Géraldine. Mollet, et.al., Podocin inactivation in mature kidneys causes focal segmental glomerulosclerosis and nephrotic syndrome., Journal of the American Society of Nephrology : JASN, 2009, 20

http://rdf.ncbi.nlm.nih.gov/pubmed/19713307

Géraldine. Mollet, et.al., Podocin inactivation in mature kidneys causes focal segmental glomerulosclerosis and nephrotic syndrome., Journal of the American Society of Nephrology : JASN, 2009, 20

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nphs2<tm3.1Antc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4845889

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0002083I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn
• expanded mesangial matrix_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0011353I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn
• increased blood urea nitrogen level_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0005565I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn
• renal interstitial fibrosis_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0003215I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn
• mesangial cell hyperplasia_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0011427I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn
• glomerulosclerosis_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0005264I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn
• renal tubular necrosis_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0004154I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn
• renal cast_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0011402I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn
• podocyte foot process effacement_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0008140I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn
• abnormal renal tubule morphology_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0002703I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn
• increased urine protein level_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0002962I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn
• increased circulating cholesterol level_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0005178I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn
• abnormal kidney morphology_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0002135I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn
• increased circulating creatinine level_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0005553I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn
• dilated renal tubules_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0002705I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn
• abnormal renal glomerulus morphology_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0005325I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn
• albuminuria_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0002871I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn
• renal tubule atrophy_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0011346I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn
• podocyte hypertrophy_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0011871I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn
• increased systemic arterial systolic blood pressure_Nphs2<tm1Antc>/Nphs2<tm3.1Antc>,Tg(CAG-cre/Esr1*)86Lbgn/0
  http://metadb.riken.jp/0006144I129C57BL6DBANphs2tm1AntcNphs2tm31AntcTgCAGcreEsr186Lbgn0Nphs2tm31AntcNphs2tm1AntcTgCAGcreEsr186Lbgn

class

http://purl.org/net/cito/citesAsAuthority

• Nphs2<tm3.1Antc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4845889

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD10403
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD10403