Frédéric. Preitner, et.al., Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106

http://rdf.ncbi.nlm.nih.gov/pubmed/19706426

Frédéric. Preitner, et.al., Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Slc2a9<tm1.1Thor>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4361276
• Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4361278

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased circulating creatinine level_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0005553IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• decreased urine osmolality_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0002988IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• increased urine potassium level_Alb<tm1(cre/ERT2)Mtz>/Alb<+>,Slc2a9<tm1.1Thor>/Slc2a9<tm1.1Thor>
  http://metadb.riken.jp/0005619I129S2SvPasC57BL6C57BL6NAlbtm1creERT2MtzAlbSlc2a9tm11ThorSlc2a9tm11ThorAlbtm1creERT2MtzAlbSlc2a9tm11Thor
• increased urine potassium level_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0005619IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• kidney inflammation_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0001859IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• increased circulating magnesium level_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0010092IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• kidney cortex atrophy_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0011423IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• increased urine phosphate level_Alb<tm1(cre/ERT2)Mtz>/Alb<+>,Slc2a9<tm1.1Thor>/Slc2a9<+>
  http://metadb.riken.jp/0002901I129S2SvPasC57BL6C57BL6NAlbtm1creERT2MtzAlbSlc2a9tm11ThorSlc2a9Slc2a9Slc2a9tm11ThorAlbAlbtm1creERT2Mtz
• renal interstitial fibrosis_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0003215IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• increased circulating magnesium level_Slc2a9<tm1.2Thor>/Slc2a9<+>
  http://metadb.riken.jp/0010092IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9Slc2a9Slc2a9tm12Thor
• increased urine magnesium level_Alb<tm1(cre/ERT2)Mtz>/Alb<+>,Slc2a9<tm1.1Thor>/Slc2a9<tm1.1Thor>
  http://metadb.riken.jp/0011435I129S2SvPasC57BL6C57BL6NAlbtm1creERT2MtzAlbSlc2a9tm11ThorSlc2a9tm11ThorAlbtm1creERT2MtzAlbSlc2a9tm11Thor
• increased urine phosphate level_Alb<tm1(cre/ERT2)Mtz>/Alb<+>,Slc2a9<tm1.1Thor>/Slc2a9<tm1.1Thor>
  http://metadb.riken.jp/0002901I129S2SvPasC57BL6C57BL6NAlbtm1creERT2MtzAlbSlc2a9tm11ThorSlc2a9tm11ThorAlbtm1creERT2MtzAlbSlc2a9tm11Thor
• increased urine magnesium level_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0011435IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• kidney cortex cysts_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0000522IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• polydipsia_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0001426IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• increased urine sodium level_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0006316IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• decreased urine pH_Alb<tm1(cre/ERT2)Mtz>/Alb<+>,Slc2a9<tm1.1Thor>/Slc2a9<tm1.1Thor>
  http://metadb.riken.jp/0009350I129S2SvPasC57BL6C57BL6NAlbtm1creERT2MtzAlbSlc2a9tm11ThorSlc2a9tm11ThorAlbtm1creERT2MtzAlbSlc2a9tm11Thor
• tubulointerstitial nephritis_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0011405IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• hydronephrosis_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0000519IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• dilated renal tubules_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0002705IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• abnormal renal reabsorbtion_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0010107IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• increased urine sodium level_Slc2a9<tm1.2Thor>/Slc2a9<+>
  http://metadb.riken.jp/0006316IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9Slc2a9Slc2a9tm12Thor
• increased blood uric acid level_Alb<tm1(cre/ERT2)Mtz>/Alb<+>,Slc2a9<tm1.1Thor>/Slc2a9<tm1.1Thor>
  http://metadb.riken.jp/0008821I129S2SvPasC57BL6C57BL6NAlbtm1creERT2MtzAlbSlc2a9tm11ThorSlc2a9tm11ThorAlbtm1creERT2MtzAlbSlc2a9tm11Thor
• nephrolithiasis_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0002708IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• polyuria_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0001762IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• decreased body weight_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0001262IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• polyuria_Alb<tm1(cre/ERT2)Mtz>/Alb<+>,Slc2a9<tm1.1Thor>/Slc2a9<tm1.1Thor>
  http://metadb.riken.jp/0001762I129S2SvPasC57BL6C57BL6NAlbtm1creERT2MtzAlbSlc2a9tm11ThorSlc2a9tm11ThorAlbtm1creERT2MtzAlbSlc2a9tm11Thor
• increased urine magnesium level_Alb<tm1(cre/ERT2)Mtz>/Alb<+>,Slc2a9<tm1.1Thor>/Slc2a9<+>
  http://metadb.riken.jp/0011435I129S2SvPasC57BL6C57BL6NAlbtm1creERT2MtzAlbSlc2a9tm11ThorSlc2a9Slc2a9Slc2a9tm11ThorAlbAlbtm1creERT2Mtz
• decreased urine osmolality_Alb<tm1(cre/ERT2)Mtz>/Alb<+>,Slc2a9<tm1.1Thor>/Slc2a9<tm1.1Thor>
  http://metadb.riken.jp/0002988I129S2SvPasC57BL6C57BL6NAlbtm1creERT2MtzAlbSlc2a9tm11ThorSlc2a9tm11ThorAlbtm1creERT2MtzAlbSlc2a9tm11Thor
• renal tubule atrophy_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0011346IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• prenatal lethality, incomplete penetrance_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0011101IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• decreased urine pH_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0009350IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• increased blood uric acid level_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0008821IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor
• uraturia_Alb<tm1(cre/ERT2)Mtz>/Alb<+>,Slc2a9<tm1.1Thor>/Slc2a9<tm1.1Thor>
  http://metadb.riken.jp/0011537I129S2SvPasC57BL6C57BL6NAlbtm1creERT2MtzAlbSlc2a9tm11ThorSlc2a9tm11ThorAlbtm1creERT2MtzAlbSlc2a9tm11Thor
• uraturia_Slc2a9<tm1.2Thor>/Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/0011537IC57BL6C57BL6NSlc2a9tm12ThorSlc2a9tm12ThorSlc2a9tm12Thor

class

http://purl.org/net/cito/citesAsAuthority

• Slc2a9<tm1.1Thor>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4361276
• Slc2a9<tm1.2Thor>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4361278

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD22086
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD22086