Lisa L. Abler, et.al., Conditional gene inactivation reveals roles for Fgf10 and Fgfr2 in establishing a normal pattern of epithelial branching in the mouse lung., Developmental dynamics : an official publication of the American Association of Anatomists, 2009, 238

http://rdf.ncbi.nlm.nih.gov/pubmed/19618463

Lisa L. Abler, et.al., Conditional gene inactivation reveals roles for Fgf10 and Fgfr2 in establishing a normal pattern of epithelial branching in the mouse lung., Developmental dynamics : an official publication of the American Association of Anatomists, 2009, 238

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Fgf10<tm1.1Sms>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3526181
• Fgf10<tm1Sms>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3526180

class

http://purl.org/net/cito/citesAsAuthority

• Fgf10<tm1.1Sms>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3526181
• Fgf10<tm1Sms>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3526180

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal right lung middle lobe morphology_Fgf10<tm1Ska>/Fgf10<tm1Sms>,Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0009573I129S1Sv129S4SvJaeSor129X1SvJC57BL6CBAFgf10tm1SkaFgf10tm1SmsGtROSA26Sortm1SorGtROSA26SorTwist2tm1creDorTwist2Twist2Fgf10tm1SkaGtROSA26SorTwist2tm1creDorFgf10tm1SmsGtROSA26Sortm1Sor
• small lung lobe_Fgf10<tm1Ska>/Fgf10<tm1Sms>,Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0010976I129S1Sv129S4SvJaeSor129X1SvJC57BL6CBAFgf10tm1SkaFgf10tm1SmsGtROSA26Sortm1SorGtROSA26SorTwist2tm1creDorTwist2Twist2Fgf10tm1SkaGtROSA26SorTwist2tm1creDorFgf10tm1SmsGtROSA26Sortm1Sor
• decreased embryo size_Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(Sftpc-cre)1Blh/0
  http://metadb.riken.jp/0001698I129X1SvJC57BL6DBA2Fgfr2tm1DorFgfr2tm1DorTgSftpccre1Blh0Fgfr2tm1DorTgSftpccre1Blh
• abnormal lung development_Fgf10<tm1Ska>/Fgf10<tm1Sms>,Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0001176I129S1Sv129S4SvJaeSor129X1SvJC57BL6CBAFgf10tm1SkaFgf10tm1SmsGtROSA26Sortm1SorGtROSA26SorTwist2tm1creDorTwist2Twist2Fgf10tm1SkaGtROSA26SorTwist2tm1creDorFgf10tm1SmsGtROSA26Sortm1Sor
• abnormal right lung cranial lobe morphology_Fgf10<tm1Ska>/Fgf10<tm1Sms>,Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0009572I129S1Sv129S4SvJaeSor129X1SvJC57BL6CBAFgf10tm1SkaFgf10tm1SmsGtROSA26Sortm1SorGtROSA26SorTwist2tm1creDorTwist2Twist2Fgf10tm1SkaGtROSA26SorTwist2tm1creDorFgf10tm1SmsGtROSA26Sortm1Sor
• impaired branching involved in bronchus morphogenesis_Fgf10<tm1Ska>/Fgf10<tm1Sms>,Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0011028I129S1Sv129S4SvJaeSor129X1SvJC57BL6CBAFgf10tm1SkaFgf10tm1SmsGtROSA26Sortm1SorGtROSA26SorTwist2tm1creDorTwist2Twist2Fgf10tm1SkaGtROSA26SorTwist2tm1creDorFgf10tm1SmsGtROSA26Sortm1Sor
• absent lungs_Fgf10<tm1.1Sms>/Fgf10<tm1.1Sms>
  http://metadb.riken.jp/0001181I129S1Sv129X1SvJFgf10tm11SmsFgf10tm11SmsFgf10tm11Sms
• neonatal lethality, complete penetrance_Fgf10<tm1.1Sms>/Fgf10<tm1.1Sms>
  http://metadb.riken.jp/0011087I129S1Sv129X1SvJFgf10tm11SmsFgf10tm11SmsFgf10tm11Sms
• abnormal lung development_Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(Sftpc-cre)1Blh/0
  http://metadb.riken.jp/0001176I129X1SvJC57BL6DBA2Fgfr2tm1DorFgfr2tm1DorTgSftpccre1Blh0Fgfr2tm1DorTgSftpccre1Blh
• small lung_Fgf10<tm1Ska>/Fgf10<tm1Sms>,Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0003641I129S1Sv129S4SvJaeSor129X1SvJC57BL6CBAFgf10tm1SkaFgf10tm1SmsGtROSA26Sortm1SorGtROSA26SorTwist2tm1creDorTwist2Twist2Fgf10tm1SkaGtROSA26SorTwist2tm1creDorFgf10tm1SmsGtROSA26Sortm1Sor
• abnormal lung lobe morphology_Fgf10<tm1Ska>/Fgf10<tm1Sms>,Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0010975I129S1Sv129S4SvJaeSor129X1SvJC57BL6CBAFgf10tm1SkaFgf10tm1SmsGtROSA26Sortm1SorGtROSA26SorTwist2tm1creDorTwist2Twist2Fgf10tm1SkaGtROSA26SorTwist2tm1creDorFgf10tm1SmsGtROSA26Sortm1Sor
• impaired branching involved in bronchus morphogenesis_Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(Sftpc-cre)1Blh/0
  http://metadb.riken.jp/0011028I129X1SvJC57BL6DBA2Fgfr2tm1DorFgfr2tm1DorTgSftpccre1Blh0Fgfr2tm1DorTgSftpccre1Blh
• abnormal right lung accessory lobe morphology_Fgf10<tm1Ska>/Fgf10<tm1Sms>,Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0009571I129S1Sv129S4SvJaeSor129X1SvJC57BL6CBAFgf10tm1SkaFgf10tm1SmsGtROSA26Sortm1SorGtROSA26SorTwist2tm1creDorTwist2Twist2Fgf10tm1SkaGtROSA26SorTwist2tm1creDorFgf10tm1SmsGtROSA26Sortm1Sor
• pulmonary hypoplasia_Fgf10<tm1Ska>/Fgf10<tm1Sms>,Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0001178I129S1Sv129S4SvJaeSor129X1SvJC57BL6CBAFgf10tm1SkaFgf10tm1SmsGtROSA26Sortm1SorGtROSA26SorTwist2tm1creDorTwist2Twist2Fgf10tm1SkaGtROSA26SorTwist2tm1creDorFgf10tm1SmsGtROSA26Sortm1Sor
• lung hemorrhage_Fgf10<tm1Ska>/Fgf10<tm1Sms>,Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0001182I129S1Sv129S4SvJaeSor129X1SvJC57BL6CBAFgf10tm1SkaFgf10tm1SmsGtROSA26Sortm1SorGtROSA26SorTwist2tm1creDorTwist2Twist2Fgf10tm1SkaGtROSA26SorTwist2tm1creDorFgf10tm1SmsGtROSA26Sortm1Sor
• abnormal lung development_Fgf10<tm1.1Sms>/Fgf10<tm1.1Sms>
  http://metadb.riken.jp/0001176I129S1Sv129X1SvJFgf10tm11SmsFgf10tm11SmsFgf10tm11Sms