Céline. Lamacchia, et.al., Enhanced Th1 and Th17 responses and arthritis severity in mice with a deficiency of myeloid cell-specific interleukin-1 receptor antagonist., Arthritis and rheumatism, 2010, 62

http://rdf.ncbi.nlm.nih.gov/pubmed/20112392

Céline. Lamacchia, et.al., Enhanced Th1 and Th17 responses and arthritis severity in mice with a deficiency of myeloid cell-specific interleukin-1 receptor antagonist., Arthritis and rheumatism, 2010, 62

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Il1rn<tm1.1Cga>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4819784

class

http://purl.org/net/cito/citesAsAuthority

• Il1rn<tm1.1Cga>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4819784

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal chemokine secretion_Il1rn<tm1.1Cga>/Il1rn<tm1.1Cga>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0008722D1CgIl1rntm11CgaLyz2tm1creIfoIl1rntm11CgaIl1rntm11CgaLyz2tm1creIfoLyz2Lyz2tm1creIfoLyz2Il1rntm11Cga
• increased interferon-gamma secretion_Il1rn<tm1.1Cga>/Il1rn<tm1.1Cga>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0008566D1CgIl1rntm11CgaLyz2tm1creIfoIl1rntm11CgaIl1rntm11CgaLyz2tm1creIfoLyz2Lyz2tm1creIfoLyz2Il1rntm11Cga
• increased interleukin-17 secretion_Il1rn<tm1.1Cga>/Il1rn<tm1.1Cga>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0008681D1CgIl1rntm11CgaLyz2tm1creIfoIl1rntm11CgaIl1rntm11CgaLyz2tm1creIfoLyz2Lyz2tm1creIfoLyz2Il1rntm11Cga
• increased T cell proliferation_Il1rn<tm1.1Cga>/Il1rn<tm1.1Cga>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0005348D1CgIl1rntm11CgaLyz2tm1creIfoIl1rntm11CgaIl1rntm11CgaLyz2tm1creIfoLyz2Lyz2tm1creIfoLyz2Il1rntm11Cga
• increased interleukin-6 secretion_Il1rn<tm1.1Cga>/Il1rn<tm1.1Cga>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0008705D1CgIl1rntm11CgaLyz2tm1creIfoIl1rntm11CgaIl1rntm11CgaLyz2tm1creIfoLyz2Lyz2tm1creIfoLyz2Il1rntm11Cga
• increased interleukin-1 beta secretion_Il1rn<tm1.1Cga>/Il1rn<tm1.1Cga>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0008657D1CgIl1rntm11CgaLyz2tm1creIfoIl1rntm11CgaIl1rntm11CgaLyz2tm1creIfoLyz2Lyz2tm1creIfoLyz2Il1rntm11Cga
• increased susceptibility to induced arthritis_Il1rn<tm1.1Cga>/Il1rn<tm1.1Cga>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0003724D1CgIl1rntm11CgaLyz2tm1creIfoIl1rntm11CgaIl1rntm11CgaLyz2tm1creIfoLyz2Lyz2tm1creIfoLyz2Il1rntm11Cga