Antje. Willuweit, et.al., Early-onset and robust amyloid pathology in a new homozygous mouse model of Alzheimer's disease., PloS one, 2009, 4

http://rdf.ncbi.nlm.nih.gov/pubmed/19936202

Antje. Willuweit, et.al., Early-onset and robust amyloid pathology in a new homozygous mouse model of Alzheimer's disease., PloS one, 2009, 4

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte
  http://metadb.riken.jp/db/mgi_rdf/MGI:4417910

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte
  http://metadb.riken.jp/db/mgi_rdf/MGI:4417910

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• amyloidosis_Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte
  http://metadb.riken.jp/0000604IC57BL6CBATgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10Arte
• increased anxiety-related response_Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte
  http://metadb.riken.jp/0001363IC57BL6CBATgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10Arte
• hypoactivity_Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte
  http://metadb.riken.jp/0001402IC57BL6CBATgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10Arte
• abnormal object recognition memory_Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte
  http://metadb.riken.jp/0001458IC57BL6CBATgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10Arte
• abnormal spatial learning_Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte
  http://metadb.riken.jp/0001463IC57BL6CBATgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10Arte
• premature death_Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte
  http://metadb.riken.jp/0002083IC57BL6CBATgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10Arte
他12件を見る
• amyloid beta deposits_Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/0
  http://metadb.riken.jp/0003329IC57BL6CBATgThy1PSEN1M146VAPPSwe10Arte0TgThy1PSEN1M146VAPPSwe10Arte
• amyloid beta deposits_Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte
  http://metadb.riken.jp/0003329IC57BL6CBATgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10Arte
• astrocytosis_Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/0
  http://metadb.riken.jp/0003354IC57BL6CBATgThy1PSEN1M146VAPPSwe10Arte0TgThy1PSEN1M146VAPPSwe10Arte
• astrocytosis_Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte
  http://metadb.riken.jp/0003354IC57BL6CBATgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10Arte
• abnormal response to novel object_Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte
  http://metadb.riken.jp/0003461IC57BL6CBATgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10Arte
• cerebral amyloid angiopathy_Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/0
  http://metadb.riken.jp/0004254IC57BL6CBATgThy1PSEN1M146VAPPSwe10Arte0TgThy1PSEN1M146VAPPSwe10Arte
• cerebral amyloid angiopathy_Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte
  http://metadb.riken.jp/0004254IC57BL6CBATgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10Arte
• abnormal neurite morphology_Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/0
  http://metadb.riken.jp/0008415IC57BL6CBATgThy1PSEN1M146VAPPSwe10Arte0TgThy1PSEN1M146VAPPSwe10Arte
• abnormal neurite morphology_Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte
  http://metadb.riken.jp/0008415IC57BL6CBATgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10Arte
• abnormal spatial working memory_Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte
  http://metadb.riken.jp/0008428IC57BL6CBATgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10Arte
• decreased survivor rate_Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte
  http://metadb.riken.jp/0008770IC57BL6CBATgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10Arte
• microgliosis_Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte/Tg(Thy1-PSEN1*M146V,-APP*Swe)10Arte
  http://metadb.riken.jp/0008918IC57BL6CBATgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10ArteTgThy1PSEN1M146VAPPSwe10Arte