Hong Hua. Li, et.al., Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice., EMBO molecular medicine, 2009, 1

http://rdf.ncbi.nlm.nih.gov/pubmed/20049703

Hong Hua. Li, et.al., Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice., EMBO molecular medicine, 2009, 1

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317121
• Del(5Gtf2i-Limk1)1Uta
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317120
• Limk1<tm2Uta>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317125
• Gtf2i<tm1Uta>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317124
• Trim50<tm1Uta>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317123
• Limk1<tm1Uta>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317122

class

http://purl.org/net/cito/citesAsAuthority

• Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317121
• Del(5Gtf2i-Limk1)1Uta
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317120
• Limk1<tm2Uta>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317125
• Gtf2i<tm1Uta>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317124
• Trim50<tm1Uta>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317123
• Limk1<tm1Uta>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5317122

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• postnatal growth retardation_Del(5Limk1-Trim50)2Uta/+
  http://metadb.riken.jp/0001732I129S7SvEvBrdC57BL6JDel5Limk1Trim502UtaDel5Limk1Trim502Uta
• herniated abdominal wall_Del(5Limk1-Trim50)2Uta/+
  http://metadb.riken.jp/0000757I129S7SvEvBrdC57BL6JDel5Limk1Trim502UtaDel5Limk1Trim502Uta
• small lateral ventricles_Del(5Gtf2i-Limk1)1Uta/+
  http://metadb.riken.jp/0013908I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Gtf2iLimk11Uta
• postnatal growth retardation_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0001732I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta
• abnormal social investigation_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0001360I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta
• abnormal facial morphology_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0003743I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta
• decreased exploration in new environment_Del(5Limk1-Trim50)2Uta/+
  http://metadb.riken.jp/0001417I129S7SvEvBrdC57BL6JDel5Limk1Trim502UtaDel5Limk1Trim502Uta
• abnormal vagina morphology_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0001139I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta
• abnormal startle reflex_Del(5Limk1-Trim50)2Uta/+
  http://metadb.riken.jp/0001486I129S7SvEvBrdC57BL6JDel5Limk1Trim502UtaDel5Limk1Trim502Uta
• herniated abdominal wall_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0000757I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta
• decreased brain weight_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0002175I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta
• abnormal vagina morphology_Del(5Limk1-Trim50)2Uta/+
  http://metadb.riken.jp/0001139I129S7SvEvBrdC57BL6JDel5Limk1Trim502UtaDel5Limk1Trim502Uta
• decreased body weight_Del(5Limk1-Trim50)2Uta/+
  http://metadb.riken.jp/0001262I129S7SvEvBrdC57BL6JDel5Limk1Trim502UtaDel5Limk1Trim502Uta
• decreased cranium width_Del(5Limk1-Trim50)2Uta/+
  http://metadb.riken.jp/0008526I129S7SvEvBrdC57BL6JDel5Limk1Trim502UtaDel5Limk1Trim502Uta
• postnatal growth retardation_Del(5Gtf2i-Limk1)1Uta/+
  http://metadb.riken.jp/0001732I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Gtf2iLimk11Uta
• increased startle reflex_Del(5Gtf2i-Limk1)1Uta/+
  http://metadb.riken.jp/0001488I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Gtf2iLimk11Uta
• decreased prepulse inhibition_Del(5Gtf2i-Limk1)1Uta/+
  http://metadb.riken.jp/0009142I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Gtf2iLimk11Uta
• decreased exploration in new environment_Del(5Gtf2i-Limk1)1Uta/+
  http://metadb.riken.jp/0001417I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Gtf2iLimk11Uta
• impaired coordination_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0001405I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta
• decreased exploration in new environment_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0001417I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta
• increased cranium length_Del(5Gtf2i-Limk1)1Uta/+
  http://metadb.riken.jp/0011812I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Gtf2iLimk11Uta
• decreased thermal nociceptive threshold_Del(5Gtf2i-Limk1)1Uta/+
  http://metadb.riken.jp/0003998I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Gtf2iLimk11Uta
• decreased brain size_Del(5Limk1-Trim50)2Uta/+
  http://metadb.riken.jp/0000774I129S7SvEvBrdC57BL6JDel5Limk1Trim502UtaDel5Limk1Trim502Uta
• abnormal social investigation_Del(5Limk1-Trim50)2Uta/+
  http://metadb.riken.jp/0001360I129S7SvEvBrdC57BL6JDel5Limk1Trim502UtaDel5Limk1Trim502Uta
• abnormal facial morphology_Del(5Limk1-Trim50)2Uta/+
  http://metadb.riken.jp/0003743I129S7SvEvBrdC57BL6JDel5Limk1Trim502UtaDel5Limk1Trim502Uta
• abnormal blood vessel physiology_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0000249I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta
• premature death_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0002083I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta
• decreased brain weight_Del(5Limk1-Trim50)2Uta/+
  http://metadb.riken.jp/0002175I129S7SvEvBrdC57BL6JDel5Limk1Trim502UtaDel5Limk1Trim502Uta
• increased thigmotaxis_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0002797I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta
• abnormal cranium size_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0010031I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta
• premature death_Del(5Limk1-Trim50)2Uta/+
  http://metadb.riken.jp/0002083I129S7SvEvBrdC57BL6JDel5Limk1Trim502UtaDel5Limk1Trim502Uta
• decreased aggression towards mice_Del(5Gtf2i-Limk1)1Uta/+
  http://metadb.riken.jp/0003863I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Gtf2iLimk11Uta
• decreased aggression towards mice_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0003863I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta
• increased neuron number_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0008947I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta
• abnormal blood vessel physiology_Del(5Limk1-Trim50)2Uta/+
  http://metadb.riken.jp/0000249I129S7SvEvBrdC57BL6JDel5Limk1Trim502UtaDel5Limk1Trim502Uta
• abnormal cranium size_Del(5Limk1-Trim50)2Uta/+
  http://metadb.riken.jp/0010031I129S7SvEvBrdC57BL6JDel5Limk1Trim502UtaDel5Limk1Trim502Uta
• decreased brain size_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0000774I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta
• impaired cued conditioning behavior_Del(5Limk1-Trim50)2Uta/+
  http://metadb.riken.jp/0009456I129S7SvEvBrdC57BL6JDel5Limk1Trim502UtaDel5Limk1Trim502Uta
• rectal prolapse_Del(5Limk1-Trim50)2Uta/+
  http://metadb.riken.jp/0000493I129S7SvEvBrdC57BL6JDel5Limk1Trim502UtaDel5Limk1Trim502Uta
• decreased body weight_Del(5Gtf2i-Limk1)1Uta/+
  http://metadb.riken.jp/0001262I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Gtf2iLimk11Uta
• impaired contextual conditioning behavior_Del(5Limk1-Trim50)2Uta/+
  http://metadb.riken.jp/0009454I129S7SvEvBrdC57BL6JDel5Limk1Trim502UtaDel5Limk1Trim502Uta
• small lateral ventricles_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0013908I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta
• lethality, incomplete penetrance_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0010831I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta
• impaired coordination_Del(5Gtf2i-Limk1)1Uta/+
  http://metadb.riken.jp/0001405I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Gtf2iLimk11Uta
• increased neuron number_Del(5Gtf2i-Limk1)1Uta/+
  http://metadb.riken.jp/0008947I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Gtf2iLimk11Uta
• rectal prolapse_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0000493I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta
• abnormal social investigation_Del(5Gtf2i-Limk1)1Uta/+
  http://metadb.riken.jp/0001360I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Gtf2iLimk11Uta
• decreased cranium width_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0008526I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta
• decreased brain size_Del(5Gtf2i-Limk1)1Uta/+
  http://metadb.riken.jp/0000774I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Gtf2iLimk11Uta
• decreased body weight_Del(5Gtf2i-Limk1)1Uta/Del(5Limk1-Trim50)2Uta
  http://metadb.riken.jp/0001262I129S7SvEvBrdC57BL6JDel5Gtf2iLimk11UtaDel5Limk1Trim502UtaDel5Gtf2iLimk11UtaDel5Limk1Trim502Uta