Margareta T. Wilhelm, et.al., Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway., Genes & development, 2010, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/20194434

Margareta T. Wilhelm, et.al., Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway., Genes & development, 2010, 24

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Trp73<tm2Mak>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4442798

class

http://purl.org/net/cito/citesAsAuthority

• Trp73<tm2Mak>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4442798

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased neuron number_Trp73<tm2Mak>/Trp73<tm2Mak>
  http://metadb.riken.jp/0008948EB6129P2Trp73tm2MakorI129P2OlaHsdC57BL6JTrp73tm2MakTrp73tm2MakTrp73tm2Mak
• increased sensitivity to induced cell death_Trp73<tm2Mak>/Trp73<tm2Mak>
  http://metadb.riken.jp/0008943EB6129P2Trp73tm2MakorI129P2OlaHsdC57BL6JTrp73tm2MakTrp73tm2MakTrp73tm2Mak
• increased thymocyte apoptosis_Trp73<tm2Mak>/Trp73<tm2Mak>
  http://metadb.riken.jp/0009541EB6129P2Trp73tm2MakorI129P2OlaHsdC57BL6JTrp73tm2MakTrp73tm2MakTrp73tm2Mak
• increased cellular sensitivity to gamma-irradiation_Trp73<tm2Mak>/Trp73<tm2Mak>
  http://metadb.riken.jp/0002007EB6129P2Trp73tm2MakorI129P2OlaHsdC57BL6JTrp73tm2MakTrp73tm2MakTrp73tm2Mak
• decreased cellular sensitivity to gamma-irradiation_Trp53<tm1Brd>/Trp53<tm1Brd>,Trp73<tm2Mak>/Trp73<tm2Mak>
  http://metadb.riken.jp/0003207I129P2OlaHsd129S7SvEvBrdC57BL6JTrp53tm1BrdTrp53tm1BrdTrp73tm2MakTrp73tm2MakTrp73tm2MakTrp53tm1Brd
• abnormal cerebral cortex morphology_Trp73<tm2Mak>/Trp73<tm2Mak>
  http://metadb.riken.jp/0000788EB6129P2Trp73tm2MakorI129P2OlaHsdC57BL6JTrp73tm2MakTrp73tm2MakTrp73tm2Mak
• neurodegeneration_Trp73<tm2Mak>/Trp73<tm2Mak>
  http://metadb.riken.jp/0002229EB6129P2Trp73tm2MakorI129P2OlaHsdC57BL6JTrp73tm2MakTrp73tm2MakTrp73tm2Mak
• decreased cellular sensitivity to gamma-irradiation_Atm<tm1Pmc>/Atm<tm1Pmc>,Trp73<tm2Mak>/Trp73<tm2Mak>
  http://metadb.riken.jp/0003207I129P2OlaHsdC57BL6JAtmtm1PmcAtmtm1PmcTrp73tm2MakTrp73tm2MakTrp73tm2MakAtmtm1Pmc
• decreased thymocyte apoptosis_Trp53<tm1Brd>/Trp53<tm1Brd>,Trp73<tm2Mak>/Trp73<tm2Mak>
  http://metadb.riken.jp/0009542I129P2OlaHsd129S7SvEvBrdC57BL6JTrp53tm1BrdTrp53tm1BrdTrp73tm2MakTrp73tm2MakTrp73tm2MakTrp53tm1Brd
• increased physiological sensitivity to xenobiotic_Trp73<tm2Mak>/Trp73<tm2Mak>
  http://metadb.riken.jp/0008873EB6129P2Trp73tm2MakorI129P2OlaHsdC57BL6JTrp73tm2MakTrp73tm2MakTrp73tm2Mak
• decreased thymocyte apoptosis_Atm<tm1Pmc>/Atm<tm1Pmc>,Trp73<tm2Mak>/Trp73<tm2Mak>
  http://metadb.riken.jp/0009542I129P2OlaHsdC57BL6JAtmtm1PmcAtmtm1PmcTrp73tm2MakTrp73tm2MakTrp73tm2MakAtmtm1Pmc
• prenatal lethality, incomplete penetrance_Trp73<tm2Mak>/Trp73<tm2Mak>
  http://metadb.riken.jp/0011101EB6129P2Trp73tm2MakorI129P2OlaHsdC57BL6JTrp73tm2MakTrp73tm2MakTrp73tm2Mak