Hoang. Nguyen, et.al., Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia., Nature genetics, 2009, 41

http://rdf.ncbi.nlm.nih.gov/pubmed/19718027

Hoang. Nguyen, et.al., Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia., Nature genetics, 2009, 41

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tcf3<tm1.1Efu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4413464
• Tg(Krt14-Tcf7l2)1Efu
  http://metadb.riken.jp/db/mgi_rdf/MGI:4413466
• Tg(Krt14-Tcf7l2*)2Efu
  http://metadb.riken.jp/db/mgi_rdf/MGI:4413467
• Tg(Krt14-Tcf7l2*)3Efu
  http://metadb.riken.jp/db/mgi_rdf/MGI:4413469

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal hair follicle morphology_Tcf3<tm1.1Efu>/Tcf3<tm1.1Efu>,Tcf7l2<tm1Cle>/Tcf7l2<tm1Cle>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0000377I129Sv129P2OlaHsdTcf3tm11EfuTcf3tm11EfuTcf7l2tm1CleTcf7l2tm1CleTgKRT14cre1Efu0Tcf3tm11EfuTcf7l2tm1CleTgKRT14cre1Efu
• absent hair follicles_Ctnnb1<tm4Wbm>/Ctnnb1<tm4Wbm>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0000378I129P2OlaHsdCtnnb1tm4WbmCtnnb1tm4WbmTgKRT14cre1Efu0TgKRT14cre1EfuCtnnb1tm4Wbm
• absent hair follicles_Tcf3<tm1.1Efu>/Tcf3<tm1.1Efu>,Tcf7l2<tm1Cle>/Tcf7l2<tm1Cle>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0000378I129Sv129P2OlaHsdTcf3tm11EfuTcf3tm11EfuTcf7l2tm1CleTcf7l2tm1CleTgKRT14cre1Efu0Tcf3tm11EfuTcf7l2tm1CleTgKRT14cre1Efu
• thin skin_Tcf3<tm1.1Efu>/Tcf3<tm1.1Efu>,Tcf7l2<tm1Cle>/Tcf7l2<tm1Cle>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0001199I129Sv129P2OlaHsdTcf3tm11EfuTcf3tm11EfuTcf7l2tm1CleTcf7l2tm1CleTgKRT14cre1Efu0Tcf3tm11EfuTcf7l2tm1CleTgKRT14cre1Efu
• abnormal epidermal layer morphology_Tg(Krt14-Tcf7l2)1Efu/0
  http://metadb.riken.jp/0001216NSTgKrt14Tcf7l21Efu0TgKrt14Tcf7l21Efu
• thin epidermis_Tcf3<tm1.1Efu>/Tcf3<tm1.1Efu>,Tcf7l2<tm1Cle>/Tcf7l2<tm1Cle>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0001218I129Sv129P2OlaHsdTcf3tm11EfuTcf3tm11EfuTcf7l2tm1CleTcf7l2tm1CleTgKRT14cre1Efu0Tcf3tm11EfuTcf7l2tm1CleTgKRT14cre1Efu
他10件を見る
• thick epidermis_Ctnnb1<tm4Wbm>/Ctnnb1<tm4Wbm>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0001219I129P2OlaHsdCtnnb1tm4WbmCtnnb1tm4WbmTgKRT14cre1Efu0TgKRT14cre1EfuCtnnb1tm4Wbm
• abnormal epidermis stratum basale morphology_Tcf3<tm1.1Efu>/Tcf3<tm1.1Efu>,Tcf7l2<tm1Cle>/Tcf7l2<tm1Cle>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0001231I129Sv129P2OlaHsdTcf3tm11EfuTcf3tm11EfuTcf7l2tm1CleTcf7l2tm1CleTgKRT14cre1Efu0Tcf3tm11EfuTcf7l2tm1CleTgKRT14cre1Efu
• absent vibrissae_Tcf3<tm1.1Efu>/Tcf3<tm1.1Efu>,Tcf7l2<tm1Cle>/Tcf7l2<tm1Cle>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0001284I129Sv129P2OlaHsdTcf3tm11EfuTcf3tm11EfuTcf7l2tm1CleTcf7l2tm1CleTgKRT14cre1Efu0Tcf3tm11EfuTcf7l2tm1CleTgKRT14cre1Efu
• eyelids open at birth_Tg(Krt14-Tcf7l2)1Efu/0
  http://metadb.riken.jp/0001302NSTgKrt14Tcf7l21Efu0TgKrt14Tcf7l21Efu
• eyelids open at birth_Tg(Krt14-Tcf7l2*)2Efu/0
  http://metadb.riken.jp/0001302NSTgKrt14Tcf7l22Efu0TgKrt14Tcf7l22Efu
• no abnormal phenotype detected_Tcf3<tm1.1Efu>/Tcf3<tm1.1Efu>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0002169I129SvTcf3tm11EfuTcf3tm11EfuTgKRT14cre1Efu0TgKRT14cre1EfuTcf3tm11Efu
• no abnormal phenotype detected_Tg(Krt14-Tcf7l2*)3Efu/0
  http://metadb.riken.jp/0002169NSTgKrt14Tcf7l23Efu0TgKrt14Tcf7l23Efu
• abnormal skin physiology_Tcf3<tm1.1Efu>/Tcf3<tm1.1Efu>,Tcf7l2<tm1Cle>/Tcf7l2<tm1Cle>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0005501I129Sv129P2OlaHsdTcf3tm11EfuTcf3tm11EfuTcf7l2tm1CleTcf7l2tm1CleTgKRT14cre1Efu0Tcf3tm11EfuTcf7l2tm1CleTgKRT14cre1Efu
• decreased keratinocyte proliferation_Tcf3<tm1.1Efu>/Tcf3<tm1.1Efu>,Tcf7l2<tm1Cle>/Tcf7l2<tm1Cle>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0009584I129Sv129P2OlaHsdTcf3tm11EfuTcf3tm11EfuTcf7l2tm1CleTcf7l2tm1CleTgKRT14cre1Efu0Tcf3tm11EfuTcf7l2tm1CleTgKRT14cre1Efu
• neonatal lethality, complete penetrance_Ctnnb1<tm4Wbm>/Ctnnb1<tm4Wbm>,Tg(KRT14-cre)1Efu/0
  http://metadb.riken.jp/0011087I129P2OlaHsdCtnnb1tm4WbmCtnnb1tm4WbmTgKRT14cre1Efu0TgKRT14cre1EfuCtnnb1tm4Wbm

class

http://purl.org/net/cito/citesAsAuthority

• Tcf3<tm1.1Efu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4413464
• Tg(Krt14-Tcf7l2)1Efu
  http://metadb.riken.jp/db/mgi_rdf/MGI:4413466
• Tg(Krt14-Tcf7l2*)2Efu
  http://metadb.riken.jp/db/mgi_rdf/MGI:4413467
• Tg(Krt14-Tcf7l2*)3Efu
  http://metadb.riken.jp/db/mgi_rdf/MGI:4413469