Victoria E. DeMambro, et.al., A novel spontaneous mutation of Irs1 in mice results in hyperinsulinemia, reduced growth, low bone mass and impaired adipogenesis., The Journal of endocrinology, 2010, 204

http://rdf.ncbi.nlm.nih.gov/pubmed/20032200

Victoria E. DeMambro, et.al., A novel spontaneous mutation of Irs1 in mice results in hyperinsulinemia, reduced growth, low bone mass and impaired adipogenesis., The Journal of endocrinology, 2010, 204

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Irs1<Sml>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3639880

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased bone mineral density_Irs1<Sml>/Irs1<+>
  http://metadb.riken.jp/0000063C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1Irs1SmlIrs1
• decreased bone mineral density_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0000063C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• abnormal femur morphology_Irs1<Sml>/Irs1<+>
  http://metadb.riken.jp/0000559C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1Irs1SmlIrs1
• abnormal femur morphology_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0000559C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• thin tail_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0000589C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• short tail_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0000592C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
他23件を見る
• decreased body weight_Irs1<Sml>/Irs1<+>
  http://metadb.riken.jp/0001262C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1Irs1SmlIrs1
• decreased body weight_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0001262C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• decreased body size_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0001265C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• increased circulating insulin level_Irs1<Sml>/Irs1<+>
  http://metadb.riken.jp/0002079C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1Irs1SmlIrs1
• increased circulating insulin level_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0002079C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• abnormal tail morphology_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0002111C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• abnormal bone mineralization_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0002896C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• short femur_Irs1<Sml>/Irs1<+>
  http://metadb.riken.jp/0003109C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1Irs1SmlIrs1
• short femur_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0003109C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• abnormal bone structure_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0003795C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• increased osteoclast cell number_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0004984C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• increased osteoblast cell number_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0004988C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• abnormal osteoblast physiology_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0005006C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• impaired glucose tolerance_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0005293C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• insulin resistance_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0005331C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• decreased percent body fat/body weight_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0005459C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• decreased circulating glucose level_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0005560C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• decreased long bone epiphyseal plate size_Irs1<Sml>/Irs1<+>
  http://metadb.riken.jp/0006396C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1Irs1SmlIrs1
• decreased long bone epiphyseal plate size_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0006396C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• proportional dwarf_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0008974C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• decreased trabecular bone thickness_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0009346C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml
• decreased total body fat amount_Irs1<Sml>/Irs1<+>
  http://metadb.riken.jp/0010025C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1Irs1SmlIrs1
• increased or absent threshold for auditory brainstem response_Irs1<Sml>/Irs1<Sml>
  http://metadb.riken.jp/0011967C3CgIrs1SmlH2bGrsrJIrs1SmlIrs1SmlIrs1Sml

class

http://purl.org/net/cito/citesAsAuthority

• Irs1<Sml>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3639880