Nicolas. Vignier, et.al., Nonsense-mediated mRNA decay and ubiquitin-proteasome system regulate cardiac myosin-binding protein C mutant levels in cardiomyopathic mice., Circulation research, 2009, 105

http://rdf.ncbi.nlm.nih.gov/pubmed/19590044

Nicolas. Vignier, et.al., Nonsense-mediated mRNA decay and ubiquitin-proteasome system regulate cardiac myosin-binding protein C mutant levels in cardiomyopathic mice., Circulation research, 2009, 105

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mybpc3<tm2.1Lcrr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4836388

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• cardiac interstitial fibrosis_Mybpc3<tm2.1Lcrr>/Mybpc3<tm2.1Lcrr>
  http://metadb.riken.jp/0005608I129S2SvPasCrlBlackSwissC57BL6CD1DBA2Mybpc3tm21LcrrMybpc3tm21LcrrMybpc3tm21Lcrr
• decreased cardiac muscle contractility_Mybpc3<tm2.1Lcrr>/Mybpc3<tm2.1Lcrr>
  http://metadb.riken.jp/0005140I129S2SvPasCrlBlackSwissC57BL6CD1DBA2Mybpc3tm21LcrrMybpc3tm21LcrrMybpc3tm21Lcrr
• heart left ventricle hypertrophy_Mybpc3<tm2.1Lcrr>/Mybpc3<tm2.1Lcrr>
  http://metadb.riken.jp/0002625I129S2SvPasCrlBlackSwissC57BL6CD1DBA2Mybpc3tm21LcrrMybpc3tm21LcrrMybpc3tm21Lcrr
• enlarged myocardial fiber_Mybpc3<tm2.1Lcrr>/Mybpc3<+>
  http://metadb.riken.jp/0004564I129S2SvPasCrlBlackSwissC57BL6CD1DBA2Mybpc3tm21LcrrMybpc3Mybpc3Mybpc3tm21Lcrr
• abnormal heart left ventricle morphology_Mybpc3<tm2.1Lcrr>/Mybpc3<tm2.1Lcrr>
  http://metadb.riken.jp/0003921I129S2SvPasCrlBlackSwissC57BL6CD1DBA2Mybpc3tm21LcrrMybpc3tm21LcrrMybpc3tm21Lcrr
• enlarged myocardial fiber_Mybpc3<tm2.1Lcrr>/Mybpc3<tm2.1Lcrr>
  http://metadb.riken.jp/0004564I129S2SvPasCrlBlackSwissC57BL6CD1DBA2Mybpc3tm21LcrrMybpc3tm21LcrrMybpc3tm21Lcrr
• increased heart weight_Mybpc3<tm2.1Lcrr>/Mybpc3<tm2.1Lcrr>
  http://metadb.riken.jp/0002833I129S2SvPasCrlBlackSwissC57BL6CD1DBA2Mybpc3tm21LcrrMybpc3tm21LcrrMybpc3tm21Lcrr

class

http://purl.org/net/cito/citesAsAuthority

• Mybpc3<tm2.1Lcrr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4836388