Yingjie. Wu, et.al., Elevated levels of insulin-like growth factor (IGF)-I in serum rescue the severe growth retardation of IGF-I null mice., Endocrinology, 2009, 150

http://rdf.ncbi.nlm.nih.gov/pubmed/19497975

Yingjie. Wu, et.al., Elevated levels of insulin-like growth factor (IGF)-I in serum rescue the severe growth retardation of IGF-I null mice., Endocrinology, 2009, 150

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Ttr-Igf1)1Sykr
  http://metadb.riken.jp/db/mgi_rdf/MGI:4455320

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased body weight_Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0001260FVBNTgTtrIgf11SykrTgTtrIgf11Sykr0TgTtrIgf11Sykr
• decreased percent body fat/body weight_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0005459FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• decreased birth body size_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0009703FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• abnormal insulin-like growth factor I level_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0008831FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• prolonged proestrus_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0009014FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• increased circulating insulin-like growth factor I level_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0004702FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• abnormal corpus luteum morphology_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0002679FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• decreased gonadal fat pad weight_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0009283FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• decreased percent body fat/body weight_Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0005459FVBNTgTtrIgf11SykrTgTtrIgf11Sykr0TgTtrIgf11Sykr
• increased body length_Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0001257FVBNTgTtrIgf11SykrTgTtrIgf11Sykr0TgTtrIgf11Sykr
• abnormal superovulation_Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0009648FVBNTgTtrIgf11SykrTgTtrIgf11Sykr0TgTtrIgf11Sykr
• increased spleen weight_Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0004952FVBNTgTtrIgf11SykrTgTtrIgf11Sykr0TgTtrIgf11Sykr
• increased circulating insulin-like growth factor I level_Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0004702FVBNTgTtrIgf11SykrTgTtrIgf11Sykr0TgTtrIgf11Sykr
• decreased circulating insulin level_Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0002727FVBNTgTtrIgf11SykrTgTtrIgf11Sykr0TgTtrIgf11Sykr
• ovary hypoplasia_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0005158FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• decreased total body fat amount_Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0010025FVBNTgTtrIgf11SykrTgTtrIgf11Sykr0TgTtrIgf11Sykr
• increased body length_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0001257FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• decreased gonadal fat pad weight_Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0009283FVBNTgTtrIgf11SykrTgTtrIgf11Sykr0TgTtrIgf11Sykr
• reduced female fertility_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0001923FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• abnormal branching of the mammary ductal tree_Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0000662FVBNTgTtrIgf11SykrTgTtrIgf11Sykr0TgTtrIgf11Sykr
• abnormal endometrial gland development_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0013400FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• prolonged diestrus_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0009011FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• decreased endometrial gland number_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0009096FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• increased kidney weight_Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0003917FVBNTgTtrIgf11SykrTgTtrIgf11Sykr0TgTtrIgf11Sykr
• myometrium hypoplasia_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0009090FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• decreased total body fat amount_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0010025FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• decreased litter size_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0001935FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• abnormal estrous cycle_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0001927FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• abnormal endometrium morphology_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0004896FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• short estrus_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0009018FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• endometrium hypoplasia_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0009091FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• abnormal branching of the mammary ductal tree_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0000662FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• abnormal mature ovarian follicle morphology_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0009364FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• decreased circulating insulin level_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0002727FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• abnormal superovulation_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0009648FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• increased spleen weight_Igf1<tm1.1Dlr>/Igf1<tm1.1Dlr>,Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0004952FVBCgIgf1tm11DlrTgTtrIgf11SykrIgf1tm11DlrIgf1tm11DlrTgTtrIgf11Sykr0TgTtrIgf11SykrIgf1tm11Dlr
• increased liver weight_Tg(Ttr-Igf1)1Sykr/0
  http://metadb.riken.jp/0002981FVBNTgTtrIgf11SykrTgTtrIgf11Sykr0TgTtrIgf11Sykr

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Ttr-Igf1)1Sykr
  http://metadb.riken.jp/db/mgi_rdf/MGI:4455320