Fiona. Grueninger, et.al., Phosphorylation of Tau at S422 is enhanced by Abeta in TauPS2APP triple transgenic mice., Neurobiology of disease, 2010, 37

http://rdf.ncbi.nlm.nih.gov/pubmed/19781645

Fiona. Grueninger, et.al., Phosphorylation of Tau at S422 is enhanced by Abeta in TauPS2APP triple transgenic mice., Neurobiology of disease, 2010, 37

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• tau protein deposits_Tg(Thy1-MAPT)183Gotz/0
  http://metadb.riken.jp/0004250B6CgTgThy1MAPT183GotzTgThy1MAPT183Gotz0TgThy1MAPT183Gotz
• amyloid beta deposits_Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz/0
  http://metadb.riken.jp/0003329C57BL6TgThy1APPSwePrnpPSEN2N141I152HLaozTgThy1APPSwePrnpPSEN2N141I152HLaoz0TgThy1APPSwePrnpPSEN2N141I152HLaoz
• abnormal spatial learning_Tg(Thy1-MAPT)183Gotz/0
  http://metadb.riken.jp/0001463B6CgTgThy1MAPT183GotzTgThy1MAPT183Gotz0TgThy1MAPT183Gotz
• tau protein deposits_Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz/0,Tg(Thy1-MAPT)183Gotz/0
  http://metadb.riken.jp/0004250B6CgTgThy1APPSwePrnpPSEN2N141I152HLaozTgThy1MAPT183GotzTgThy1APPSwePrnpPSEN2N141I152HLaoz0TgThy1MAPT183Gotz0TgThy1APPSwePrnpPSEN2N141I152HLaozTgThy1MAPT183Gotz
• abnormal spatial learning_Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz/0,Tg(Thy1-MAPT)183Gotz/0
  http://metadb.riken.jp/0001463B6CgTgThy1APPSwePrnpPSEN2N141I152HLaozTgThy1MAPT183GotzTgThy1APPSwePrnpPSEN2N141I152HLaoz0TgThy1MAPT183Gotz0TgThy1APPSwePrnpPSEN2N141I152HLaozTgThy1MAPT183Gotz
• abnormal spatial learning_Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz/0
  http://metadb.riken.jp/0001463C57BL6TgThy1APPSwePrnpPSEN2N141I152HLaozTgThy1APPSwePrnpPSEN2N141I152HLaoz0TgThy1APPSwePrnpPSEN2N141I152HLaoz
• increased body weight_Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz/0
  http://metadb.riken.jp/0001260C57BL6TgThy1APPSwePrnpPSEN2N141I152HLaozTgThy1APPSwePrnpPSEN2N141I152HLaoz0TgThy1APPSwePrnpPSEN2N141I152HLaoz
• enhanced coordination_Tg(Thy1-MAPT)183Gotz/0
  http://metadb.riken.jp/0003858B6CgTgThy1MAPT183GotzTgThy1MAPT183Gotz0TgThy1MAPT183Gotz
• impaired coordination_Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz/0
  http://metadb.riken.jp/0001405C57BL6TgThy1APPSwePrnpPSEN2N141I152HLaozTgThy1APPSwePrnpPSEN2N141I152HLaoz0TgThy1APPSwePrnpPSEN2N141I152HLaoz
• amyloid beta deposits_Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz/0,Tg(Thy1-MAPT)183Gotz/0
  http://metadb.riken.jp/0003329B6CgTgThy1APPSwePrnpPSEN2N141I152HLaozTgThy1MAPT183GotzTgThy1APPSwePrnpPSEN2N141I152HLaoz0TgThy1MAPT183Gotz0TgThy1APPSwePrnpPSEN2N141I152HLaozTgThy1MAPT183Gotz
• hyperactivity_Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz/0,Tg(Thy1-MAPT)183Gotz/0
  http://metadb.riken.jp/0001399B6CgTgThy1APPSwePrnpPSEN2N141I152HLaozTgThy1MAPT183GotzTgThy1APPSwePrnpPSEN2N141I152HLaoz0TgThy1MAPT183Gotz0TgThy1APPSwePrnpPSEN2N141I152HLaozTgThy1MAPT183Gotz