Victoria. Randall, et.al., Great vessel development requires biallelic expression of Chd7 and Tbx1 in pharyngeal ectoderm in mice., The Journal of clinical investigation, 2009, 119

http://rdf.ncbi.nlm.nih.gov/pubmed/19855134

Victoria. Randall, et.al., Great vessel development requires biallelic expression of Chd7 and Tbx1 in pharyngeal ectoderm in mice., The Journal of clinical investigation, 2009, 119

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal lateral semicircular canal morphology_Tbx1<tm1Bld>/Tbx1<+>
  http://metadb.riken.jp/0000037B6129S7Tbx1tm1BldTbx1tm1BldTbx1Tbx1tm1BldTbx1
• abnormal lateral semicircular canal morphology_Chd7<Whi>/Chd7<+>
  http://metadb.riken.jp/0000037B6C3FeChd7WhiChd7WhiChd7Chd7Chd7Whi
• abnormal lateral semicircular canal morphology_Chd7<Whi>/Chd7<+>,Tbx1<tm1Bld>/Tbx1<+>
  http://metadb.riken.jp/0000037B6CgChd7WhiTbx1tm1BldChd7WhiChd7Tbx1tm1BldTbx1Tbx1tm1BldTbx1Chd7WhiChd7
• cleft palate_Tbx1<tm1Bld>/Tbx1<tm2.1Bem>,Tfap2a<tm1(cre)Moon>/Tfap2a<+>
  http://metadb.riken.jp/0000111EI129SvC57BL6SJLorI129SvC57BL6JCBASJLTbx1tm1BldTbx1tm21BemTfap2atm1creMoonTfap2aTfap2aTbx1tm21BemTfap2atm1creMoonTbx1tm1Bld
• abnormal pulmonary trunk morphology_Chd7<Gt(XK403)Byg>/Chd7<+>
  http://metadb.riken.jp/0000486I129P2OlaHsdC57BL6Chd7GtXK403BygChd7Chd7GtXK403BygChd7
• athymia_Tbx1<tm1Bld>/Tbx1<tm2.1Bem>,Tfap2a<tm1(cre)Moon>/Tfap2a<+>
  http://metadb.riken.jp/0000705EI129SvC57BL6SJLorI129SvC57BL6JCBASJLTbx1tm1BldTbx1tm21BemTfap2atm1creMoonTfap2aTfap2aTbx1tm21BemTfap2atm1creMoonTbx1tm1Bld
他51件を見る
• small thymus_Chd7<Gt(RRR136)Byg>/Chd7<+>
  http://metadb.riken.jp/0000706I129P2OlaHsdC57BL6Chd7GtRRR136BygChd7Chd7GtRRR136BygChd7
• abnormal cranial nerve morphology_Chd7<Gt(XK403)Byg>/Chd7<+>
  http://metadb.riken.jp/0001056I129P2OlaHsdC57BL6Chd7GtXK403BygChd7Chd7GtXK403BygChd7
• abnormal vagus nerve morphology_Chd7<Gt(XK403)Byg>/Chd7<+>
  http://metadb.riken.jp/0001074I129P2OlaHsdC57BL6Chd7GtXK403BygChd7Chd7GtXK403BygChd7
• circling_Chd7<Gt(RRR136)Byg>/Chd7<+>
  http://metadb.riken.jp/0001394I129P2OlaHsdC57BL6Chd7GtRRR136BygChd7Chd7GtRRR136BygChd7
• circling_Chd7<Gt(XK403)Byg>/Chd7<+>
  http://metadb.riken.jp/0001394I129P2OlaHsdC57BL6Chd7GtXK403BygChd7Chd7GtXK403BygChd7
• thymus hypoplasia_Tbx1<tm1Bld>/Tbx1<tm2.1Bem>,Tfap2a<tm1(cre)Moon>/Tfap2a<+>
  http://metadb.riken.jp/0001823EI129SvC57BL6SJLorI129SvC57BL6JCBASJLTbx1tm1BldTbx1tm21BemTfap2atm1creMoonTfap2aTfap2aTbx1tm21BemTfap2atm1creMoonTbx1tm1Bld
• thymus hypoplasia_Chd7<Gt(RRR136)Byg>/Chd7<+>
  http://metadb.riken.jp/0001823I129P2OlaHsdC57BL6Chd7GtRRR136BygChd7Chd7GtRRR136BygChd7
• no abnormal phenotype detected_Tbx1<tm2.1Bem>/Tbx1<tm2.1Bem>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0002169EI129SvC57BL6C57BL6JCBAJSJLorI129SvC57BL6JCBAJCD1SJLTbx1tm21BemTbx1tm21BemTgWnt1cre11Rth0TgWnt1cre11RthTbx1tm21Bem
• persistent truncus arteriosis_Tbx1<tm1Bld>/Tbx1<tm2.1Bem>,Tfap2a<tm1(cre)Moon>/Tfap2a<+>
  http://metadb.riken.jp/0002633EI129SvC57BL6SJLorI129SvC57BL6JCBASJLTbx1tm1BldTbx1tm21BemTfap2atm1creMoonTfap2aTfap2aTbx1tm21BemTfap2atm1creMoonTbx1tm1Bld
• abnormal pharyngeal arch artery morphology_Chd7<Gt(RRR136)Byg>/Chd7<+>
  http://metadb.riken.jp/0002672I129P2OlaHsdC57BL6Chd7GtRRR136BygChd7Chd7GtRRR136BygChd7
• abnormal pharyngeal arch artery morphology_Chd7<Gt(XK403)Byg>/Chd7<+>
  http://metadb.riken.jp/0002672I129P2OlaHsdC57BL6Chd7GtXK403BygChd7Chd7GtXK403BygChd7
• abnormal posterior semicircular canal morphology_Chd7<Whi>/Chd7<+>
  http://metadb.riken.jp/0002858B6C3FeChd7WhiChd7WhiChd7Chd7Chd7Whi
• abnormal posterior semicircular canal morphology_Chd7<Whi>/Chd7<+>,Tbx1<tm1Bld>/Tbx1<+>
  http://metadb.riken.jp/0002858B6CgChd7WhiTbx1tm1BldChd7WhiChd7Tbx1tm1BldTbx1Tbx1tm1BldTbx1Chd7WhiChd7
• abnormal neural crest cell migration_Chd7<Gt(XK403)Byg>/Chd7<+>
  http://metadb.riken.jp/0002950I129P2OlaHsdC57BL6Chd7GtXK403BygChd7Chd7GtXK403BygChd7
• ectopic thymus_Chd7<Gt(XK403)Byg>/Chd7<+>,Tbx1<tm1Bld>/Tbx1<+>
  http://metadb.riken.jp/0003007EI129P2OlaHsd129S7SvEvBrdC57BL6orI129P2OlaHsd129S7SvEvBrdC57BL6CD1Chd7GtXK403BygChd7Tbx1tm1BldTbx1Tbx1tm1BldTbx1Chd7GtXK403BygChd7
• ectopic thymus_Chd7<Gt(RRR136)Byg>/Chd7<+>
  http://metadb.riken.jp/0003007I129P2OlaHsdC57BL6Chd7GtRRR136BygChd7Chd7GtRRR136BygChd7
• absent lateral semicircular canal_Tbx1<tm1Bld>/Tbx1<+>
  http://metadb.riken.jp/0003161B6129S7Tbx1tm1BldTbx1tm1BldTbx1Tbx1tm1BldTbx1
• absent lateral semicircular canal_Chd7<Whi>/Chd7<+>
  http://metadb.riken.jp/0003161B6C3FeChd7WhiChd7WhiChd7Chd7Chd7Whi
• absent lateral semicircular canal_Chd7<Whi>/Chd7<+>,Tbx1<tm1Bld>/Tbx1<+>
  http://metadb.riken.jp/0003161B6CgChd7WhiTbx1tm1BldChd7WhiChd7Tbx1tm1BldTbx1Tbx1tm1BldTbx1Chd7WhiChd7
• aorta coarctation_Chd7<Gt(XK403)Byg>/Chd7<+>
  http://metadb.riken.jp/0003387I129P2OlaHsdC57BL6Chd7GtXK403BygChd7Chd7GtXK403BygChd7
• abnormal subclavian artery morphology_Chd7<Gt(XK403)Byg>/Chd7<+>,Tbx1<tm1Bld>/Tbx1<+>
  http://metadb.riken.jp/0003395EI129P2OlaHsd129S7SvEvBrdC57BL6orI129P2OlaHsd129S7SvEvBrdC57BL6CD1Chd7GtXK403BygChd7Tbx1tm1BldTbx1Tbx1tm1BldTbx1Chd7GtXK403BygChd7
• abnormal subclavian artery morphology_Chd7<Gt(XK403)Byg>/Chd7<+>
  http://metadb.riken.jp/0003395I129P2OlaHsdC57BL6Chd7GtXK403BygChd7Chd7GtXK403BygChd7
• abnormal ear development_Chd7<Gt(XK403)Byg>/Chd7<+>,Tbx1<tm1Bld>/Tbx1<+>
  http://metadb.riken.jp/0003938EI129P2OlaHsd129S7SvEvBrdC57BL6orI129P2OlaHsd129S7SvEvBrdC57BL6CD1Chd7GtXK403BygChd7Tbx1tm1BldTbx1Tbx1tm1BldTbx1Chd7GtXK403BygChd7
• abnormal aortic arch morphology_Tbx1<tm1Bld>/Tbx1<tm2.1Bem>,Tfap2a<tm1(cre)Moon>/Tfap2a<+>
  http://metadb.riken.jp/0004113EI129SvC57BL6SJLorI129SvC57BL6JCBASJLTbx1tm1BldTbx1tm21BemTfap2atm1creMoonTfap2aTfap2aTbx1tm21BemTfap2atm1creMoonTbx1tm1Bld
• interrupted aortic arch_Chd7<Gt(XK403)Byg>/Chd7<+>,Tbx1<tm1Bld>/Tbx1<+>
  http://metadb.riken.jp/0004157EI129P2OlaHsd129S7SvEvBrdC57BL6orI129P2OlaHsd129S7SvEvBrdC57BL6CD1Chd7GtXK403BygChd7Tbx1tm1BldTbx1Tbx1tm1BldTbx1Chd7GtXK403BygChd7
• interrupted aortic arch_Chd7<Gt(XK403)Byg>/Chd7<+>
  http://metadb.riken.jp/0004157I129P2OlaHsdC57BL6Chd7GtXK403BygChd7Chd7GtXK403BygChd7
• fusion of glossopharyngeal and vagus nerve_Chd7<Gt(XK403)Byg>/Chd7<+>
  http://metadb.riken.jp/0004568I129P2OlaHsdC57BL6Chd7GtXK403BygChd7Chd7GtXK403BygChd7
• abnormal cardiac outflow tract development_Tbx1<tm1Bld>/Tbx1<tm2.1Bem>,Tfap2a<tm1(cre)Moon>/Tfap2a<+>
  http://metadb.riken.jp/0006126EI129SvC57BL6SJLorI129SvC57BL6JCBASJLTbx1tm1BldTbx1tm21BemTfap2atm1creMoonTfap2aTfap2aTbx1tm21BemTfap2atm1creMoonTbx1tm1Bld
• abnormal cardiac outflow tract development_Chd7<Gt(RRR136)Byg>/Chd7<+>
  http://metadb.riken.jp/0006126I129P2OlaHsdC57BL6Chd7GtRRR136BygChd7Chd7GtRRR136BygChd7
• abnormal cardiac outflow tract development_Chd7<Gt(XK403)Byg>/Chd7<+>
  http://metadb.riken.jp/0006126I129P2OlaHsdC57BL6Chd7GtXK403BygChd7Chd7GtXK403BygChd7
• abnormal fourth pharyngeal arch artery morphology_Chd7<Gt(XK403)Byg>/Chd7<+>,Tbx1<tm1Bld>/Tbx1<+>
  http://metadb.riken.jp/0006354EI129P2OlaHsd129S7SvEvBrdC57BL6orI129P2OlaHsd129S7SvEvBrdC57BL6CD1Chd7GtXK403BygChd7Tbx1tm1BldTbx1Tbx1tm1BldTbx1Chd7GtXK403BygChd7
• abnormal fourth pharyngeal arch artery morphology_Chd7<Gt(XK403)Byg>/Chd7<+>,Tg(Wnt1-cre)11Rth/0
  http://metadb.riken.jp/0006354EI129P2OlaHsdC57BL6C57BL6JCBAJorI129P2OlaHsdC57BL6JCBAJCD1Chd7GtXK403BygChd7TgWnt1cre11Rth0Chd7Chd7GtXK403BygTgWnt1cre11Rth
• abnormal fourth pharyngeal arch artery morphology_Chd7<Gt(XK403)Byg>/Chd7<+>,Mesp1<tm2(cre)Ysa>/Mesp1<+>
  http://metadb.riken.jp/0006354EI129P2OlaHsdC57BL6CBAorI129P2OlaHsdC57BL6CBACD1Chd7GtXK403BygChd7Mesp1tm2creYsaMesp1Chd7GtXK403BygMesp1tm2creYsaChd7Mesp1
• abnormal fourth pharyngeal arch artery morphology_Chd7<Gt(XK403)Byg>/Chd7<+>
  http://metadb.riken.jp/0006354EI129P2OlaHsdC57BL6orI129P2OlaHsdCD1Chd7GtXK403BygChd7Chd7GtXK403BygChd7
• abnormal fourth pharyngeal arch artery morphology_Chd7<Gt(XK403)Byg>/Chd7<+>,Fgf8<tm1.2Mrt>/Fgf8<+>
  http://metadb.riken.jp/0006354EI129P2OlaHsdC57BL6orI129P2OlaHsdCD1Chd7GtXK403BygChd7Fgf8tm12MrtFgf8Chd7Chd7GtXK403BygFgf8tm12MrtFgf8
• abnormal fourth pharyngeal arch artery morphology_Chd7<Gt(XK403)Byg>/Chd7<+>,Tg(Tbx1-cre)1Joe/0
  http://metadb.riken.jp/0006354EI129P2OlaHsdC57BL6orI129P2OlaHsdCD1Chd7GtXK403BygChd7TgTbx1cre1Joe0TgTbx1cre1JoeChd7GtXK403BygChd7
• abnormal fourth pharyngeal arch artery morphology_Tbx1<tm2.1Bem>/Tbx1<+>,Tfap2a<tm1(cre)Moon>/Tfap2a<+>
  http://metadb.riken.jp/0006354EI129SvC57BL6C57BL6JSJLorI129SvC57BL6JCBASJLTbx1tm21BemTbx1Tfap2atm1creMoonTfap2aTbx1Tfap2atm1creMoonTbx1tm21BemTfap2a
• abnormal fourth pharyngeal arch artery morphology_Chd7<Gt(RRR136)Byg>/Chd7<+>
  http://metadb.riken.jp/0006354I129P2OlaHsdC57BL6Chd7GtRRR136BygChd7Chd7GtRRR136BygChd7
• abnormal fourth pharyngeal arch artery morphology_Chd7<Gt(XK403)Byg>/Chd7<+>
  http://metadb.riken.jp/0006354I129P2OlaHsdC57BL6Chd7GtXK403BygChd7Chd7GtXK403BygChd7
• abnormal sixth pharyngeal arch artery morphology_Chd7<Gt(XK403)Byg>/Chd7<+>,Mesp1<tm2(cre)Ysa>/Mesp1<+>
  http://metadb.riken.jp/0006355EI129P2OlaHsdC57BL6CBAorI129P2OlaHsdC57BL6CBACD1Chd7GtXK403BygChd7Mesp1tm2creYsaMesp1Chd7GtXK403BygMesp1tm2creYsaChd7Mesp1
• abnormal sixth pharyngeal arch artery morphology_Chd7<Gt(XK403)Byg>/Chd7<+>,Tg(Tbx1-cre)1Joe/0
  http://metadb.riken.jp/0006355EI129P2OlaHsdC57BL6orI129P2OlaHsdCD1Chd7GtXK403BygChd7TgTbx1cre1Joe0TgTbx1cre1JoeChd7GtXK403BygChd7
• abnormal sixth pharyngeal arch artery morphology_Chd7<Gt(RRR136)Byg>/Chd7<+>
  http://metadb.riken.jp/0006355I129P2OlaHsdC57BL6Chd7GtRRR136BygChd7Chd7GtRRR136BygChd7
• abnormal sixth pharyngeal arch artery morphology_Chd7<Gt(XK403)Byg>/Chd7<+>
  http://metadb.riken.jp/0006355I129P2OlaHsdC57BL6Chd7GtXK403BygChd7Chd7GtXK403BygChd7
• ventricular septal defect_Tbx1<tm1Bld>/Tbx1<tm2.1Bem>,Tfap2a<tm1(cre)Moon>/Tfap2a<+>
  http://metadb.riken.jp/0010402EI129SvC57BL6SJLorI129SvC57BL6JCBASJLTbx1tm1BldTbx1tm21BemTfap2atm1creMoonTfap2aTfap2aTbx1tm21BemTfap2atm1creMoonTbx1tm1Bld
• aberrant origin of the right subclavian artery_Tbx1<tm1Bld>/Tbx1<tm2.1Bem>,Tfap2a<tm1(cre)Moon>/Tfap2a<+>
  http://metadb.riken.jp/0010465EI129SvC57BL6SJLorI129SvC57BL6JCBASJLTbx1tm1BldTbx1tm21BemTfap2atm1creMoonTfap2aTfap2aTbx1tm21BemTfap2atm1creMoonTbx1tm1Bld
• aortic arch coarctation_Chd7<Gt(RRR136)Byg>/Chd7<+>
  http://metadb.riken.jp/0010526I129P2OlaHsdC57BL6Chd7GtRRR136BygChd7Chd7GtRRR136BygChd7
• postnatal lethality, incomplete penetrance_Chd7<Gt(XK403)Byg>/Chd7<+>
  http://metadb.riken.jp/0011086I129P2OlaHsdC57BL6Chd7GtXK403BygChd7Chd7GtXK403BygChd7
• embryonic lethality, complete penetrance_Chd7<Gt(RRR136)Byg>/Chd7<Gt(RRR136)Byg>
  http://metadb.riken.jp/0011092I129P2OlaHsdC57BL6Chd7GtRRR136BygChd7GtRRR136BygChd7GtRRR136Byg
• embryonic lethality, complete penetrance_Chd7<Gt(XK403)Byg>/Chd7<Gt(XK403)Byg>
  http://metadb.riken.jp/0011092I129P2OlaHsdC57BL6Chd7GtXK403BygChd7GtXK403BygChd7GtXK403Byg
• embryonic lethality during organogenesis, incomplete penetrance_Chd7<Gt(XK403)Byg>/Chd7<+>
  http://metadb.riken.jp/0011108I129P2OlaHsdC57BL6Chd7GtXK403BygChd7Chd7GtXK403BygChd7
• abnormal common carotid artery morphology_Chd7<Gt(RRR136)Byg>/Chd7<+>
  http://metadb.riken.jp/0012729I129P2OlaHsdC57BL6Chd7GtRRR136BygChd7Chd7GtRRR136BygChd7

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD08219
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD08219
• CD11866
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD11866

BRC マウスの系統

http://metadb.riken.jp/db/rikenbrc_mouse/publications

• ICR.Cg-Mesp1<tm2(cre)Ysa>/YsaRbrc
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC01145

BRC マウスの系統

http://purl.org/dc/terms/references

• ICR.Cg-Mesp1<tm2(cre)Ysa>/YsaRbrc
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC01145