Martina. Gatzka, et.al., Altered thymic selection and increased autoimmunity caused by ectopic expression of DRAK2 during T cell development., Journal of immunology (Baltimore, Md. : 1950), 2009, 183

http://rdf.ncbi.nlm.nih.gov/pubmed/19542440

Martina. Gatzka, et.al., Altered thymic selection and increased autoimmunity caused by ectopic expression of DRAK2 during T cell development., Journal of immunology (Baltimore, Md. : 1950), 2009, 183

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Lck-Stk17b)26.1Wals
  http://metadb.riken.jp/db/mgi_rdf/MGI:4943694

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Lck-Stk17b)26.1Wals
  http://metadb.riken.jp/db/mgi_rdf/MGI:4943694

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased CD4-positive, alpha beta T cell number_Tg(Lck-Stk17b)26.1Wals/?
  http://metadb.riken.jp/0008075B6CgTgLckStk17b261WalsTgLckStk17b261WalsTgLckStk17b261Wals
• decreased thymocyte number_Tg(Lck-Stk17b)26.1Wals/?,Tg(TcraH-Y,TcrbH-Y)71Vbo/?
  http://metadb.riken.jp/0000715IC57BL6C57BL10TgLckStk17b261WalsTgTcraHYTcrbHY71VboTgLckStk17b261WalsTgTcraHYTcrbHY71Vbo
• decreased thymocyte number_Tg(Lck-Stk17b)26.1Wals/?
  http://metadb.riken.jp/0000715B6CgTgLckStk17b261WalsTgLckStk17b261WalsTgLckStk17b261Wals
• enlarged spleen_Tg(Lck-Stk17b)26.1Wals/?
  http://metadb.riken.jp/0000691B6CgTgLckStk17b261WalsTgLckStk17b261WalsTgLckStk17b261Wals
• increased spleen weight_Tg(Lck-Stk17b)26.1Wals/?
  http://metadb.riken.jp/0004952B6CgTgLckStk17b261WalsTgLckStk17b261WalsTgLckStk17b261Wals
• abnormal T cell differentiation_Tg(Lck-Stk17b)26.1Wals/?,Tg(TcraH-Y,TcrbH-Y)71Vbo/?
  http://metadb.riken.jp/0002145IC57BL6C57BL10TgLckStk17b261WalsTgTcraHYTcrbHY71VboTgLckStk17b261WalsTgTcraHYTcrbHY71Vbo
• increased CD8-positive, alpha-beta T cell number_Tg(Lck-Stk17b)26.1Wals/?,Tg(TcraH-Y,TcrbH-Y)71Vbo/?
  http://metadb.riken.jp/0008078IC57BL6C57BL10TgLckStk17b261WalsTgTcraHYTcrbHY71VboTgLckStk17b261WalsTgTcraHYTcrbHY71Vbo
• increased anti-nuclear antigen antibody level_Tg(Lck-Stk17b)26.1Wals/?
  http://metadb.riken.jp/0004794B6CgTgLckStk17b261WalsTgLckStk17b261WalsTgLckStk17b261Wals
• decreased single-positive T cell number_Tg(Lck-Stk17b)26.1Wals/?
  http://metadb.riken.jp/0008083B6CgTgLckStk17b261WalsTgLckStk17b261WalsTgLckStk17b261Wals
• increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number_Tg(Lck-Stk17b)26.1Wals/?
  http://metadb.riken.jp/0010168B6CgTgLckStk17b261WalsTgLckStk17b261WalsTgLckStk17b261Wals
• increased susceptibility to experimental autoimmune encephalomyelitis_Tg(Lck-Stk17b)26.1Wals/?
  http://metadb.riken.jp/0004799B6CgTgLckStk17b261WalsTgLckStk17b261WalsTgLckStk17b261Wals
• increased interleukin-2 secretion_Tg(Lck-Stk17b)26.1Wals/?
  http://metadb.riken.jp/0008687B6CgTgLckStk17b261WalsTgLckStk17b261WalsTgLckStk17b261Wals
• spleen hyperplasia_Tg(Lck-Stk17b)26.1Wals/?
  http://metadb.riken.jp/0000693B6CgTgLckStk17b261WalsTgLckStk17b261WalsTgLckStk17b261Wals
• decreased CD8-positive, alpha-beta T cell number_Tg(Lck-Stk17b)26.1Wals/?,Tg(TcraH-Y,TcrbH-Y)71Vbo/?
  http://metadb.riken.jp/0008079IC57BL6C57BL10TgLckStk17b261WalsTgTcraHYTcrbHY71VboTgLckStk17b261WalsTgTcraHYTcrbHY71Vbo
• increased T cell proliferation_Tg(Lck-Stk17b)26.1Wals/?
  http://metadb.riken.jp/0005348B6CgTgLckStk17b261WalsTgLckStk17b261WalsTgLckStk17b261Wals
• increased double-positive T cell number_Tg(Lck-Stk17b)26.1Wals/?
  http://metadb.riken.jp/0005091B6CgTgLckStk17b261WalsTgLckStk17b261WalsTgLckStk17b261Wals
• decreased CD8-positive, alpha-beta T cell number_Tg(Lck-Stk17b)26.1Wals/?
  http://metadb.riken.jp/0008079B6CgTgLckStk17b261WalsTgLckStk17b261WalsTgLckStk17b261Wals