Hai. Song, et.al., Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

http://rdf.ncbi.nlm.nih.gov/pubmed/20080598

Hai. Song, et.al., Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Stk3<tm1.1Yy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4422170
• Stk4<tm1.1Yy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4422173
• Stk4<tm1Yy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4422171
• Stk3<tm1Yy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4422169

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal liver morphology_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000598IC57BL6CBADBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyTgAlbcre21Mgn0Stk4tm11YyStk3tm11YyTgAlbcre21MgnStk3tm1Yy
• decreased fibroblast apoptosis_Stk3<tm1.1Yy>/Stk3<tm1.1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0013502IC57BL6CBAStk3tm11YyStk3tm11YyStk4tm11YyStk4tm11YyStk4tm11YyStk3tm11Yy
• enlarged liver_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0000599IC57BL6CBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyTgCAGcreEsr15Amc0TgCAGcreEsr15AmcStk3tm1YyStk3tm11YyStk4tm11Yy
• decreased hepatocyte apoptosis_Stk3<tm1.1Yy>/Stk3<tm1.1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0008891IC57BL6CBAStk3tm11YyStk3tm11YyStk4tm11YyStk4tm11YyStk4tm11YyStk3tm11Yy
• abnormal embryo development_Stk3<tm1.1Yy>/Stk3<tm1.1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0001672IC57BL6CBAStk3tm11YyStk3tm11YyStk4tm11YyStk4tm11YyStk4tm11YyStk3tm11Yy
• embryonic lethality during organogenesis, complete penetrance_Stk3<tm1.1Yy>/Stk3<tm1.1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0011098IC57BL6CBAStk3tm11YyStk3tm11YyStk4tm11YyStk4tm11YyStk4tm11YyStk3tm11Yy
• abnormal response/metabolism to endogenous compounds_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0003638IC57BL6CBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyStk3tm1YyStk3tm11YyStk4tm11Yy
• abnormal limb bone morphology_Stk3<tm1Yy>/Stk3<tm1.1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>,Tg(Prrx1-cre)1Cjt/0
  http://metadb.riken.jp/0002115IC57BL6CBASJLStk3tm1YyStk3tm11YyStk4tm11YyStk4tm11YyTgPrrx1cre1Cjt0Stk3tm1YyStk3tm11YyTgPrrx1cre1CjtStk4tm11Yy
• increased hepatocyte proliferation_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0003893IC57BL6CBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyTgCAGcreEsr15Amc0TgCAGcreEsr15AmcStk3tm1YyStk3tm11YyStk4tm11Yy
• decreased length of long bones_Stk3<tm1Yy>/Stk3<tm1.1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>,Tg(Prrx1-cre)1Cjt/0
  http://metadb.riken.jp/0004686IC57BL6CBASJLStk3tm1YyStk3tm11YyStk4tm11YyStk4tm11YyTgPrrx1cre1Cjt0Stk3tm1YyStk3tm11YyTgPrrx1cre1CjtStk4tm11Yy
• increased hepatocyte proliferation_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003893IC57BL6CBADBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyTgAlbcre21Mgn0Stk4tm11YyStk3tm11YyTgAlbcre21MgnStk3tm1Yy
• decreased circulating alanine transaminase level_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0002942IC57BL6CBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyStk3tm1YyStk3tm11YyStk4tm11Yy
• enlarged spleen_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0000691IC57BL6CBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyTgCAGcreEsr15Amc0TgCAGcreEsr15AmcStk3tm1YyStk3tm11YyStk4tm11Yy
• decreased hepatocyte apoptosis_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0008891IC57BL6CBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyStk3tm1YyStk3tm11YyStk4tm11Yy
• abnormal cartilage morphology_Stk3<tm1Yy>/Stk3<tm1.1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>,Tg(Prrx1-cre)1Cjt/0
  http://metadb.riken.jp/0000163IC57BL6CBASJLStk3tm1YyStk3tm11YyStk4tm11YyStk4tm11YyTgPrrx1cre1Cjt0Stk3tm1YyStk3tm11YyTgPrrx1cre1CjtStk4tm11Yy
• increased carcinoma incidence_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0002038IC57BL6CBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyTgCAGcreEsr15Amc0TgCAGcreEsr15AmcStk3tm1YyStk3tm11YyStk4tm11Yy
• abnormal liver physiology_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0000609IC57BL6CBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyStk3tm1YyStk3tm11YyStk4tm11Yy
• decreased sensitivity to induced morbidity/mortality_Stk3<tm1.1Yy>/Stk3<+>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0009764IC57BL6CBAStk3tm11YyStk3Stk4tm11YyStk4tm11YyStk3Stk3tm11YyStk4tm11Yy
• abnormal liver physiology_Stk3<tm1.1Yy>/Stk3<+>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0000609IC57BL6CBAStk3tm11YyStk3Stk4tm11YyStk4tm11YyStk3Stk3tm11YyStk4tm11Yy
• increased hepatocellular carcinoma incidence_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0003331IC57BL6CBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyTgCAGcreEsr15Amc0TgCAGcreEsr15AmcStk3tm1YyStk3tm11YyStk4tm11Yy
• abnormal skeleton physiology_Stk3<tm1Yy>/Stk3<tm1.1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>,Tg(Prrx1-cre)1Cjt/0
  http://metadb.riken.jp/0001533IC57BL6CBASJLStk3tm1YyStk3tm11YyStk4tm11YyStk4tm11YyTgPrrx1cre1Cjt0Stk3tm1YyStk3tm11YyTgPrrx1cre1CjtStk4tm11Yy
• increased hepatocyte apoptosis_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003887IC57BL6CBADBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyTgAlbcre21Mgn0Stk4tm11YyStk3tm11YyTgAlbcre21MgnStk3tm1Yy
• increased circulating alanine transaminase level_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0002941IC57BL6CBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyStk4tm11YyStk3tm1YyStk3tm11Yy
• abnormal hepatocyte morphology_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000607IC57BL6CBADBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyTgAlbcre21Mgn0Stk4tm11YyStk3tm11YyTgAlbcre21MgnStk3tm1Yy
• no abnormal phenotype detected_Stk3<tm1.1Yy>/Stk3<tm1.1Yy>
  http://metadb.riken.jp/0002169IC57BL6CBAStk3tm11YyStk3tm11YyStk3tm11Yy
• decreased sensitivity to induced morbidity/mortality_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0009764IC57BL6CBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyStk3tm1YyStk3tm11YyStk4tm11Yy
• decreased circulating aspartate transaminase level_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0005632IC57BL6CBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyStk3tm1YyStk3tm11YyStk4tm11Yy
• no abnormal phenotype detected_Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0002169IC57BL6CBAStk4tm11YyStk4tm11YyStk4tm11Yy
• enlarged liver_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000599IC57BL6CBADBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyTgAlbcre21Mgn0Stk4tm11YyStk3tm11YyTgAlbcre21MgnStk3tm1Yy
• decreased circulating aspartate transaminase level_Stk3<tm1.1Yy>/Stk3<+>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0005632IC57BL6CBAStk3tm11YyStk3Stk4tm11YyStk4tm11YyStk3Stk3tm11YyStk4tm11Yy
• enlarged stomach_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0003883IC57BL6CBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyTgCAGcreEsr15Amc0TgCAGcreEsr15AmcStk3tm1YyStk3tm11YyStk4tm11Yy
• decreased hepatocyte apoptosis_Stk3<tm1.1Yy>/Stk3<+>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0008891IC57BL6CBAStk3tm11YyStk3Stk4tm11YyStk4tm11YyStk3Stk3tm11YyStk4tm11Yy
• enlarged heart_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0000274IC57BL6CBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyTgCAGcreEsr15Amc0TgCAGcreEsr15AmcStk3tm1YyStk3tm11YyStk4tm11Yy
• decreased circulating alanine transaminase level_Stk3<tm1.1Yy>/Stk3<+>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0002942IC57BL6CBAStk3tm11YyStk3Stk4tm11YyStk4tm11YyStk3Stk3tm11YyStk4tm11Yy
• increased liver tumor incidence_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0008019IC57BL6CBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyTgCAGcreEsr15Amc0TgCAGcreEsr15AmcStk3tm1YyStk3tm11YyStk4tm11Yy
• abnormal response/metabolism to endogenous compounds_Stk3<tm1.1Yy>/Stk3<+>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0003638IC57BL6CBAStk3tm11YyStk3Stk4tm11YyStk4tm11YyStk3Stk3tm11YyStk4tm11Yy
• short limbs_Stk3<tm1Yy>/Stk3<tm1.1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>,Tg(Prrx1-cre)1Cjt/0
  http://metadb.riken.jp/0000547IC57BL6CBASJLStk3tm1YyStk3tm11YyStk4tm11YyStk4tm11YyTgPrrx1cre1Cjt0Stk3tm1YyStk3tm11YyTgPrrx1cre1CjtStk4tm11Yy
• increased liver tumor incidence_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0008019IC57BL6CBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyStk4tm11YyStk3tm1YyStk3tm11Yy
• increased circulating aspartate transaminase level_Stk3<tm1.1Yy>/Stk3<tm1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0005343IC57BL6CBAStk3tm11YyStk3tm1YyStk4tm11YyStk4tm11YyStk4tm11YyStk3tm1YyStk3tm11Yy
• embryonic growth retardation_Stk3<tm1.1Yy>/Stk3<tm1.1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>
  http://metadb.riken.jp/0003984IC57BL6CBAStk3tm11YyStk3tm11YyStk4tm11YyStk4tm11YyStk4tm11YyStk3tm11Yy
• abnormal long bone hypertrophic chondrocyte zone_Stk3<tm1Yy>/Stk3<tm1.1Yy>,Stk4<tm1.1Yy>/Stk4<tm1.1Yy>,Tg(Prrx1-cre)1Cjt/0
  http://metadb.riken.jp/0000165IC57BL6CBASJLStk3tm1YyStk3tm11YyStk4tm11YyStk4tm11YyTgPrrx1cre1Cjt0Stk3tm1YyStk3tm11YyTgPrrx1cre1CjtStk4tm11Yy

class

http://purl.org/net/cito/citesAsAuthority

• Stk3<tm1.1Yy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4422170
• Stk4<tm1.1Yy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4422173
• Stk4<tm1Yy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4422171
• Stk3<tm1Yy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4422169

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD18655
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD18655
• CD16769
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16769
• CD16401
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16401
• CD28967
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD28967
• CD16536
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16536