Rebecca. Favaro, et.al., Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh., Nature neuroscience, 2009, 12

http://rdf.ncbi.nlm.nih.gov/pubmed/19734891

Rebecca. Favaro, et.al., Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh., Nature neuroscience, 2009, 12

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Sox2-cre/ERT2)1Skn
  http://metadb.riken.jp/db/mgi_rdf/MGI:4397776
• Sox2<tm4.1Skn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4397705

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Sox2-cre/ERT2)1Skn
  http://metadb.riken.jp/db/mgi_rdf/MGI:4397776
• Sox2<tm4.1Skn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4397705

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal neuron differentiation_Sox2<tm4.1Skn>/Sox2<tm4.1Skn>,Tg(Sox2-cre/ERT2)1Skn/0
  http://metadb.riken.jp/0009937I129S1Sv129S4SvJaeSox2tm41SknSox2tm41SknTgSox2creERT21Skn0TgSox2creERT21SknSox2tm41Skn
• abnormal cerebral cortex morphology_Sox2<tm2Skn>/Sox2<tm4.1Skn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000788EI129SSvC57BL6SJLorI129SSvC57BL6DBA2SJLSox2tm2SknSox2tm41SknTgNescre1Kln0TgNescre1KlnSox2tm41SknSox2tm2Skn
• enlarged lateral ventricles_Sox2<tm2Skn>/Sox2<tm4.1Skn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008535EI129SSvC57BL6SJLorI129SSvC57BL6DBA2SJLSox2tm2SknSox2tm41SknTgNescre1Kln0TgNescre1KlnSox2tm41SknSox2tm2Skn
• loss of hippocampal neurons_Sox2<tm2Skn>/Sox2<tm4.1Skn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003240EI129SSvC57BL6SJLorI129SSvC57BL6DBA2SJLSox2tm2SknSox2tm41SknTgNescre1Kln0TgNescre1KlnSox2tm41SknSox2tm2Skn
• abnormal corpus callosum morphology_Sox2<tm2Skn>/Sox2<tm4.1Skn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000780EI129SSvC57BL6SJLorI129SSvC57BL6DBA2SJLSox2tm2SknSox2tm41SknTgNescre1Kln0TgNescre1KlnSox2tm41SknSox2tm2Skn
• abnormal hippocampus development_Sox2<tm2Skn>/Sox2<tm4.1Skn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000808EI129SSvC57BL6SJLorI129SSvC57BL6DBA2SJLSox2tm2SknSox2tm41SknTgNescre1Kln0TgNescre1KlnSox2tm41SknSox2tm2Skn
• premature death_Sox2<tm2Skn>/Sox2<tm4.1Skn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002083EI129SSvC57BL6SJLorI129SSvC57BL6DBA2SJLSox2tm2SknSox2tm41SknTgNescre1Kln0TgNescre1KlnSox2tm41SknSox2tm2Skn
• small hippocampus_Sox2<tm2Skn>/Sox2<tm4.1Skn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008283EI129SSvC57BL6SJLorI129SSvC57BL6DBA2SJLSox2tm2SknSox2tm41SknTgNescre1Kln0TgNescre1KlnSox2tm41SknSox2tm2Skn
• abnormal dentate gyrus morphology_Sox2<tm2Skn>/Sox2<tm4.1Skn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000812EI129SSvC57BL6SJLorI129SSvC57BL6DBA2SJLSox2tm2SknSox2tm41SknTgNescre1Kln0TgNescre1KlnSox2tm41SknSox2tm2Skn
• absent dentate gyrus_Sox2<tm2Skn>/Sox2<tm4.1Skn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000814EI129SSvC57BL6SJLorI129SSvC57BL6DBA2SJLSox2tm2SknSox2tm41SknTgNescre1Kln0TgNescre1KlnSox2tm41SknSox2tm2Skn
• abnormal neuronal precursor proliferation_Sox2<tm4.1Skn>/Sox2<tm4.1Skn>,Tg(Sox2-cre/ERT2)1Skn/0
  http://metadb.riken.jp/0004948I129S1Sv129S4SvJaeSox2tm41SknSox2tm41SknTgSox2creERT21Skn0TgSox2creERT21SknSox2tm41Skn
• abnormal neuron differentiation_Sox2<tm2Skn>/Sox2<tm4.1Skn>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009937EI129SSvC57BL6SJLorI129SSvC57BL6DBA2SJLSox2tm2SknSox2tm41SknTgNescre1Kln0TgNescre1KlnSox2tm41SknSox2tm2Skn
• abnormal radial glial cell morphology_Sox2<tm4.1Skn>/Sox2<tm4.1Skn>,Tg(Sox2-cre/ERT2)1Skn/0
  http://metadb.riken.jp/0003648I129S1Sv129S4SvJaeSox2tm41SknSox2tm41SknTgSox2creERT21Skn0TgSox2creERT21SknSox2tm41Skn