Lin. Deng, et.al., A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesis., The American journal of pathology, 2010, 176

http://rdf.ncbi.nlm.nih.gov/pubmed/20042677

Lin. Deng, et.al., A novel mouse model of inflammatory bowel disease links mammalian target of rapamycin-dependent hyperproliferation of colonic epithelium to inflammation-associated tumorigenesis., The American journal of pathology, 2010, 176

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Csf1r-icre)1Jwp
  http://metadb.riken.jp/db/mgi_rdf/MGI:4429470

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Csf1r-icre)1Jwp
  http://metadb.riken.jp/db/mgi_rdf/MGI:4429470

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal acute inflammation_Stat3<tm1Dlv>/Stat3<tm1Dlv>,Tg(Csf1r-icre)1Jwp/0
  http://metadb.riken.jp/0002498I129P2OlaHsdC57BL6FVBStat3tm1DlvStat3tm1DlvTgCsf1ricre1Jwp0TgCsf1ricre1JwpStat3tm1Dlv
• increased granulocyte number_Stat3<tm1Dlv>/Stat3<tm1Dlv>,Tg(Csf1r-icre)1Jwp/0
  http://metadb.riken.jp/0000322I129P2OlaHsdC57BL6FVBStat3tm1DlvStat3tm1DlvTgCsf1ricre1Jwp0TgCsf1ricre1JwpStat3tm1Dlv
• abnormal cecum morphology_Stat3<tm1Dlv>/Stat3<tm1Dlv>,Tg(Csf1r-icre)1Jwp/0
  http://metadb.riken.jp/0000494I129P2OlaHsdC57BL6FVBStat3tm1DlvStat3tm1DlvTgCsf1ricre1Jwp0TgCsf1ricre1JwpStat3tm1Dlv
• increased carcinoma incidence_Stat3<tm1Dlv>/Stat3<tm1Dlv>,Tg(Csf1r-icre)1Jwp/0
  http://metadb.riken.jp/0002038I129P2OlaHsdC57BL6FVBStat3tm1DlvStat3tm1DlvTgCsf1ricre1Jwp0TgCsf1ricre1JwpStat3tm1Dlv
• abnormal intestinal mucosa morphology_Stat3<tm1Dlv>/Stat3<tm1Dlv>,Tg(Csf1r-icre)1Jwp/0
  http://metadb.riken.jp/0000511I129P2OlaHsdC57BL6FVBStat3tm1DlvStat3tm1DlvTgCsf1ricre1Jwp0TgCsf1ricre1JwpStat3tm1Dlv
• colitis_Stat3<tm1Dlv>/Stat3<tm1Dlv>,Tg(Csf1r-icre)1Jwp/0
  http://metadb.riken.jp/0002816I129P2OlaHsdC57BL6FVBStat3tm1DlvStat3tm1DlvTgCsf1ricre1Jwp0TgCsf1ricre1JwpStat3tm1Dlv
• abnormal inflammatory response_Stat3<tm1Dlv>/Stat3<tm1Dlv>,Tg(Csf1r-icre)1Jwp/0
  http://metadb.riken.jp/0001845I129P2OlaHsdC57BL6FVBStat3tm1DlvStat3tm1DlvTgCsf1ricre1Jwp0TgCsf1ricre1JwpStat3tm1Dlv
• hypoactivity_Stat3<tm1Dlv>/Stat3<tm1Dlv>,Tg(Csf1r-icre)1Jwp/0
  http://metadb.riken.jp/0001402I129P2OlaHsdC57BL6FVBStat3tm1DlvStat3tm1DlvTgCsf1ricre1Jwp0TgCsf1ricre1JwpStat3tm1Dlv
• abnormal colon morphology_Stat3<tm1Dlv>/Stat3<tm1Dlv>,Tg(Csf1r-icre)1Jwp/0
  http://metadb.riken.jp/0000495I129P2OlaHsdC57BL6FVBStat3tm1DlvStat3tm1DlvTgCsf1ricre1Jwp0TgCsf1ricre1JwpStat3tm1Dlv
• increased macrophage cell number_Stat3<tm1Dlv>/Stat3<tm1Dlv>,Tg(Csf1r-icre)1Jwp/0
  http://metadb.riken.jp/0005425I129P2OlaHsdC57BL6FVBStat3tm1DlvStat3tm1DlvTgCsf1ricre1Jwp0TgCsf1ricre1JwpStat3tm1Dlv
• increased T cell number_Stat3<tm1Dlv>/Stat3<tm1Dlv>,Tg(Csf1r-icre)1Jwp/0
  http://metadb.riken.jp/0005015I129P2OlaHsdC57BL6FVBStat3tm1DlvStat3tm1DlvTgCsf1ricre1Jwp0TgCsf1ricre1JwpStat3tm1Dlv
• diarrhea_Stat3<tm1Dlv>/Stat3<tm1Dlv>,Tg(Csf1r-icre)1Jwp/0
  http://metadb.riken.jp/0005036I129P2OlaHsdC57BL6FVBStat3tm1DlvStat3tm1DlvTgCsf1ricre1Jwp0TgCsf1ricre1JwpStat3tm1Dlv
• colon polyps_Stat3<tm1Dlv>/Stat3<tm1Dlv>,Tg(Csf1r-icre)1Jwp/0
  http://metadb.riken.jp/0003269I129P2OlaHsdC57BL6FVBStat3tm1DlvStat3tm1DlvTgCsf1ricre1Jwp0TgCsf1ricre1JwpStat3tm1Dlv
• weight loss_Stat3<tm1Dlv>/Stat3<tm1Dlv>,Tg(Csf1r-icre)1Jwp/0
  http://metadb.riken.jp/0001263I129P2OlaHsdC57BL6FVBStat3tm1DlvStat3tm1DlvTgCsf1ricre1Jwp0TgCsf1ricre1JwpStat3tm1Dlv
• increased gastrointestinal tumor incidence_Stat3<tm1Dlv>/Stat3<tm1Dlv>,Tg(Csf1r-icre)1Jwp/0
  http://metadb.riken.jp/0010279I129P2OlaHsdC57BL6FVBStat3tm1DlvStat3tm1DlvTgCsf1ricre1Jwp0TgCsf1ricre1JwpStat3tm1Dlv
• decreased body weight_Stat3<tm1Dlv>/Stat3<tm1Dlv>,Tg(Csf1r-icre)1Jwp/0
  http://metadb.riken.jp/0001262I129P2OlaHsdC57BL6FVBStat3tm1DlvStat3tm1DlvTgCsf1ricre1Jwp0TgCsf1ricre1JwpStat3tm1Dlv