Rui. Benedito, et.al., The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis., Cell, 2009, 137

http://rdf.ncbi.nlm.nih.gov/pubmed/19524514

Rui. Benedito, et.al., The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis., Cell, 2009, 137

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-Jag1)1Rha
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437720

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• fetal growth retardation_Jag1<tm1Jlew>/Jag1<tm1Jlew>,Tg(Tie1-cre)9Ref/0
  http://metadb.riken.jp/0004201I129S1Sv129X1SvJC57BL6Jag1tm1JlewJag1tm1JlewTgTie1cre9Ref0TgTie1cre9RefJag1tm1Jlew
• decreased angiogenesis_Jag1<tm1Jlew>/Jag1<tm1Grid>,Tg(Pdgfb-icre/ERT2)1Frut/0
  http://metadb.riken.jp/0005602I129S1SvC57BL6CBAJag1tm1JlewJag1tm1GridTgPdgfbicreERT21Frut0Jag1tm1JlewTgPdgfbicreERT21FrutJag1tm1Grid
• abnormal vascular branching morphogenesis_Tg(Cdh5-tTA)D5Lbjn/0,Tg(tetO-Jag1)1Rha/0
  http://metadb.riken.jp/0003227NSTgCdh5tTAD5Lbjn0TgtetOJag11Rha0TgtetOJag11RhaTgCdh5tTAD5Lbjn
• fetal growth retardation_Tg(Cdh5-tTA)D5Lbjn/0,Tg(tetO-Jag1)1Rha/0
  http://metadb.riken.jp/0004201NSTgCdh5tTAD5Lbjn0TgtetOJag11Rha0TgtetOJag11RhaTgCdh5tTAD5Lbjn
• abnormal blood vessel morphology_Jag1<tm1Jlew>/Jag1<tm1Grid>,Tg(Pdgfb-icre/ERT2)1Frut/0
  http://metadb.riken.jp/0001614I129S1SvC57BL6CBAJag1tm1JlewJag1tm1GridTgPdgfbicreERT21Frut0Jag1tm1JlewTgPdgfbicreERT21FrutJag1tm1Grid
• abnormal retinal vasculature morphology_Jag1<tm1Jlew>/Jag1<tm1Grid>,Tg(Pdgfb-icre/ERT2)1Frut/0
  http://metadb.riken.jp/0002792I129S1SvC57BL6CBAJag1tm1JlewJag1tm1GridTgPdgfbicreERT21Frut0Jag1tm1JlewTgPdgfbicreERT21FrutJag1tm1Grid
• abnormal angiogenesis_Jag1<tm1Jlew>/Jag1<tm1Grid>,Tg(Pdgfb-icre/ERT2)1Frut/0
  http://metadb.riken.jp/0000260I129S1SvC57BL6CBAJag1tm1JlewJag1tm1GridTgPdgfbicreERT21Frut0Jag1tm1JlewTgPdgfbicreERT21FrutJag1tm1Grid
• postnatal growth retardation_Jag1<tm1Jlew>/Jag1<tm1Grid>,Tg(Pdgfb-icre/ERT2)1Frut/0
  http://metadb.riken.jp/0001732I129S1SvC57BL6CBAJag1tm1JlewJag1tm1GridTgPdgfbicreERT21Frut0Jag1tm1JlewTgPdgfbicreERT21FrutJag1tm1Grid
• increased angiogenesis_Tg(Cdh5-tTA)D5Lbjn/0,Tg(tetO-Jag1)1Rha/0
  http://metadb.riken.jp/0005601NSTgCdh5tTAD5Lbjn0TgtetOJag11Rha0TgtetOJag11RhaTgCdh5tTAD5Lbjn
• hemorrhage_Tg(Cdh5-tTA)D5Lbjn/0,Tg(tetO-Jag1)1Rha/0
  http://metadb.riken.jp/0001914NSTgCdh5tTAD5Lbjn0TgtetOJag11Rha0TgtetOJag11RhaTgCdh5tTAD5Lbjn
• abnormal vascular branching morphogenesis_Jag1<tm1Jlew>/Jag1<tm1Jlew>,Tg(Tie1-cre)9Ref/0
  http://metadb.riken.jp/0003227I129S1Sv129X1SvJC57BL6Jag1tm1JlewJag1tm1JlewTgTie1cre9Ref0TgTie1cre9RefJag1tm1Jlew
• abnormal retinal vasculature morphology_Lfng<tm1Grid>/Lfng<tm1Grid>
  http://metadb.riken.jp/0002792I129S1SvLfngtm1GridLfngtm1GridLfngtm1Grid
• decreased angiogenesis_Jag1<tm1Jlew>/Jag1<tm1Jlew>,Tg(Pdgfb-icre/ERT2)1Frut/0
  http://metadb.riken.jp/0005602IC57BL6CBAJag1tm1JlewJag1tm1JlewTgPdgfbicreERT21Frut0TgPdgfbicreERT21FrutJag1tm1Jlew
• prenatal lethality, complete penetrance_Tg(Cdh5-tTA)D5Lbjn/0,Tg(tetO-Jag1)1Rha/0
  http://metadb.riken.jp/0011091NSTgCdh5tTAD5Lbjn0TgtetOJag11Rha0TgtetOJag11RhaTgCdh5tTAD5Lbjn

class

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-Jag1)1Rha
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437720