Tina M. Albertson, et.al., DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106

http://rdf.ncbi.nlm.nih.gov/pubmed/19805137

Tina M. Albertson, et.al., DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pole<tm1.1Bdp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4366913
• Pold1<tm1.1Bdp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4458032

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• enlarged spleen_Pole<tm1.1Bdp>/Pole<tm1.1Bdp>
  http://metadb.riken.jp/0000691B6129Poletm11BdpPoletm11BdpPoletm11BdpPoletm11Bdp
• increased tumor incidence_Pole<tm1.1Bdp>/Pole<tm1.1Bdp>
  http://metadb.riken.jp/0002020I129S1Sv129X1SvJC57BL6JPoletm11BdpPoletm11BdpPoletm11Bdp
• increased T cell derived lymphoma incidence_Pold1<tm1.1Bdp>/Pold1<tm1.1Bdp>
  http://metadb.riken.jp/0002024B6129Pold1tm11BdpPold1tm11BdpPold1tm11BdpPold1tm11Bdp
• increased T cell derived lymphoma incidence_Pold1<tm1.1Bdp>/Pold1<tm1.1Bdp>,Pole<tm1.1Bdp>/Pole<tm1.1Bdp>
  http://metadb.riken.jp/0002024B6129Poletm11BdpPold1tm11BdpPold1tm11BdpPold1tm11BdpPoletm11BdpPoletm11BdpPold1tm11BdpPoletm11Bdp
• increased T cell derived lymphoma incidence_Mlh1<tm1Rak>/Mlh1<tm1Rak>
  http://metadb.riken.jp/0002024I129P2OlaHsdC57BL6C57BL6JMlh1tm1RakMlh1tm1RakMlh1tm1Rak
• premature death_Pold1<tm1.1Bdp>/Pold1<tm1.1Bdp>
  http://metadb.riken.jp/0002083B6129Pold1tm11BdpPold1tm11BdpPold1tm11BdpPold1tm11Bdp
他25件を見る
• premature death_Pold1<tm1.1Bdp>/Pold1<tm1.1Bdp>,Pole<tm1.1Bdp>/Pole<tm1.1Bdp>
  http://metadb.riken.jp/0002083B6129Poletm11BdpPold1tm11BdpPold1tm11BdpPold1tm11BdpPoletm11BdpPoletm11BdpPold1tm11BdpPoletm11Bdp
• premature death_Pole<tm1.1Bdp>/Pole<tm1.1Bdp>
  http://metadb.riken.jp/0002083B6129Poletm11BdpPoletm11BdpPoletm11BdpPoletm11Bdp
• premature death_Mlh1<tm1Rak>/Mlh1<tm1Rak>
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6C57BL6JMlh1tm1RakMlh1tm1RakMlh1tm1Rak
• premature death_Pole<tm1.1Bdp>/Pole<tm1.1Bdp>
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJC57BL6JPoletm11BdpPoletm11BdpPoletm11Bdp
• increased intestinal adenoma incidence_Pold1<tm1.1Bdp>/Pold1<tm1.1Bdp>
  http://metadb.riken.jp/0002404B6129Pold1tm11BdpPold1tm11BdpPold1tm11BdpPold1tm11Bdp
• increased intestinal adenoma incidence_Pole<tm1.1Bdp>/Pole<tm1.1Bdp>
  http://metadb.riken.jp/0002404B6129Poletm11BdpPoletm11BdpPoletm11BdpPoletm11Bdp
• increased intestinal adenoma incidence_Mlh1<tm1Rak>/Mlh1<tm1Rak>
  http://metadb.riken.jp/0002404I129P2OlaHsdC57BL6C57BL6JMlh1tm1RakMlh1tm1RakMlh1tm1Rak
• increased intestinal adenocarcinoma incidence_Pold1<tm1.1Bdp>/Pold1<tm1.1Bdp>
  http://metadb.riken.jp/0002957B6129Pold1tm11BdpPold1tm11BdpPold1tm11BdpPold1tm11Bdp
• increased intestinal adenocarcinoma incidence_Pole<tm1.1Bdp>/Pole<tm1.1Bdp>
  http://metadb.riken.jp/0002957B6129Poletm11BdpPoletm11BdpPoletm11BdpPoletm11Bdp
• increased intestinal adenocarcinoma incidence_Mlh1<tm1Rak>/Mlh1<tm1Rak>
  http://metadb.riken.jp/0002957I129P2OlaHsdC57BL6C57BL6JMlh1tm1RakMlh1tm1RakMlh1tm1Rak
• increased lung tumor incidence_Pold1<tm1.1Bdp>/Pold1<tm1.1Bdp>
  http://metadb.riken.jp/0008014B6129Pold1tm11BdpPold1tm11BdpPold1tm11BdpPold1tm11Bdp
• increased lung tumor incidence_Pole<tm1.1Bdp>/Pole<tm1.1Bdp>
  http://metadb.riken.jp/0008014B6129Poletm11BdpPoletm11BdpPoletm11BdpPoletm11Bdp
• increased small intestine adenocarcinoma incidence_Pole<tm1.1Bdp>/Pole<tm1.1Bdp>
  http://metadb.riken.jp/0009309B6129Poletm11BdpPoletm11BdpPoletm11BdpPoletm11Bdp
• increased colon adenocarcinoma incidence_Pole<tm1.1Bdp>/Pole<tm1.1Bdp>
  http://metadb.riken.jp/0009314B6129Poletm11BdpPoletm11BdpPoletm11BdpPoletm11Bdp
• increased histiocytic sarcoma incidence_Pole<tm1.1Bdp>/Pole<tm1.1Bdp>
  http://metadb.riken.jp/0009321B6129Poletm11BdpPoletm11BdpPoletm11BdpPoletm11Bdp
• increased skin tumor incidence_Pold1<tm1.1Bdp>/Pold1<tm1.1Bdp>
  http://metadb.riken.jp/0010300B6129Pold1tm11BdpPold1tm11BdpPold1tm11BdpPold1tm11Bdp
• increased skin tumor incidence_Pold1<tm1.1Bdp>/Pold1<tm1.1Bdp>,Pole<tm1.1Bdp>/Pole<tm1.1Bdp>
  http://metadb.riken.jp/0010300B6129Poletm11BdpPold1tm11BdpPold1tm11BdpPold1tm11BdpPoletm11BdpPoletm11BdpPold1tm11BdpPoletm11Bdp
• increased adenoma incidence_Pole<tm1.1Bdp>/Pole<tm1.1Bdp>
  http://metadb.riken.jp/0010383B6129Poletm11BdpPoletm11BdpPoletm11BdpPoletm11Bdp
• postnatal lethality, complete penetrance_Msh2<tm1Rak>/Msh2<tm1Rak>,Pold1<tm1.1Bdp>/Pold1<tm1.1Bdp>
  http://metadb.riken.jp/0011085I129P2OlaHsd129S1Sv129X1SvJC57BL6C57BL6JMsh2tm1RakMsh2tm1RakPold1tm11BdpPold1tm11BdpMsh2tm1RakPold1tm11Bdp
• postnatal lethality, complete penetrance_Msh2<tm1Rak>/Msh2<tm1Rak>,Pole<tm1.1Bdp>/Pole<tm1.1Bdp>
  http://metadb.riken.jp/0011085I129P2OlaHsd129S1Sv129X1SvJC57BL6C57BL6JMsh2tm1RakMsh2tm1RakPoletm11BdpPoletm11BdpPoletm11BdpMsh2tm1Rak
• embryonic lethality during organogenesis, complete penetrance_Mlh1<tm1Rak>/Mlh1<tm1Rak>,Pold1<tm1.1Bdp>/Pold1<tm1.1Bdp>
  http://metadb.riken.jp/0011098I129P2OlaHsd129S1Sv129X1SvJC57BL6C57BL6JMlh1tm1RakMlh1tm1RakPold1tm11BdpPold1tm11BdpPold1tm11BdpMlh1tm1Rak
• lethality during fetal growth through weaning, complete penetrance_Mlh1<tm1Rak>/Mlh1<tm1Rak>,Pole<tm1.1Bdp>/Pole<tm1.1Bdp>
  http://metadb.riken.jp/0011111I129P2OlaHsd129S1Sv129X1SvJC57BL6C57BL6JMlh1tm1RakMlh1tm1RakPoletm11BdpPoletm11BdpPoletm11BdpMlh1tm1Rak
• increased lymphoma incidence_Pold1<tm1.1Bdp>/Pold1<tm1.1Bdp>
  http://metadb.riken.jp/0012431B6129Pold1tm11BdpPold1tm11BdpPold1tm11BdpPold1tm11Bdp
• increased lymphoma incidence_Pole<tm1.1Bdp>/Pole<tm1.1Bdp>
  http://metadb.riken.jp/0012431B6129Poletm11BdpPoletm11BdpPoletm11BdpPoletm11Bdp
• increased lymphoma incidence_Mlh1<tm1Rak>/Mlh1<tm1Rak>
  http://metadb.riken.jp/0012431I129P2OlaHsdC57BL6C57BL6JMlh1tm1RakMlh1tm1RakMlh1tm1Rak

class

http://purl.org/net/cito/citesAsAuthority

• Pole<tm1.1Bdp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4366913
• Pold1<tm1.1Bdp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4458032

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD11778
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD11778
• CD12010
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12010
• CD15898
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15898