Fangfang. Yin, et.al., Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice., The Journal of experimental medicine, 2010, 207

http://rdf.ncbi.nlm.nih.gov/pubmed/20026663

Fangfang. Yin, et.al., Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice., The Journal of experimental medicine, 2010, 207

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Grn<tm1.1Aidi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4421705
• Grn<tm1Aidi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4421704

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• astrocytosis_Grn<tm1.1Aidi>/Grn<tm1.1Aidi>
  http://metadb.riken.jp/0003354IC57BL6C57BL6JGrntm11AidiGrntm11AidiGrntm11Aidi
• abnormal microglial cell physiology_Grn<tm1.1Aidi>/Grn<tm1.1Aidi>
  http://metadb.riken.jp/0003691IC57BL6C57BL6JGrntm11AidiGrntm11AidiGrntm11Aidi
• microgliosis_Grn<tm1.1Aidi>/Grn<tm1.1Aidi>
  http://metadb.riken.jp/0008918IC57BL6C57BL6JGrntm11AidiGrntm11AidiGrntm11Aidi
• increased susceptibility to bacterial infection_Grn<tm1.1Aidi>/Grn<tm1.1Aidi>
  http://metadb.riken.jp/0002412IC57BL6C57BL6JGrntm11AidiGrntm11AidiGrntm11Aidi
• increased interleukin-12 secretion_Grn<tm1.1Aidi>/Grn<tm1.1Aidi>
  http://metadb.riken.jp/0008663IC57BL6C57BL6JGrntm11AidiGrntm11AidiGrntm11Aidi
• increased susceptibility to injury_Grn<tm1.1Aidi>/Grn<tm1.1Aidi>
  http://metadb.riken.jp/0005165IC57BL6C57BL6JGrntm11AidiGrntm11AidiGrntm11Aidi
• increased interleukin-6 secretion_Grn<tm1.1Aidi>/Grn<tm1.1Aidi>
  http://metadb.riken.jp/0008705IC57BL6C57BL6JGrntm11AidiGrntm11AidiGrntm11Aidi
• increased tumor necrosis factor secretion_Grn<tm1.1Aidi>/Grn<tm1.1Aidi>
  http://metadb.riken.jp/0008560IC57BL6C57BL6JGrntm11AidiGrntm11AidiGrntm11Aidi
• abnormal macrophage physiology_Grn<tm1.1Aidi>/Grn<tm1.1Aidi>
  http://metadb.riken.jp/0002451IC57BL6C57BL6JGrntm11AidiGrntm11AidiGrntm11Aidi
• abnormal chemokine secretion_Grn<tm1.1Aidi>/Grn<tm1.1Aidi>
  http://metadb.riken.jp/0008722IC57BL6C57BL6JGrntm11AidiGrntm11AidiGrntm11Aidi

class

http://purl.org/net/cito/citesAsAuthority

• Grn<tm1.1Aidi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4421705
• Grn<tm1Aidi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4421704