Sungeun. Lee, et.al., Theca-specific estrogen receptor-alpha knockout mice lose fertility prematurely., Endocrinology, 2009, 150

http://rdf.ncbi.nlm.nih.gov/pubmed/19423761

Sungeun. Lee, et.al., Theca-specific estrogen receptor-alpha knockout mice lose fertility prematurely., Endocrinology, 2009, 150

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• ovary cysts_Esr1<tm1.2Mma>/Esr1<tm1.2Mma>,Tg(Cyp17a1-icre)AJayko/0
  http://metadb.riken.jp/0002016I129S2SvPasC57BL6SJLEsr1tm12MmaEsr1tm12MmaTgCyp17a1icreAJayko0Esr1tm12MmaTgCyp17a1icreAJayko
• increased circulating testosterone level_Esr1<tm1.2Mma>/Esr1<tm1.2Mma>,Tg(Cyp17a1-icre)AJayko/0
  http://metadb.riken.jp/0002781I129S2SvPasC57BL6SJLEsr1tm12MmaEsr1tm12MmaTgCyp17a1icreAJayko0Esr1tm12MmaTgCyp17a1icreAJayko
• decreased corpora lutea number_Esr1<tm1.2Mma>/Esr1<tm1.2Mma>,Tg(Cyp17a1-icre)AJayko/0
  http://metadb.riken.jp/0002680I129S2SvPasC57BL6SJLEsr1tm12MmaEsr1tm12MmaTgCyp17a1icreAJayko0Esr1tm12MmaTgCyp17a1icreAJayko
• abnormal estrous cycle_Esr1<tm1.2Mma>/Esr1<tm1.2Mma>,Tg(Cyp17a1-icre)AJayko/0
  http://metadb.riken.jp/0001927I129S2SvPasC57BL6SJLEsr1tm12MmaEsr1tm12MmaTgCyp17a1icreAJayko0Esr1tm12MmaTgCyp17a1icreAJayko
• prolonged diestrus_Esr1<tm1.2Mma>/Esr1<tm1.2Mma>,Tg(Cyp17a1-icre)AJayko/0
  http://metadb.riken.jp/0009011I129S2SvPasC57BL6SJLEsr1tm12MmaEsr1tm12MmaTgCyp17a1icreAJayko0Esr1tm12MmaTgCyp17a1icreAJayko
• increased theca cell number_Esr1<tm1.2Mma>/Esr1<tm1.2Mma>,Tg(Cyp17a1-icre)AJayko/0
  http://metadb.riken.jp/0009371I129S2SvPasC57BL6SJLEsr1tm12MmaEsr1tm12MmaTgCyp17a1icreAJayko0Esr1tm12MmaTgCyp17a1icreAJayko
• oocyte degeneration_Esr1<tm1.2Mma>/Esr1<tm1.2Mma>,Tg(Cyp17a1-icre)AJayko/0
  http://metadb.riken.jp/0009093I129S2SvPasC57BL6SJLEsr1tm12MmaEsr1tm12MmaTgCyp17a1icreAJayko0Esr1tm12MmaTgCyp17a1icreAJayko
• decreased circulating luteinizing hormone level_Esr1<tm1.2Mma>/Esr1<tm1.2Mma>,Tg(Cyp17a1-icre)AJayko/0
  http://metadb.riken.jp/0002773I129S2SvPasC57BL6SJLEsr1tm12MmaEsr1tm12MmaTgCyp17a1icreAJayko0Esr1tm12MmaTgCyp17a1icreAJayko
• ovary hemorrhage_Esr1<tm1.2Mma>/Esr1<tm1.2Mma>,Tg(Cyp17a1-icre)AJayko/0
  http://metadb.riken.jp/0004834I129S2SvPasC57BL6SJLEsr1tm12MmaEsr1tm12MmaTgCyp17a1icreAJayko0Esr1tm12MmaTgCyp17a1icreAJayko
• abnormal ovarian follicle number_Esr1<tm1.2Mma>/Esr1<tm1.2Mma>,Tg(Cyp17a1-icre)AJayko/0
  http://metadb.riken.jp/0008871I129S2SvPasC57BL6SJLEsr1tm12MmaEsr1tm12MmaTgCyp17a1icreAJayko0Esr1tm12MmaTgCyp17a1icreAJayko
• abnormal ovary morphology_Esr1<tm1.2Mma>/Esr1<tm1.2Mma>,Tg(Cyp17a1-icre)AJayko/0
  http://metadb.riken.jp/0001126I129S2SvPasC57BL6SJLEsr1tm12MmaEsr1tm12MmaTgCyp17a1icreAJayko0Esr1tm12MmaTgCyp17a1icreAJayko
• abnormal theca folliculi_Esr1<tm1.2Mma>/Esr1<tm1.2Mma>,Tg(Cyp17a1-icre)AJayko/0
  http://metadb.riken.jp/0009365I129S2SvPasC57BL6SJLEsr1tm12MmaEsr1tm12MmaTgCyp17a1icreAJayko0Esr1tm12MmaTgCyp17a1icreAJayko
• early reproductive senescence_Esr1<tm1.2Mma>/Esr1<tm1.2Mma>,Tg(Cyp17a1-icre)AJayko/0
  http://metadb.riken.jp/0008995I129S2SvPasC57BL6SJLEsr1tm12MmaEsr1tm12MmaTgCyp17a1icreAJayko0Esr1tm12MmaTgCyp17a1icreAJayko
• abnormal superovulation_Esr1<tm1.2Mma>/Esr1<tm1.2Mma>,Tg(Cyp17a1-icre)AJayko/0
  http://metadb.riken.jp/0009648I129S2SvPasC57BL6SJLEsr1tm12MmaEsr1tm12MmaTgCyp17a1icreAJayko0Esr1tm12MmaTgCyp17a1icreAJayko
• female infertility_Esr1<tm1.2Mma>/Esr1<tm1.2Mma>,Tg(Cyp17a1-icre)AJayko/0
  http://metadb.riken.jp/0001926I129S2SvPasC57BL6SJLEsr1tm12MmaEsr1tm12MmaTgCyp17a1icreAJayko0Esr1tm12MmaTgCyp17a1icreAJayko
• increased gonadotroph cell number_Esr1<tm1.2Mma>/Esr1<tm1.2Mma>,Tg(Cyp17a1-icre)AJayko/0
  http://metadb.riken.jp/0008334I129S2SvPasC57BL6SJLEsr1tm12MmaEsr1tm12MmaTgCyp17a1icreAJayko0Esr1tm12MmaTgCyp17a1icreAJayko