Almira. Kurbegovic, et.al., Pkd1 transgenic mice: adult model of polycystic kidney disease with extrarenal and renal phenotypes., Human molecular genetics, 2010, 19

http://rdf.ncbi.nlm.nih.gov/pubmed/20053665

Almira. Kurbegovic, et.al., Pkd1 transgenic mice: adult model of polycystic kidney disease with extrarenal and renal phenotypes., Human molecular genetics, 2010, 19

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Pkd1)18Mtru
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437719
• Tg(Pkd1)26Mtru
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437718
• Tg(Pkd1)6Mtru
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437717

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• small cerebellum_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0000852IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• kidney cortex cysts_Tg(Pkd1)18Mtru/0
  http://metadb.riken.jp/0000522IC57BL6JCBAJTgPkd118Mtru0TgPkd118Mtru
• calcified aortic valve_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0006116IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• premature death_Tg(Pkd1)18Mtru/0
  http://metadb.riken.jp/0002083IC57BL6JCBAJTgPkd118Mtru0TgPkd118Mtru
• cardiac fibrosis_Tg(Pkd1)18Mtru/0
  http://metadb.riken.jp/0003141IC57BL6JCBAJTgPkd118Mtru0TgPkd118Mtru
• kidney medulla cysts_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0011307IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• dilated heart_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0004937IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• nephrocalcinosis_Tg(Pkd1)18Mtru/0
  http://metadb.riken.jp/0003197IC57BL6JCBAJTgPkd118Mtru0TgPkd118Mtru
• abnormal myocardium layer morphology_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0005329IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• increased circulating phosphate level_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0001566IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• liver cysts_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0003327IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• aneurysm_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0003279IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• renal cast_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0011402IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• abnormal aortic valve cusp morphology_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0010595IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• decreased urine protein level_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0002963IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• kidney cortex cysts_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0000522IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• glomerulosclerosis_Tg(Pkd1)18Mtru/0
  http://metadb.riken.jp/0005264IC57BL6JCBAJTgPkd118Mtru0TgPkd118Mtru
• thick ventricular wall_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0002953IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• abnormal renal tubule epithelium morphology_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0009640IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• decreased urine urea nitrogen level_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0011467IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• increased cardiac muscle contractility_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0005599IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• pale kidney_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0004969IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• intracranial hemorrhage_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0001915IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• premature death_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0002083IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• glomerulosclerosis_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0005264IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• pale kidney_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0004969IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• increased cardiac output_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0003394IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• increased cardiac stroke volume_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0011951IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• liver fibrosis_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0003333IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• renal cast_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0011402IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• abnormal cerebellum development_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0000854IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• increased hepatocyte proliferation_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0003893IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• renal interstitial fibrosis_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0003215IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• increased circulating sodium level_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0005633IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• kidney medulla cysts_Tg(Pkd1)18Mtru/0
  http://metadb.riken.jp/0011307IC57BL6JCBAJTgPkd118Mtru0TgPkd118Mtru
• decreased urine creatinine level_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0011471IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• dilated renal tubules_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0002705IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• increased blood osmolality_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0008997IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• nephrocalcinosis_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0003197IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• increased urine protein level_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0002962IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• thick interventricular septum_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0010724IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• kidney cortex cysts_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0000522IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• hematuria_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0005161IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• kidney cysts_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0003675IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• dystrophic cardiac calcinosis_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0002837IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• polyuria_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0001762IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• abnormal renal tubule epithelium morphology_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0009640IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• kidney epithelium hyperplasia_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0004968IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• abnormal aortic valve cusp morphology_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0010595IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• heart left ventricle hypertrophy_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0002625IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• cardiac hypertrophy_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0001625IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• dilated heart_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0004937IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• decreased hematocrit_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0000208IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• dilated brain ventricles_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0012676IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• hematuria_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0005161IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• increased heart weight_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0002833IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• decreased hematocrit_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0000208IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• increased urine osmolality_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0008055IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• decreased hematocrit_Tg(Pkd1)18Mtru/0
  http://metadb.riken.jp/0000208IC57BL6JCBAJTgPkd118Mtru0TgPkd118Mtru
• thick ventricular wall_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0002953IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• heart left ventricle hypertrophy_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0002625IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• thick interventricular septum_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0010724IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• kidney cysts_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0003675IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• glomerulosclerosis_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0005264IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• renal interstitial fibrosis_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0003215IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• liver fibrosis_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0003333IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• hypertension_Tg(Pkd1)18Mtru/0
  http://metadb.riken.jp/0000231IC57BL6JCBAJTgPkd118Mtru0TgPkd118Mtru
• nephrocalcinosis_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0003197IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• increased hepatocyte proliferation_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0003893IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• polyuria_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0001762IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• cardiac hypertrophy_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0001625IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• hypertension_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0000231IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• increased circulating sodium level_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0005633IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• dilated renal tubules_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0002705IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• aortic valve stenosis_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0006117IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• pale kidney_Tg(Pkd1)18Mtru/0
  http://metadb.riken.jp/0004969IC57BL6JCBAJTgPkd118Mtru0TgPkd118Mtru
• nephrolithiasis_Tg(Pkd1)18Mtru/0
  http://metadb.riken.jp/0002708IC57BL6JCBAJTgPkd118Mtru0TgPkd118Mtru
• nephrolithiasis_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0002708IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• increased urine protein level_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0002962IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• premature death_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0002083IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• nephrolithiasis_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0002708IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• increased blood osmolality_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0008997IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• liver cysts_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0003327IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• increased kidney cell proliferation_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0011440IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• hydroencephaly_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0001891IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• kidney epithelium hyperplasia_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0004968IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• kidney cysts_Tg(Pkd1)18Mtru/0
  http://metadb.riken.jp/0003675IC57BL6JCBAJTgPkd118Mtru0TgPkd118Mtru
• increased urine protein level_Tg(Pkd1)18Mtru/0
  http://metadb.riken.jp/0002962IC57BL6JCBAJTgPkd118Mtru0TgPkd118Mtru
• increased kidney cell proliferation_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0011440IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• abnormal sagittal suture morphology_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0003843IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• kidney medulla cysts_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0011307IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru
• cardiac fibrosis_Tg(Pkd1)26Mtru/0
  http://metadb.riken.jp/0003141IC57BL6JCBAJTgPkd126Mtru0TgPkd126Mtru
• increased heart weight_Tg(Pkd1)6Mtru/0
  http://metadb.riken.jp/0002833IC57BL6JCBAJTgPkd16Mtru0TgPkd16Mtru

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Pkd1)18Mtru
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437719
• Tg(Pkd1)26Mtru
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437718
• Tg(Pkd1)6Mtru
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437717