Yulong. Liang, et.al., BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice., PLoS genetics, 2010, 6

http://rdf.ncbi.nlm.nih.gov/pubmed/20107607

Yulong. Liang, et.al., BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice., PLoS genetics, 2010, 6

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mcph1<tm1.2Kali>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4429492
• Mcph1<tm1.1Kali>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4429491

class

http://purl.org/net/cito/citesAsAuthority

• Mcph1<tm1.2Kali>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4429492
• Mcph1<tm1.1Kali>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4429491

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased body weight_Mcph1<tm1.2Kali>/Mcph1<tm1.2Kali>
  http://metadb.riken.jp/0001262I129S7SvEvBrdC57BL6JMcph1tm12KaliMcph1tm12KaliMcph1tm12Kali
• abnormal male meiosis_Mcph1<tm1.2Kali>/Mcph1<tm1.2Kali>
  http://metadb.riken.jp/0005169I129S7SvEvBrdC57BL6JMcph1tm12KaliMcph1tm12KaliMcph1tm12Kali
• absent ovarian follicles_Mcph1<tm1.2Kali>/Mcph1<tm1.2Kali>
  http://metadb.riken.jp/0002777I129S7SvEvBrdC57BL6JMcph1tm12KaliMcph1tm12KaliMcph1tm12Kali
• perinatal lethality, incomplete penetrance_Mcph1<tm1.2Kali>/Mcph1<tm1.2Kali>
  http://metadb.riken.jp/0011090I129S7SvEvBrdC57BL6JMcph1tm12KaliMcph1tm12KaliMcph1tm12Kali
• arrest of male meiosis_Mcph1<tm1.2Kali>/Mcph1<tm1.2Kali>
  http://metadb.riken.jp/0008261I129S7SvEvBrdC57BL6JMcph1tm12KaliMcph1tm12KaliMcph1tm12Kali
• abnormal spermatid morphology_Mcph1<tm1.2Kali>/Mcph1<tm1.2Kali>
  http://metadb.riken.jp/0006380I129S7SvEvBrdC57BL6JMcph1tm12KaliMcph1tm12KaliMcph1tm12Kali
• abnormal male germ cell apoptosis_Mcph1<tm1.2Kali>/Mcph1<tm1.2Kali>
  http://metadb.riken.jp/0008280I129S7SvEvBrdC57BL6JMcph1tm12KaliMcph1tm12KaliMcph1tm12Kali
• decreased ovary weight_Mcph1<tm1.2Kali>/Mcph1<tm1.2Kali>
  http://metadb.riken.jp/0004856I129S7SvEvBrdC57BL6JMcph1tm12KaliMcph1tm12KaliMcph1tm12Kali
• female infertility_Mcph1<tm1.2Kali>/Mcph1<tm1.2Kali>
  http://metadb.riken.jp/0001926I129S7SvEvBrdC57BL6JMcph1tm12KaliMcph1tm12KaliMcph1tm12Kali
• small testis_Mcph1<tm1.2Kali>/Mcph1<tm1.2Kali>
  http://metadb.riken.jp/0001147I129S7SvEvBrdC57BL6JMcph1tm12KaliMcph1tm12KaliMcph1tm12Kali
• induced chromosome breakage_Mcph1<tm1.2Kali>/Mcph1<tm1.2Kali>
  http://metadb.riken.jp/0004030I129S7SvEvBrdC57BL6JMcph1tm12KaliMcph1tm12KaliMcph1tm12Kali
• decreased male germ cell number_Mcph1<tm1.2Kali>/Mcph1<tm1.2Kali>
  http://metadb.riken.jp/0004901I129S7SvEvBrdC57BL6JMcph1tm12KaliMcph1tm12KaliMcph1tm12Kali
• increased cellular sensitivity to gamma-irradiation_Mcph1<tm1.2Kali>/Mcph1<tm1.2Kali>
  http://metadb.riken.jp/0002007I129S7SvEvBrdC57BL6JMcph1tm12KaliMcph1tm12KaliMcph1tm12Kali
• abnormal seminiferous tubule morphology_Mcph1<tm1.2Kali>/Mcph1<tm1.2Kali>
  http://metadb.riken.jp/0002216I129S7SvEvBrdC57BL6JMcph1tm12KaliMcph1tm12KaliMcph1tm12Kali
• abnormal T cell physiology_Mcph1<tm1.2Kali>/Mcph1<tm1.2Kali>
  http://metadb.riken.jp/0002444I129S7SvEvBrdC57BL6JMcph1tm12KaliMcph1tm12KaliMcph1tm12Kali
• male infertility_Mcph1<tm1.2Kali>/Mcph1<tm1.2Kali>
  http://metadb.riken.jp/0001925I129S7SvEvBrdC57BL6JMcph1tm12KaliMcph1tm12KaliMcph1tm12Kali
• increased mortality induced by gamma-irradiation_Mcph1<tm1.2Kali>/Mcph1<tm1.2Kali>
  http://metadb.riken.jp/0001658I129S7SvEvBrdC57BL6JMcph1tm12KaliMcph1tm12KaliMcph1tm12Kali

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD24330
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD24330