Sylvia A. Vetrone, et.al., Osteopontin promotes fibrosis in dystrophic mouse muscle by modulating immune cell subsets and intramuscular TGF-beta., The Journal of clinical investigation, 2009, 119

http://rdf.ncbi.nlm.nih.gov/pubmed/19451692

Sylvia A. Vetrone, et.al., Osteopontin promotes fibrosis in dystrophic mouse muscle by modulating immune cell subsets and intramuscular TGF-beta., The Journal of clinical investigation, 2009, 119

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased T cell number_Dmd<mdx>/Dmd<mdx>,Spp1<tm1Blh>/Spp1<tm1Blh>
  http://metadb.riken.jp/0005015I129S6SvEvTacC57BL6C57BL10C57BL10ScSnDmdmdxDmdmdxSpp1tm1BlhSpp1tm1BlhSpp1tm1BlhDmdmdx
• decreased granulocyte number_Dmd<mdx>/Dmd<mdx>,Spp1<tm1Blh>/Spp1<tm1Blh>
  http://metadb.riken.jp/0000334I129S6SvEvTacC57BL6C57BL10C57BL10ScSnDmdmdxDmdmdxSpp1tm1BlhSpp1tm1BlhSpp1tm1BlhDmdmdx
• increased interleukin-12 secretion_Dmd<mdx>/Y
  http://metadb.riken.jp/0008663C57BL10ScSnDmdmdxJDmdmdxYDmdmdx
• increased interferon-gamma secretion_Dmd<mdx>/Dmd<mdx>
  http://metadb.riken.jp/0008566C57BL10ScSnDmdmdxJDmdmdxDmdmdxDmdmdx
• decreased T cell number_Dmd<mdx>/Y,Spp1<tm1Blh>/Spp1<tm1Blh>
  http://metadb.riken.jp/0005018I129S6SvEvTacC57BL6C57BL10C57BL10ScSnDmdmdxYSpp1tm1BlhSpp1tm1BlhSpp1tm1BlhDmdmdx
• abnormal muscle physiology_Dmd<mdx>/Y,Spp1<tm1Blh>/Spp1<tm1Blh>
  http://metadb.riken.jp/0002106I129S6SvEvTacC57BL6C57BL10C57BL10ScSnDmdmdxYSpp1tm1BlhSpp1tm1BlhSpp1tm1BlhDmdmdx
• increased interleukin-6 secretion_Dmd<mdx>/Y
  http://metadb.riken.jp/0008705C57BL10ScSnDmdmdxJDmdmdxYDmdmdx
• decreased neutrophil cell number_Dmd<mdx>/Y,Spp1<tm1Blh>/Spp1<tm1Blh>
  http://metadb.riken.jp/0000222I129S6SvEvTacC57BL6C57BL10C57BL10ScSnDmdmdxYSpp1tm1BlhSpp1tm1BlhSpp1tm1BlhDmdmdx
• increased tumor necrosis factor secretion_Dmd<mdx>/Dmd<mdx>
  http://metadb.riken.jp/0008560C57BL10ScSnDmdmdxJDmdmdxDmdmdxDmdmdx
• abnormal physical strength_Dmd<mdx>/Y,Spp1<tm1Blh>/Spp1<tm1Blh>
  http://metadb.riken.jp/0004262I129S6SvEvTacC57BL6C57BL10C57BL10ScSnDmdmdxYSpp1tm1BlhSpp1tm1BlhSpp1tm1BlhDmdmdx
• increased tumor necrosis factor secretion_Dmd<mdx>/Y
  http://metadb.riken.jp/0008560C57BL10ScSnDmdmdxJDmdmdxYDmdmdx
• increased interleukin-6 secretion_Dmd<mdx>/Dmd<mdx>
  http://metadb.riken.jp/0008705C57BL10ScSnDmdmdxJDmdmdxDmdmdxDmdmdx
• increased T cell number_Dmd<mdx>/Y,Spp1<tm1Blh>/Spp1<tm1Blh>
  http://metadb.riken.jp/0005015I129S6SvEvTacC57BL6C57BL10C57BL10ScSnDmdmdxYSpp1tm1BlhSpp1tm1BlhSpp1tm1BlhDmdmdx
• increased regulatory T cell number_Dmd<mdx>/Y,Spp1<tm1Blh>/Spp1<tm1Blh>
  http://metadb.riken.jp/0004973I129S6SvEvTacC57BL6C57BL10C57BL10ScSnDmdmdxYSpp1tm1BlhSpp1tm1BlhSpp1tm1BlhDmdmdx
• increased interferon-gamma secretion_Dmd<mdx>/Y
  http://metadb.riken.jp/0008566C57BL10ScSnDmdmdxJDmdmdxYDmdmdx
• abnormal muscle physiology_Dmd<mdx>/Dmd<mdx>,Spp1<tm1Blh>/Spp1<tm1Blh>
  http://metadb.riken.jp/0002106I129S6SvEvTacC57BL6C57BL10C57BL10ScSnDmdmdxDmdmdxSpp1tm1BlhSpp1tm1BlhSpp1tm1BlhDmdmdx
• increased interleukin-4 secretion_Dmd<mdx>/Dmd<mdx>
  http://metadb.riken.jp/0008699C57BL10ScSnDmdmdxJDmdmdxDmdmdxDmdmdx
• increased regulatory T cell number_Dmd<mdx>/Dmd<mdx>,Spp1<tm1Blh>/Spp1<tm1Blh>
  http://metadb.riken.jp/0004973I129S6SvEvTacC57BL6C57BL10C57BL10ScSnDmdmdxDmdmdxSpp1tm1BlhSpp1tm1BlhSpp1tm1BlhDmdmdx
• decreased T cell number_Dmd<mdx>/Dmd<mdx>,Spp1<tm1Blh>/Spp1<tm1Blh>
  http://metadb.riken.jp/0005018I129S6SvEvTacC57BL6C57BL10C57BL10ScSnDmdmdxDmdmdxSpp1tm1BlhSpp1tm1BlhSpp1tm1BlhDmdmdx
• increased interleukin-12 secretion_Dmd<mdx>/Dmd<mdx>
  http://metadb.riken.jp/0008663C57BL10ScSnDmdmdxJDmdmdxDmdmdxDmdmdx
• increased interleukin-4 secretion_Dmd<mdx>/Y
  http://metadb.riken.jp/0008699C57BL10ScSnDmdmdxJDmdmdxYDmdmdx
• increased interleukin-2 secretion_Dmd<mdx>/Dmd<mdx>
  http://metadb.riken.jp/0008687C57BL10ScSnDmdmdxJDmdmdxDmdmdxDmdmdx
• decreased granulocyte number_Dmd<mdx>/Y,Spp1<tm1Blh>/Spp1<tm1Blh>
  http://metadb.riken.jp/0000334I129S6SvEvTacC57BL6C57BL10C57BL10ScSnDmdmdxYSpp1tm1BlhSpp1tm1BlhSpp1tm1BlhDmdmdx
• abnormal physical strength_Dmd<mdx>/Dmd<mdx>,Spp1<tm1Blh>/Spp1<tm1Blh>
  http://metadb.riken.jp/0004262I129S6SvEvTacC57BL6C57BL10C57BL10ScSnDmdmdxDmdmdxSpp1tm1BlhSpp1tm1BlhSpp1tm1BlhDmdmdx
• increased interleukin-2 secretion_Dmd<mdx>/Y
  http://metadb.riken.jp/0008687C57BL10ScSnDmdmdxJDmdmdxYDmdmdx
• decreased neutrophil cell number_Dmd<mdx>/Dmd<mdx>,Spp1<tm1Blh>/Spp1<tm1Blh>
  http://metadb.riken.jp/0000222I129S6SvEvTacC57BL6C57BL10C57BL10ScSnDmdmdxDmdmdxSpp1tm1BlhSpp1tm1BlhSpp1tm1BlhDmdmdx

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased interleukin-4 secretion in RBRC03296
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1005751
• increased tumor necrosis factor secretion in RBRC03296
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1005747
• increased interleukin-2 secretion in RBRC03296
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1005750
• increased interferon-gamma secretion in RBRC03296
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1005748
• increased interleukin-12 secretion in RBRC03296
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1005749
• increased interleukin-6 secretion in RBRC03296
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1005752