Sheng. Wu, et.al., Disruption of the single copy gonadotropin-releasing hormone receptor in mice by gene trap: severe reduction of reproductive organs and functions in developing and adult mice., Endocrinology, 2010, 151

http://rdf.ncbi.nlm.nih.gov/pubmed/20068010

Sheng. Wu, et.al., Disruption of the single copy gonadotropin-releasing hormone receptor in mice by gene trap: severe reduction of reproductive organs and functions in developing and adult mice., Endocrinology, 2010, 151

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal external male genitalia morphology_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0009199I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• constricted vagina orifice_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0001143I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• delayed vaginal opening_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0002636I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• small penis_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0005188I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• decreased circulating progesterone level_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0005185I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• decreased circulating testosterone level_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0002780I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• decreased circulating follicle stimulating hormone level_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0002790I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• female infertility_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0001926I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• abnormal female reproductive system physiology_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0003699I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• thin uterus_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0009081I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• abnormal testis morphology_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0001146I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• small epididymis_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0004930I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• small seminal vesicle_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0001157I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• decreased testis weight_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0004852I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• impaired ovarian folliculogenesis_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0001129I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• abnormal seminiferous tubule morphology_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0002216I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• small male preputial glands_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0002716I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• abnormal spermatocyte morphology_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0006379I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• decreased ovary weight_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0004856I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• decreased circulating luteinizing hormone level_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0002773I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• abnormal internal female genitalia morphology_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0009209I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• abnormal internal male genitalia morphology_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0009205I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• absent estrous cycle_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0009009I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• small testis_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0001147I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• small seminiferous tubules_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0001153I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• increased body weight_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0001260I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• abnormal ovary morphology_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0001126I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• male infertility_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0001925I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd
• decreased circulating estradiol level_Gnrhr<Gt(181A6)Cmhd>/Gnrhr<Gt(181A6)Cmhd>
  http://metadb.riken.jp/0005181I129S1Sv129X1SvJC57BL6JGnrhrGt181A6CmhdGnrhrGt181A6CmhdGnrhrGt181A6Cmhd

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD22844
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD22844