Iga. Wegorzewska, et.al., TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106

http://rdf.ncbi.nlm.nih.gov/pubmed/19833869

Iga. Wegorzewska, et.al., TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Prnp-TARDBP*A315T)95Balo
  http://metadb.riken.jp/db/mgi_rdf/MGI:4358722

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Prnp-TARDBP*A315T)95Balo
  http://metadb.riken.jp/db/mgi_rdf/MGI:4358722

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal skeletal muscle morphology_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0000759IC57BL6CBATgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• motor neuron degeneration_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0000938IC57BL6CBATgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• abnormal skeletal muscle fiber morphology_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0003084IC57BL6CBATgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• muscle weakness_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0000747IC57BL6CBATgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• abnormal gait_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0001406IC57BL6CBATgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• abnormal spinal cord ventral horn morphology_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0005112IC57BL6CBATgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• astrocytosis_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0003354IC57BL6CBATgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• premature death_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0002083IC57BL6CBATgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• weight loss_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0001263IC57BL6CBATgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• abnormal neuron morphology_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0002882IC57BL6CBATgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• decreased motor neuron number_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0000939IC57BL6CBATgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• abnormal spinal cord morphology_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0000955IC57BL6CBATgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• abnormal muscle electrophysiology_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0004145IC57BL6CBATgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo
• neuron degeneration_Tg(Prnp-TARDBP*A315T)95Balo/0
  http://metadb.riken.jp/0003224IC57BL6CBATgPrnpTARDBPA315T95Balo0TgPrnpTARDBPA315T95Balo