Fangnian. Wang, et.al., Brd2 disruption in mice causes severe obesity without Type 2 diabetes., The Biochemical journal, 2009, 425

http://rdf.ncbi.nlm.nih.gov/pubmed/19883376

Fangnian. Wang, et.al., Brd2 disruption in mice causes severe obesity without Type 2 diabetes., The Biochemical journal, 2009, 425

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• improved glucose tolerance_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0005292B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• increased fat cell size_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0006094B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• increased circulating triglyceride level_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0001552B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• increased total body fat amount_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0010024B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• increased basal metabolism_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0008965B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• increased circulating insulin level_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0002079B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• increased circulating tumor necrosis factor level_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0008553B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• increased circulating interleukin-1 beta level_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0008641B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• abnormal pancreatic islet morphology_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0005215B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• increased circulating glucagon level_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0002712B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• increased epididymal fat pad weight_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0009288B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• increased pancreatic beta cell number_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0003645B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• increased pancreatic islet number_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0009167B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• increased adiponectin level_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0004892B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• abnormal adipose tissue morphology_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0000003B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• increased circulating cholesterol level_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0005178B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• abnormal circulating lipid level_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0003949B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• increased interscapular fat pad weight_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0009294B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• abnormal eating behavior_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0001431B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• hepatic steatosis_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0002628B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• perinatal lethality, incomplete penetrance_Brd2<Gt(RRT234)Byg>/Brd2<Gt(RRT234)Byg>
  http://metadb.riken.jp/0011090B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2GtRRT234BygBrd2GtRRT234Byg
• obese_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0001261B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• abnormal blood homeostasis_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0009642B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• decreased circulating glucose level_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0005560B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• increased circulating leptin level_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0005669B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• pancreatic islet hyperplasia_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0005491B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• abnormal respiratory quotient_Brd2<Gt(RRT234)Byg>/Brd2<+>
  http://metadb.riken.jp/0004129B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2Brd2GtRRT234BygBrd2
• postnatal lethality, incomplete penetrance_Brd2<Gt(RRT234)Byg>/Brd2<Gt(RRT234)Byg>
  http://metadb.riken.jp/0011086B6129P2Brd2GtRRT234BygBrd2GtRRT234BygBrd2GtRRT234BygBrd2GtRRT234Byg

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD02647
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02647