Bruce. Turpie, et.al., Sjögren's syndrome-like ocular surface disease in thrombospondin-1 deficient mice., The American journal of pathology, 2009, 175

http://rdf.ncbi.nlm.nih.gov/pubmed/19700744

Bruce. Turpie, et.al., Sjögren's syndrome-like ocular surface disease in thrombospondin-1 deficient mice., The American journal of pathology, 2009, 175

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cornea morphology_Thbs1<tm1Hyn>/Thbs1<tm1Hyn>
  http://metadb.riken.jp/0001312I129S2SvPasC57BL6Thbs1tm1HynThbs1tm1HynThbs1tm1Hyn
• decreased regulatory T cell number_Thbs1<tm1Hyn>/Thbs1<tm1Hyn>
  http://metadb.riken.jp/0004974I129S2SvPasC57BL6Thbs1tm1HynThbs1tm1HynThbs1tm1Hyn
• decreased interferon-gamma secretion_Thbs1<tm1Hyn>/Thbs1<tm1Hyn>
  http://metadb.riken.jp/0008567I129S2SvPasC57BL6Thbs1tm1HynThbs1tm1HynThbs1tm1Hyn
• abnormal conjunctiva goblet cell number_Thbs1<tm1Hyn>/Thbs1<tm1Hyn>
  http://metadb.riken.jp/0013462I129S2SvPasC57BL6Thbs1tm1HynThbs1tm1HynThbs1tm1Hyn
• lacrimal gland inflammation_Thbs1<tm1Hyn>/Thbs1<tm1Hyn>
  http://metadb.riken.jp/0008880I129S2SvPasC57BL6Thbs1tm1HynThbs1tm1HynThbs1tm1Hyn
• abnormal corneal epithelium morphology_Thbs1<tm1Hyn>/Thbs1<tm1Hyn>
  http://metadb.riken.jp/0006000I129S2SvPasC57BL6Thbs1tm1HynThbs1tm1HynThbs1tm1Hyn
• increased lacrimal gland apoptosis_Thbs1<tm1Hyn>/Thbs1<tm1Hyn>
  http://metadb.riken.jp/0013452I129S2SvPasC57BL6Thbs1tm1HynThbs1tm1HynThbs1tm1Hyn
• microphthalmia_Thbs1<tm1Hyn>/Thbs1<tm1Hyn>
  http://metadb.riken.jp/0001297I129S2SvPasC57BL6Thbs1tm1HynThbs1tm1HynThbs1tm1Hyn
• increased CD4-positive, alpha beta T cell number_Thbs1<tm1Hyn>/Thbs1<tm1Hyn>
  http://metadb.riken.jp/0008074I129S2SvPasC57BL6Thbs1tm1HynThbs1tm1HynThbs1tm1Hyn
• abnormal lacrimal gland physiology_Thbs1<tm1Hyn>/Thbs1<tm1Hyn>
  http://metadb.riken.jp/0001348I129S2SvPasC57BL6Thbs1tm1HynThbs1tm1HynThbs1tm1Hyn
• increased interleukin-17 secretion_Thbs1<tm1Hyn>/Thbs1<tm1Hyn>
  http://metadb.riken.jp/0008681I129S2SvPasC57BL6Thbs1tm1HynThbs1tm1HynThbs1tm1Hyn
• narrow eye opening_Thbs1<tm1Hyn>/Thbs1<tm1Hyn>
  http://metadb.riken.jp/0005287I129S2SvPasC57BL6Thbs1tm1HynThbs1tm1HynThbs1tm1Hyn
• decreased conjunctiva goblet cell number_Thbs1<tm1Hyn>/Thbs1<tm1Hyn>
  http://metadb.riken.jp/0013464I129S2SvPasC57BL6Thbs1tm1HynThbs1tm1HynThbs1tm1Hyn
• increased anti-single stranded DNA antibody level_Thbs1<tm1Hyn>/Thbs1<tm1Hyn>
  http://metadb.riken.jp/0004771I129S2SvPasC57BL6Thbs1tm1HynThbs1tm1HynThbs1tm1Hyn