Sheng. Xia, et.al., Polycystin-dependent fluid flow sensing targets histone deacetylase 5 to prevent the development of renal cysts., Development (Cambridge, England), 2010, 137

http://rdf.ncbi.nlm.nih.gov/pubmed/20181743

Sheng. Xia, et.al., Polycystin-dependent fluid flow sensing targets histone deacetylase 5 to prevent the development of renal cysts., Development (Cambridge, England), 2010, 137

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• lethality throughout fetal growth and development, complete penetrance_Hdac5<tm1Eno>/Hdac5<tm1Eno>,Pkd2<tm2Som>/Pkd2<tm2Som>
  http://metadb.riken.jp/0011099I129Sv129S2SvPasC57BL6SJLHdac5tm1EnoHdac5tm1EnoPkd2tm2SomPkd2tm2SomPkd2tm2SomHdac5tm1Eno
• increased kidney cell proliferation_Mtss1<Gt(RRI034)Byg>/Mtss1<Gt(RRI034)Byg>
  http://metadb.riken.jp/0011440I129P2OlaHsdC57BL6Mtss1GtRRI034BygMtss1GtRRI034BygMtss1GtRRI034Byg
• increased kidney cell proliferation_Mef2c<tm1Jjs>/Mef2c<tm1Jjs>,Tg(Slc5a2-cre)1Tauc/0
  http://metadb.riken.jp/0011440I129S6SvEvTacC57BL6DBA2Mef2ctm1JjsMef2ctm1JjsTgSlc5a2cre1Tauc0TgSlc5a2cre1TaucMef2ctm1Jjs
• kidney cysts_Hdac5<tm1Eno>/Hdac5<+>,Pkd2<tm2Som>/Pkd2<tm2Som>
  http://metadb.riken.jp/0003675I129Sv129S2SvPasC57BL6SJLHdac5tm1EnoHdac5Pkd2tm2SomPkd2tm2SomPkd2tm2SomHdac5tm1EnoHdac5
• kidney cysts_Pkd2<tm2Som>/Pkd2<tm2Som>
  http://metadb.riken.jp/0003675I129Sv129S2SvPasC57BL6SJLPkd2tm2SomPkd2tm2SomPkd2tm2Som
• dilated renal tubules_Mef2c<tm1Jjs>/Mef2c<tm1Jjs>,Tg(Slc5a2-cre)1Tauc/0
  http://metadb.riken.jp/0002705I129S6SvEvTacC57BL6DBA2Mef2ctm1JjsMef2ctm1JjsTgSlc5a2cre1Tauc0TgSlc5a2cre1TaucMef2ctm1Jjs
• dilated proximal convoluted tubules_Mef2c<tm1Jjs>/Mef2c<tm1Jjs>,Tg(Slc5a2-cre)1Tauc/0
  http://metadb.riken.jp/0009050I129S6SvEvTacC57BL6DBA2Mef2ctm1JjsMef2ctm1JjsTgSlc5a2cre1Tauc0TgSlc5a2cre1TaucMef2ctm1Jjs
• dilated distal convoluted tubules_Mef2c<tm1Jjs>/Mef2c<tm1Jjs>,Tg(Slc5a2-cre)1Tauc/0
  http://metadb.riken.jp/0009051I129S6SvEvTacC57BL6DBA2Mef2ctm1JjsMef2ctm1JjsTgSlc5a2cre1Tauc0TgSlc5a2cre1TaucMef2ctm1Jjs
• kidney cortex cysts_Mef2c<tm1Jjs>/Mef2c<tm1Jjs>,Tg(Slc5a2-cre)1Tauc/0
  http://metadb.riken.jp/0000522I129S6SvEvTacC57BL6DBA2Mef2ctm1JjsMef2ctm1JjsTgSlc5a2cre1Tauc0TgSlc5a2cre1TaucMef2ctm1Jjs
• lethality throughout fetal growth and development, complete penetrance_Pkd2<tm2Som>/Pkd2<tm2Som>
  http://metadb.riken.jp/0011099I129Sv129S2SvPasC57BL6SJLPkd2tm2SomPkd2tm2SomPkd2tm2Som
• polycystic kidney_Mtss1<Gt(RRI034)Byg>/Mtss1<Gt(RRI034)Byg>
  http://metadb.riken.jp/0008528I129P2OlaHsdC57BL6Mtss1GtRRI034BygMtss1GtRRI034BygMtss1GtRRI034Byg

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD06762
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD06762