Noa. Davis, et.al., Pax6 dosage requirements in iris and ciliary body differentiation., Developmental biology, 2009, 333

http://rdf.ncbi.nlm.nih.gov/pubmed/19563798

Noa. Davis, et.al., Pax6 dosage requirements in iris and ciliary body differentiation., Developmental biology, 2009, 333

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Dct-cre)1Apdn
  http://metadb.riken.jp/db/mgi_rdf/MGI:4358082

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Dct-cre)1Apdn
  http://metadb.riken.jp/db/mgi_rdf/MGI:4358082

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal iris morphology_Pax6<tm2Pgr>/Pax6<+>,Tg(CAG-EGFP,-Pax6,-lacZ)1Stoy/0,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0001322I129S1Sv129X1SvJPax6tm2PgrPax6TgCAGEGFPPax6lacZ1Stoy0TgDctcre1Apdn0Pax6TgDctcre1ApdnPax6tm2PgrTgCAGEGFPPax6lacZ1Stoy
• iris hypoplasia_Pax6<tm2Pgr>/Pax6<+>,Tg(CAG-EGFP,-Pax6,-lacZ)1Stoy/0,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0006226I129S1Sv129X1SvJPax6tm2PgrPax6TgCAGEGFPPax6lacZ1Stoy0TgDctcre1Apdn0Pax6TgDctcre1ApdnPax6tm2PgrTgCAGEGFPPax6lacZ1Stoy
• abnormal anterior eye segment morphology_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0005193I129S1Sv129X1SvJPax6tm2PgrPax6tm2PgrTgDctcre1Apdn0Pax6tm2PgrTgDctcre1Apdn
• abnormal iris morphology_Pax6<tm2Pgr>/Pax6<+>,Tg(CAG-EGFP,-Pax6*5a,-lacZ)1Stoy/0,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0001322I129S1Sv129X1SvJPax6tm2PgrPax6TgCAGEGFPPax65alacZ1Stoy0TgDctcre1Apdn0Pax6tm2PgrTgDctcre1ApdnPax6TgCAGEGFPPax65alacZ1Stoy
• abnormal iris morphology_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0001322I129S1Sv129X1SvJPax6tm2PgrPax6tm2PgrTgDctcre1Apdn0Pax6tm2PgrTgDctcre1Apdn
• mydriasis_Pax6<tm2Pgr>/Pax6<+>,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0002546I129S1Sv129X1SvJPax6tm2PgrPax6TgDctcre1Apdn0TgDctcre1ApdnPax6tm2PgrPax6
• abnormal vitreous body morphology_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0002699I129S1Sv129X1SvJPax6tm2PgrPax6tm2PgrTgDctcre1Apdn0Pax6tm2PgrTgDctcre1Apdn
• iris hypoplasia_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0006226I129S1Sv129X1SvJPax6tm2PgrPax6tm2PgrTgDctcre1Apdn0Pax6tm2PgrTgDctcre1Apdn
• irregularly shaped pupil_Pax6<tm2Pgr>/Pax6<+>,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0001319I129S1Sv129X1SvJPax6tm2PgrPax6TgDctcre1Apdn0TgDctcre1ApdnPax6tm2PgrPax6
• retina hypoplasia_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0002984I129S1Sv129X1SvJPax6tm2PgrPax6tm2PgrTgDctcre1Apdn0Pax6tm2PgrTgDctcre1Apdn
• abnormal iris morphology_Tg(CAG-EGFP,-Pax6,-lacZ)1Stoy/0,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0001322NSTgCAGEGFPPax6lacZ1Stoy0TgDctcre1Apdn0TgCAGEGFPPax6lacZ1StoyTgDctcre1Apdn
• microphthalmia_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0001297I129S1Sv129X1SvJPax6tm2PgrPax6tm2PgrTgDctcre1Apdn0Pax6tm2PgrTgDctcre1Apdn
• impaired pupillary reflex_Pax6<tm2Pgr>/Pax6<+>,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0006243I129S1Sv129X1SvJPax6tm2PgrPax6TgDctcre1Apdn0TgDctcre1ApdnPax6tm2PgrPax6
• iris hypoplasia_Pax6<tm2Pgr>/Pax6<+>,Tg(CAG-EGFP,-Pax6*5a,-lacZ)1Stoy/0,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0006226I129S1Sv129X1SvJPax6tm2PgrPax6TgCAGEGFPPax65alacZ1Stoy0TgDctcre1Apdn0Pax6tm2PgrTgDctcre1ApdnPax6TgCAGEGFPPax65alacZ1Stoy
• small lens_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0001306I129S1Sv129X1SvJPax6tm2PgrPax6tm2PgrTgDctcre1Apdn0Pax6tm2PgrTgDctcre1Apdn
• abnormal ciliary body morphology_Pax6<tm2Pgr>/Pax6<+>,Tg(CAG-EGFP,-Pax6,-lacZ)1Stoy/0,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0005099I129S1Sv129X1SvJPax6tm2PgrPax6TgCAGEGFPPax6lacZ1Stoy0TgDctcre1Apdn0Pax6TgDctcre1ApdnPax6tm2PgrTgCAGEGFPPax6lacZ1Stoy
• abnormal retinal pigment epithelium morphology_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0005201I129S1Sv129X1SvJPax6tm2PgrPax6tm2PgrTgDctcre1Apdn0Pax6tm2PgrTgDctcre1Apdn
• iris hypoplasia_Pax6<tm2Pgr>/Pax6<+>,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0006226I129S1Sv129X1SvJPax6tm2PgrPax6TgDctcre1Apdn0TgDctcre1ApdnPax6tm2PgrPax6
• abnormal ciliary body morphology_Tg(CAG-EGFP,-Pax6,-lacZ)1Stoy/0,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0005099NSTgCAGEGFPPax6lacZ1Stoy0TgDctcre1Apdn0TgCAGEGFPPax6lacZ1StoyTgDctcre1Apdn
• abnormal lens morphology_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0001303I129S1Sv129X1SvJPax6tm2PgrPax6tm2PgrTgDctcre1Apdn0Pax6tm2PgrTgDctcre1Apdn
• opacity of vitreous body_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0002700I129S1Sv129X1SvJPax6tm2PgrPax6tm2PgrTgDctcre1Apdn0Pax6tm2PgrTgDctcre1Apdn
• abnormal intraocular muscle morphology_Pax6<tm2Pgr>/Pax6<+>,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0003687I129S1Sv129X1SvJPax6tm2PgrPax6TgDctcre1Apdn0TgDctcre1ApdnPax6tm2PgrPax6
• absent ciliary body_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0013742I129S1Sv129X1SvJPax6tm2PgrPax6tm2PgrTgDctcre1Apdn0Pax6tm2PgrTgDctcre1Apdn
• cataract_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Dct-cre)1Apdn/0
  http://metadb.riken.jp/0001304I129S1Sv129X1SvJPax6tm2PgrPax6tm2PgrTgDctcre1Apdn0Pax6tm2PgrTgDctcre1Apdn