Tal. Burstyn-Cohen, et.al., Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis., The Journal of clinical investigation, 2009, 119

http://rdf.ncbi.nlm.nih.gov/pubmed/19729839

Tal. Burstyn-Cohen, et.al., Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis., The Journal of clinical investigation, 2009, 119

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pros1<tm1Grl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5499097
• Pros1<tm1.2Grl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5499100

class

http://purl.org/net/cito/citesAsAuthority

• Pros1<tm1Grl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5499097
• Pros1<tm1.2Grl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5499100

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• brain vascular congestion_Pros1<tm1.2Grl>/Pros1<tm1.2Grl>
  http://metadb.riken.jp/0010022I129S1SvImJFVBNPros1tm12GrlPros1tm12GrlPros1tm12Grl
• abnormal brain vasculature morphology_Pros1<tm1.2Grl>/Pros1<tm1.2Grl>
  http://metadb.riken.jp/0004950I129S1SvImJFVBNPros1tm12GrlPros1tm12GrlPros1tm12Grl
• vasculature congestion_Pros1<tm1.2Grl>/Pros1<tm1.2Grl>
  http://metadb.riken.jp/0000255I129S1SvImJFVBNPros1tm12GrlPros1tm12GrlPros1tm12Grl
• abnormal thrombosis_Pros1<tm1.2Grl>/Pros1<tm1.2Grl>
  http://metadb.riken.jp/0005048I129S1SvImJFVBNPros1tm12GrlPros1tm12GrlPros1tm12Grl
• intracranial hemorrhage_Pros1<tm1.2Grl>/Pros1<tm1.2Grl>
  http://metadb.riken.jp/0001915I129S1SvImJFVBNPros1tm12GrlPros1tm12GrlPros1tm12Grl
• increased vascular permeability_Pros1<tm1.2Grl>/Pros1<+>
  http://metadb.riken.jp/0003070I129S1SvImJFVBNPros1tm12GrlPros1Pros1Pros1tm12Grl
• abnormal vitelline vasculature morphology_Pros1<tm1.2Grl>/Pros1<tm1.2Grl>
  http://metadb.riken.jp/0003229I129S1SvImJFVBNPros1tm12GrlPros1tm12GrlPros1tm12Grl
• abnormal neocortex morphology_Pros1<tm1.2Grl>/Pros1<tm1.2Grl>
  http://metadb.riken.jp/0008547I129S1SvImJFVBNPros1tm12GrlPros1tm12GrlPros1tm12Grl
• increased vascular permeability_Pros1<tm1Grl>/Pros1<tm1Grl>,Tg(Tagln-cre)1Her/0
  http://metadb.riken.jp/0003070I129S1SvImJC57BL6SJLPros1tm1GrlPros1tm1GrlTgTaglncre1Her0Pros1tm1GrlTgTaglncre1Her
• abnormal blood vessel morphology_Pros1<tm1.2Grl>/Pros1<tm1.2Grl>
  http://metadb.riken.jp/0001614I129S1SvImJFVBNPros1tm12GrlPros1tm12GrlPros1tm12Grl
• increased vascular permeability_Axl<tm1Grl>/Axl<tm1Grl>
  http://metadb.riken.jp/0003070IC57BL6JAxltm1GrlAxltm1GrlAxltm1Grl
• increased vascular permeability_Gas6<tm1Pec>/Gas6<tm1Pec>
  http://metadb.riken.jp/0003070I129S1Sv129X1SvJGas6tm1PecGas6tm1PecGas6tm1Pec
• enlarged brain ventricles_Pros1<tm1.2Grl>/Pros1<tm1.2Grl>
  http://metadb.riken.jp/0011380I129S1SvImJFVBNPros1tm12GrlPros1tm12GrlPros1tm12Grl
• increased vascular permeability_Pros1<tm1.2Grl>/Pros1<tm1.2Grl>
  http://metadb.riken.jp/0003070I129S1SvImJFVBNPros1tm12GrlPros1tm12GrlPros1tm12Grl
• no abnormal phenotype detected_Pros1<tm1Grl>/Pros1<tm1Grl>
  http://metadb.riken.jp/0002169I129S1SvImJPros1tm1GrlPros1tm1GrlPros1tm1Grl
• decreased bleeding time_Pros1<tm1.2Grl>/Pros1<+>
  http://metadb.riken.jp/0005607I129S1SvImJFVBNPros1tm12GrlPros1Pros1Pros1tm12Grl
• abnormal thrombosis_Pros1<tm1Grl>/Pros1<tm1Grl>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0005048I129S1SvImJC57BL6SJLPros1tm1GrlPros1tm1GrlTgTekcre1Ywa0TgTekcre1YwaPros1tm1Grl
• abnormal thrombosis_Pros1<tm1Grl>/Pros1<tm1Grl>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005048I129S1SvImJC57BL6DBAPros1tm1GrlPros1tm1GrlTgAlbcre21Mgn0TgAlbcre21MgnPros1tm1Grl
• prenatal lethality, incomplete penetrance_Pros1<tm1.2Grl>/Pros1<+>
  http://metadb.riken.jp/0011101I129S1SvImJFVBNPros1tm12GrlPros1Pros1Pros1tm12Grl
• vascular smooth muscle hypoplasia_Pros1<tm1.2Grl>/Pros1<tm1.2Grl>
  http://metadb.riken.jp/0003814I129S1SvImJFVBNPros1tm12GrlPros1tm12GrlPros1tm12Grl
• abnormal blood coagulation_Pros1<tm1.2Grl>/Pros1<tm1.2Grl>
  http://metadb.riken.jp/0002551I129S1SvImJFVBNPros1tm12GrlPros1tm12GrlPros1tm12Grl
• hemorrhage_Pros1<tm1.2Grl>/Pros1<tm1.2Grl>
  http://metadb.riken.jp/0001914I129S1SvImJFVBNPros1tm12GrlPros1tm12GrlPros1tm12Grl
• abnormal blood vessel morphology_Pros1<tm1.2Grl>/Pros1<+>
  http://metadb.riken.jp/0001614I129S1SvImJFVBNPros1tm12GrlPros1Pros1Pros1tm12Grl
• lethality throughout fetal growth and development, complete penetrance_Pros1<tm1.2Grl>/Pros1<tm1.2Grl>
  http://metadb.riken.jp/0011099I129S1SvImJFVBNPros1tm12GrlPros1tm12GrlPros1tm12Grl

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD07123
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD07123