Hellevi. Peltoketo, et.al., Female mice expressing constitutively active mutants of FSH receptor present with a phenotype of premature follicle depletion and estrogen excess., Endocrinology, 2010, 151

http://rdf.ncbi.nlm.nih.gov/pubmed/20172968

Hellevi. Peltoketo, et.al., Female mice expressing constitutively active mutants of FSH receptor present with a phenotype of premature follicle depletion and estrogen excess., Endocrinology, 2010, 151

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Fshr<tm1Hht>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4456197
• Tg(AMH-Fshr*D580H)14Hht
  http://metadb.riken.jp/db/mgi_rdf/MGI:4456199
• Tg(AMH-Fshr*D580H)#Hht
  http://metadb.riken.jp/db/mgi_rdf/MGI:4456198
• Tg(AMH-Fshr*D580Y)#Hht
  http://metadb.riken.jp/db/mgi_rdf/MGI:4456201
• Tg(AMH-Fshr)27Hht
  http://metadb.riken.jp/db/mgi_rdf/MGI:4456202

class

http://purl.org/net/cito/citesAsAuthority

• Fshr<tm1Hht>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4456197
• Tg(AMH-Fshr*D580H)14Hht
  http://metadb.riken.jp/db/mgi_rdf/MGI:4456199
• Tg(AMH-Fshr*D580H)#Hht
  http://metadb.riken.jp/db/mgi_rdf/MGI:4456198
• Tg(AMH-Fshr*D580Y)#Hht
  http://metadb.riken.jp/db/mgi_rdf/MGI:4456201
• Tg(AMH-Fshr)27Hht
  http://metadb.riken.jp/db/mgi_rdf/MGI:4456202

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal estrous cycle_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0001927IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• decreased circulating luteinizing hormone level_Tg(AMH-Fshr*D580H)14Hht/0
  http://metadb.riken.jp/0002773IFVBNTgAMHFshrD580H14Hht0TgAMHFshrD580H14Hht
• increased pituitary gland weight_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0008939IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• female infertility_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0001926IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• increased ovarian teratoma incidence_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0009442IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• increased ovarian teratoma incidence_Tg(AMH-Fshr*D580Y)#Hht/0
  http://metadb.riken.jp/0009442IFVBNTgAMHFshrD580YHht0TgAMHFshrD580YHht
• increased litter size_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0001934IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• abnormal mammary gland morphology_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0000627IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• ovary hemorrhage_Tg(AMH-Fshr*D580Y)#Hht/0
  http://metadb.riken.jp/0004834IFVBNTgAMHFshrD580YHht0TgAMHFshrD580YHht
• ovary hemorrhage_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0004834IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• increased circulating prolactin level_Tg(AMH-Fshr*D580H)14Hht/0
  http://metadb.riken.jp/0005124IFVBNTgAMHFshrD580H14Hht0TgAMHFshrD580H14Hht
• decreased luteinizing hormone level_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0005132IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• increased cell proliferation_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0000351IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• abnormal proestrus_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0009013IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• absent estrous cycle_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0009009IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• reduced female fertility_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0001923IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• increased ovarian teratoma incidence_Tg(AMH-Fshr)27Hht/0
  http://metadb.riken.jp/0009442IFVBNTgAMHFshr27Hht0TgAMHFshr27Hht
• increased prolactinoma incidence_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0003505IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• decreased circulating follicle stimulating hormone level_Tg(AMH-Fshr*D580H)14Hht/0
  http://metadb.riken.jp/0002790IFVBNTgAMHFshrD580H14Hht0TgAMHFshrD580H14Hht
• abnormal granulosa cell morphology_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0008868IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• abnormal ovary morphology_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0001126IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• abnormal ovarian follicle number_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0008871IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• abnormal adrenal gland morphology_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0000639IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• ovary hemorrhage_Fshr<tm1Hht>/Fshr<tm1Hht>
  http://metadb.riken.jp/0004834I129S7SvEvBrdFshrtm1HhtFshrtm1HhtFshrtm1Hht
• ovary hemorrhage_Fshr<tm1Hht>/Fshr<+>
  http://metadb.riken.jp/0004834I129S7SvEvBrdFshrtm1HhtFshrFshrtm1HhtFshr
• increased circulating estradiol level_Tg(AMH-Fshr*D580H)14Hht/0
  http://metadb.riken.jp/0005182IFVBNTgAMHFshrD580H14Hht0TgAMHFshrD580H14Hht
• increased prolactin level_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0005139IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• absent estrus_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0009021IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• abnormal ovulation_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0001928IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• abnormal fertility/fecundity_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0002161IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• ovary hemorrhage_Tg(AMH-Fshr)27Hht/0
  http://metadb.riken.jp/0004834IFVBNTgAMHFshr27Hht0TgAMHFshr27Hht
• pituitary gland hyperplasia_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0000635IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht
• increased ovarian carcinoma incidence_Tg(AMH-Fshr*D580H)#Hht/0
  http://metadb.riken.jp/0003579IFVBNTgAMHFshrD580HHht0TgAMHFshrD580HHht

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD40893
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD40893