Jingxuan. Yang, et.al., Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis., The Journal of cell biology, 2010, 188

http://rdf.ncbi.nlm.nih.gov/pubmed/20308431

Jingxuan. Yang, et.al., Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis., The Journal of cell biology, 2010, 188

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• absent sebaceous gland_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0000648I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• skin fibrosis_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0009932I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• abnormal skin adnexa morphology_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0010678I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• no abnormal phenotype detected_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0002169IC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirTgKRT5cre5132Jlj0TgKRT5cre5132JljFgfr1tm1Upir
• dry skin_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0003853I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• reduced male fertility_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0001922I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• decreased body size_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0001265I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• increased keratinocyte proliferation_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0009583I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• increased IgE level_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0002497I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• decreased sebaceous gland number_Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0013192I129X1SvJC57BL6C57BL6JDBA2JFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0TgKRT5cre5132JljFgfr2tm1Dor
• skin inflammation_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0004947I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• abnormal skin adnexa morphology_Fgfr1<tm1Swnr>/Fgfr1<tm1Swnr>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0010678I129S7SvEvBrd129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1SwnrFgfr1tm1SwnrFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr1tm1SwnrFgfr2tm1DorTgKRT5cre5132Jlj
• small hair follicles_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0000380I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• alopecia_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0000414I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• acanthosis_Fgfr1<tm1Swnr>/Fgfr1<tm1Swnr>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0001874I129S7SvEvBrd129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1SwnrFgfr1tm1SwnrFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr1tm1SwnrFgfr2tm1DorTgKRT5cre5132Jlj
• absent hair follicles_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0000378I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• acanthosis_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0001874I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• polydipsia_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0001426I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• progressive hair loss_Fgfr1<tm1Swnr>/Fgfr1<tm1Swnr>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0009004I129S7SvEvBrd129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1SwnrFgfr1tm1SwnrFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr1tm1SwnrFgfr2tm1DorTgKRT5cre5132Jlj
• impaired skin barrier function_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0002796I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• progressive hair loss_Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0009004I129X1SvJC57BL6C57BL6JDBA2JFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0TgKRT5cre5132JljFgfr2tm1Dor
• abnormal hair follicle morphology_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0000377I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• abnormal epidermis stratum granulosum morphology_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0001239I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• female infertility_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0001926I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• abnormal hair cycle_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0000427I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• abnormal skin appearance_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0009931I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• progressive hair loss_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0009004I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• decreased body size_Fgfr1<tm1Swnr>/Fgfr1<tm1Swnr>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0001265I129S7SvEvBrd129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1SwnrFgfr1tm1SwnrFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr1tm1SwnrFgfr2tm1DorTgKRT5cre5132Jlj
• increased IgG2a level_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0008500I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• increased IgG1 level_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0008499I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj
• abnormal coat/ hair morphology_Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0000367I129X1SvJC57BL6C57BL6JDBA2JFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0TgKRT5cre5132JljFgfr2tm1Dor
• abnormal epidermal layer morphology_Fgfr1<tm1Upir>/Fgfr1<tm1Upir>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Tg(KRT5-cre)5132Jlj/0
  http://metadb.riken.jp/0001216I129X1SvJC57BL6C57BL6JDBA2JFgfr1tm1UpirFgfr1tm1UpirFgfr2tm1DorFgfr2tm1DorTgKRT5cre5132Jlj0Fgfr2tm1DorFgfr1tm1UpirTgKRT5cre5132Jlj