Sangphil. Oh, et.al., Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse., Molecular and cellular biology, 2009, 29

http://rdf.ncbi.nlm.nih.gov/pubmed/19786569

Sangphil. Oh, et.al., Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse., Molecular and cellular biology, 2009, 29

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Stk4<tm1Dlim>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4414818
• Stk3<tm1Dlim>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4414809

class

http://purl.org/net/cito/citesAsAuthority

• Stk4<tm1Dlim>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4414818
• Stk3<tm1Dlim>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4414809

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• no abnormal phenotype detected_Stk3<tm1Dlim>/Stk3<tm1Dlim>
  http://metadb.riken.jp/0002169NSStk3tm1DlimStk3tm1DlimStk3tm1Dlim
• abnormal vascular branching morphogenesis_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0003227NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• embryonic lethality during organogenesis, complete penetrance_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0011098NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• increased embryonic tissue cell apoptosis_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0013504NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• abnormal neural plate morphology_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0005657NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• decreased trophoblast giant cell number_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0001713NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• increased placenta apoptosis_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0009658NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• abnormal vitelline vasculature morphology_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0003229NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• decreased T cell number_Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0005018NSStk4tm1DlimStk4tm1DlimStk4tm1Dlim
• abnormal heart development_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0000267NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• small ectoplacental cone_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0002584NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• abnormal placental transport_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0004265NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• abnormal placental labyrinth vasculature morphology_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0008803NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• abnormal vascular endothelial cell morphology_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0006055NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• incomplete embryo turning_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0001701NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• abnormal embryo development_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0001672NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• abnormal placenta development_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0001712NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• abnormal T cell physiology_Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0002444NSStk4tm1DlimStk4tm1DlimStk4tm1Dlim
• embryonic growth retardation_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0003984NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• abnormal chorion morphology_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0002836NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• abnormal embryonic hematopoiesis_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0003396NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• abnormal cell proliferation_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0000350NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• abnormal angiogenesis_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0000260NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• abnormal placenta labyrinth morphology_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0001716NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• decreased embryo size_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0001698NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• abnormal blood vessel morphology_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0001614NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim
• abnormal embryonic neuroepithelium morphology_Stk3<tm1Dlim>/Stk3<tm1Dlim>,Stk4<tm1Dlim>/Stk4<tm1Dlim>
  http://metadb.riken.jp/0004261NSStk3tm1DlimStk3tm1DlimStk4tm1DlimStk4tm1DlimStk3tm1DlimStk4tm1Dlim

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD28789
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD28789
• CD10746
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD10746
• CD10866
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD10866
• CD15198
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15198
• CD11791
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD11791