm11WzLcp2tm11Wz
• decreased CD8-positive, alpha-beta T cell number_Grap2<tm1Amch>/Grap2<tm1Amch>,Lcp2<tm1.1Wz>/Lcp2<tm1.1Wz>
  http://metadb.riken.jp/0008079I129S1Sv129X1SvJC57BL6Grap2tm1AmchGrap2tm1AmchLcp2tm11WzLcp2tm11WzGrap2tm1AmchLcp2tm11Wz
• decreased double-positive T cell number_Grap2<tm1Amch>/Grap2<tm1Amch>,Lcp2<tm1.1Wz>/Lcp2<tm1.1Wz>
  http://metadb.riken.jp/0005092I129S1Sv129X1SvJC57BL6Grap2tm1AmchGrap2tm1AmchLcp2tm11WzLcp2tm11WzGrap2tm1AmchLcp2tm11Wz

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD44710
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD44710