Keiichiro. Iwao, et.al., Heparan sulfate deficiency leads to Peters anomaly in mice by disturbing neural crest TGF-beta2 signaling., The Journal of clinical investigation, 2009, 119

http://rdf.ncbi.nlm.nih.gov/pubmed/19509472

Keiichiro. Iwao, et.al., Heparan sulfate deficiency leads to Peters anomaly in mice by disturbing neural crest TGF-beta2 signaling., The Journal of clinical investigation, 2009, 119

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• cleft secondary palate_Ext1<tm1Yama>/Ext1<tm1Yama>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0009890B6CgExt1tm1YamaTgWnt1cre11RthExt1tm1YamaExt1tm1YamaTgWnt1cre11Rth0TgWnt1cre11RthExt1tm1Yama
• abnormal craniofacial morphology_Ext1<tm1Yama>/Ext1<tm1Yama>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0000428B6CgExt1tm1YamaTgWnt1cre11RthExt1tm1YamaExt1tm1YamaTgWnt1cre11Rth0TgWnt1cre11RthExt1tm1Yama
• abnormal trabecular meshwork morphology_Ext1<tm1Yama>/Ext1<+>,Tg(Wnt1-cre)11Rth/0,Tgfb2<tm1Doe>/Tgfb2<+>
  http://metadb.riken.jp/0005203B6CgTgfb2tm1DoeExt1tm1YamaTgWnt1cre11RthExt1tm1YamaExt1TgWnt1cre11Rth0Tgfb2tm1DoeTgfb2Tgfb2tm1DoeTgWnt1cre11RthExt1Ext1tm1YamaTgfb2
• neonatal lethality, complete penetrance_Ext1<tm1Yama>/Ext1<tm1Yama>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0011087B6CgExt1tm1YamaTgWnt1cre11RthExt1tm1YamaExt1tm1YamaTgWnt1cre11Rth0TgWnt1cre11RthExt1tm1Yama
• abnormal aqueous drainage system morphology_Ext1<tm1Yama>/Ext1<+>,Tg(Wnt1-cre)11Rth/0,Tgfb2<tm1Doe>/Tgfb2<+>
  http://metadb.riken.jp/0005198B6CgTgfb2tm1DoeExt1tm1YamaTgWnt1cre11RthExt1tm1YamaExt1TgWnt1cre11Rth0Tgfb2tm1DoeTgfb2Tgfb2tm1DoeTgWnt1cre11RthExt1Ext1tm1YamaTgfb2
• ocular hypertension_Ext1<tm1Yama>/Ext1<+>,Tg(Wnt1-cre)11Rth/0,Tgfb2<tm1Doe>/Tgfb2<+>
  http://metadb.riken.jp/0005258B6CgTgfb2tm1DoeExt1tm1YamaTgWnt1cre11RthExt1tm1YamaExt1TgWnt1cre11Rth0Tgfb2tm1DoeTgfb2Tgfb2tm1DoeTgWnt1cre11RthExt1Ext1tm1YamaTgfb2
• decreased cranial neural crest cell proliferation_Ext1<tm1Yama>/Ext1<tm1Yama>
  http://metadb.riken.jp/0012760B6129S5Ext1tm1YamaExt1tm1YamaExt1tm1YamaExt1tm1Yama
• decreased cornea thickness_Ext1<tm1Yama>/Ext1<tm1Yama>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0005543B6CgExt1tm1YamaTgWnt1cre11RthExt1tm1YamaExt1tm1YamaTgWnt1cre11Rth0TgWnt1cre11RthExt1tm1Yama
• absent eyelids_Ext1<tm1Yama>/Ext1<tm1Yama>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0001341B6CgExt1tm1YamaTgWnt1cre11RthExt1tm1YamaExt1tm1YamaTgWnt1cre11Rth0TgWnt1cre11RthExt1tm1Yama
• abnormal corneal stroma morphology_Ext1<tm1Yama>/Ext1<tm1Yama>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0005300B6CgExt1tm1YamaTgWnt1cre11RthExt1tm1YamaExt1tm1YamaTgWnt1cre11Rth0TgWnt1cre11RthExt1tm1Yama
• abnormal canal of Schlemm morphology_Ext1<tm1Yama>/Ext1<+>,Tg(Wnt1-cre)11Rth/0,Tgfb2<tm1Doe>/Tgfb2<+>
  http://metadb.riken.jp/0005204B6CgTgfb2tm1DoeExt1tm1YamaTgWnt1cre11RthExt1tm1YamaExt1TgWnt1cre11Rth0Tgfb2tm1DoeTgfb2Tgfb2tm1DoeTgWnt1cre11RthExt1Ext1tm1YamaTgfb2
• abnormal ear morphology_Ext1<tm1Yama>/Ext1<tm1Yama>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0002102B6CgExt1tm1YamaTgWnt1cre11RthExt1tm1YamaExt1tm1YamaTgWnt1cre11Rth0TgWnt1cre11RthExt1tm1Yama
• abnormal iridocorneal angle_Ext1<tm1Yama>/Ext1<tm1Yama>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0004221B6CgExt1tm1YamaTgWnt1cre11RthExt1tm1YamaExt1tm1YamaTgWnt1cre11Rth0TgWnt1cre11RthExt1tm1Yama
• decreased cranial neural crest cell proliferation_Ext1<tm1Yama>/Ext1<tm1Yama>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0012760B6CgExt1tm1YamaTgWnt1cre11RthExt1tm1YamaExt1tm1YamaTgWnt1cre11Rth0TgWnt1cre11RthExt1tm1Yama
• absent hard palate_Ext1<tm1Yama>/Ext1<tm1Yama>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0009894B6CgExt1tm1YamaTgWnt1cre11RthExt1tm1YamaExt1tm1YamaTgWnt1cre11Rth0TgWnt1cre11RthExt1tm1Yama
• abnormal eye morphology_Ext1<tm1Yama>/Ext1<tm1Yama>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0002092B6CgExt1tm1YamaTgWnt1cre11RthExt1tm1YamaExt1tm1YamaTgWnt1cre11Rth0TgWnt1cre11RthExt1tm1Yama
• abnormal eye anterior chamber morphology_Ext1<tm1Yama>/Ext1<tm1Yama>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0005205B6CgExt1tm1YamaTgWnt1cre11RthExt1tm1YamaExt1tm1YamaTgWnt1cre11Rth0TgWnt1cre11RthExt1tm1Yama
• iris coloboma_Ext1<tm1Yama>/Ext1<tm1Yama>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0010714B6CgExt1tm1YamaTgWnt1cre11RthExt1tm1YamaExt1tm1YamaTgWnt1cre11Rth0TgWnt1cre11RthExt1tm1Yama
• ciliary body coloboma_Ext1<tm1Yama>/Ext1<tm1Yama>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0010719B6CgExt1tm1YamaTgWnt1cre11RthExt1tm1YamaExt1tm1YamaTgWnt1cre11Rth0TgWnt1cre11RthExt1tm1Yama