Xianting. Li, et.al., Enhanced striatal dopamine transmission and motor performance with LRRK2 overexpression in mice is eliminated by familial Parkinson's disease mutation G2019S., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30

http://rdf.ncbi.nlm.nih.gov/pubmed/20130188

Xianting. Li, et.al., Enhanced striatal dopamine transmission and motor performance with LRRK2 overexpression in mice is eliminated by familial Parkinson's disease mutation G2019S., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• enhanced coordination_Tg(Lrrk2)6Yue/0
  http://metadb.riken.jp/0003858IC3HC57BL6C57BL6JTgLrrk26Yue0TgLrrk26Yue
• decreased neurotransmitter release_Tg(Lrrk2*G2019S)2Yue/0
  http://metadb.riken.jp/0003990IC3HC57BL6C57BL6JTgLrrk2G2019S2Yue0TgLrrk2G2019S2Yue
• tau protein deposits_Tg(Lrrk2)6Yue/0
  http://metadb.riken.jp/0004250IC3HC57BL6C57BL6JTgLrrk26Yue0TgLrrk26Yue
• abnormal locomotor coordination_Tg(Lrrk2*G2019S)2Yue/0
  http://metadb.riken.jp/0003312IC3HC57BL6C57BL6JTgLrrk2G2019S2Yue0TgLrrk2G2019S2Yue
• short stride length_Tg(Lrrk2*G2019S)2Yue/0
  http://metadb.riken.jp/0001407IC3HC57BL6C57BL6JTgLrrk2G2019S2Yue0TgLrrk2G2019S2Yue
• abnormal neurotransmitter uptake_Tg(Lrrk2*G2019S)2Yue/0
  http://metadb.riken.jp/0003444IC3HC57BL6C57BL6JTgLrrk2G2019S2Yue0TgLrrk2G2019S2Yue
• increased vertical activity_Tg(Lrrk2)6Yue/0
  http://metadb.riken.jp/0002574IC3HC57BL6C57BL6JTgLrrk26Yue0TgLrrk26Yue
• decreased dopamine level_Tg(Lrrk2*G2019S)2Yue/0
  http://metadb.riken.jp/0005643IC3HC57BL6C57BL6JTgLrrk2G2019S2Yue0TgLrrk2G2019S2Yue
• increased neurotransmitter release_Tg(Lrrk2)6Yue/0
  http://metadb.riken.jp/0008921IC3HC57BL6C57BL6JTgLrrk26Yue0TgLrrk26Yue
• hyperactivity_Tg(Lrrk2)6Yue/0
  http://metadb.riken.jp/0001399IC3HC57BL6C57BL6JTgLrrk26Yue0TgLrrk26Yue
• long stride length_Tg(Lrrk2)6Yue/0
  http://metadb.riken.jp/0010540IC3HC57BL6C57BL6JTgLrrk26Yue0TgLrrk26Yue

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD02718
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02718