Ji-Song. Guan, et.al., HDAC2 negatively regulates memory formation and synaptic plasticity., Nature, 2009, 459

http://rdf.ncbi.nlm.nih.gov/pubmed/19424149

Ji-Song. Guan, et.al., HDAC2 negatively regulates memory formation and synaptic plasticity., Nature, 2009, 459

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mapt<tm3(Hdac2)Jae>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3844982
• Hdac2<tm1.2Rdp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3844984
• Hdac2<tm1.1Rdp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3844983
• Mapt<tm2(Hdac1)Jae>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3844981

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal hippocampus pyramidal cell morphology_Mapt<tm3(Hdac2)Jae>/Mapt<tm3(Hdac2)Jae>
  http://metadb.riken.jp/0009940I129S4SvJaeC57BL6Mapttm3Hdac2JaeMapttm3Hdac2JaeMapttm3Hdac2Jae
• abnormal dentate gyrus morphology_Hdac2<tm1.2Rdp>/Hdac2<tm1.2Rdp>
  http://metadb.riken.jp/0000812I129S4SvJaeC57BL6FVBNHdac2tm12RdpHdac2tm12RdpHdac2tm12Rdp
• abnormal dentate gyrus morphology_Mapt<tm3(Hdac2)Jae>/Mapt<tm3(Hdac2)Jae>
  http://metadb.riken.jp/0000812I129S4SvJaeC57BL6Mapttm3Hdac2JaeMapttm3Hdac2JaeMapttm3Hdac2Jae
• reduced fertility_Hdac2<tm1.2Rdp>/Hdac2<tm1.2Rdp>
  http://metadb.riken.jp/0001921I129S4SvJaeC57BL6FVBNHdac2tm12RdpHdac2tm12RdpHdac2tm12Rdp
• abnormal spatial working memory_Mapt<tm3(Hdac2)Jae>/Mapt<tm3(Hdac2)Jae>
  http://metadb.riken.jp/0008428I129S4SvJaeC57BL6Mapttm3Hdac2JaeMapttm3Hdac2JaeMapttm3Hdac2Jae
• decreased body size_Hdac2<tm1.2Rdp>/Hdac2<tm1.2Rdp>
  http://metadb.riken.jp/0001265I129S4SvJaeC57BL6FVBNHdac2tm12RdpHdac2tm12RdpHdac2tm12Rdp
• enhanced contextual conditioning behavior_Hdac2<tm1.2Rdp>/Hdac2<tm1.2Rdp>
  http://metadb.riken.jp/0009453I129S4SvJaeC57BL6FVBNHdac2tm12RdpHdac2tm12RdpHdac2tm12Rdp
• abnormal spatial learning_Mapt<tm3(Hdac2)Jae>/Mapt<tm3(Hdac2)Jae>
  http://metadb.riken.jp/0001463I129S4SvJaeC57BL6Mapttm3Hdac2JaeMapttm3Hdac2JaeMapttm3Hdac2Jae
• reduced long term potentiation_Mapt<tm3(Hdac2)Jae>/Mapt<tm3(Hdac2)Jae>
  http://metadb.riken.jp/0001473I129S4SvJaeC57BL6Mapttm3Hdac2JaeMapttm3Hdac2JaeMapttm3Hdac2Jae
• abnormal hippocampus pyramidal cell morphology_Mapt<tm2(Hdac1)Jae>/Mapt<tm2(Hdac1)Jae>
  http://metadb.riken.jp/0009940I129S4SvJaeC57BL6Mapttm2Hdac1JaeMapttm2Hdac1JaeMapttm2Hdac1Jae
• impaired contextual conditioning behavior_Mapt<tm3(Hdac2)Jae>/Mapt<tm3(Hdac2)Jae>
  http://metadb.riken.jp/0009454I129S4SvJaeC57BL6Mapttm3Hdac2JaeMapttm3Hdac2JaeMapttm3Hdac2Jae
• abnormal hippocampus CA1 region morphology_Hdac2<tm1.2Rdp>/Hdac2<tm1.2Rdp>
  http://metadb.riken.jp/0008263I129S4SvJaeC57BL6FVBNHdac2tm12RdpHdac2tm12RdpHdac2tm12Rdp
• abnormal hippocampus CA1 region morphology_Mapt<tm3(Hdac2)Jae>/Mapt<tm3(Hdac2)Jae>
  http://metadb.riken.jp/0008263I129S4SvJaeC57BL6Mapttm3Hdac2JaeMapttm3Hdac2JaeMapttm3Hdac2Jae
• prenatal lethality, incomplete penetrance_Hdac2<tm1.2Rdp>/Hdac2<tm1.2Rdp>
  http://metadb.riken.jp/0011101I129S4SvJaeC57BL6FVBNHdac2tm12RdpHdac2tm12RdpHdac2tm12Rdp
• enhanced long term potentiation_Hdac2<tm1.2Rdp>/Hdac2<tm1.2Rdp>
  http://metadb.riken.jp/0003008I129S4SvJaeC57BL6FVBNHdac2tm12RdpHdac2tm12RdpHdac2tm12Rdp
• abnormal hippocampus pyramidal cell morphology_Hdac2<tm1.2Rdp>/Hdac2<tm1.2Rdp>
  http://metadb.riken.jp/0009940I129S4SvJaeC57BL6FVBNHdac2tm12RdpHdac2tm12RdpHdac2tm12Rdp

class

http://purl.org/net/cito/citesAsAuthority

• Mapt<tm3(Hdac2)Jae>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3844982
• Hdac2<tm1.2Rdp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3844984
• Hdac2<tm1.1Rdp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3844983
• Mapt<tm2(Hdac1)Jae>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3844981