R Sathish. Srinivasan, et.al., The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells., Genes & development, 2010, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/20360386

R Sathish. Srinivasan, et.al., The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells., Genes & development, 2010, 24

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Prox1<tm5(GFP/cre)Gco>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4441289
• Prox1<tm4.1Gco>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4441290

class

http://purl.org/net/cito/citesAsAuthority

• Prox1<tm5(GFP/cre)Gco>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4441289
• Prox1<tm4.1Gco>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4441290

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased survivor rate_Prox1<tm5(GFP/cre)Gco>/Prox1<+>
  http://metadb.riken.jp/0008770I129S1SvNMRIProx1tm5GFPcreGcoProx1Prox1Prox1tm5GFPcreGco
• decreased lymphatic vessel endothelial cell number_Prox1<tm1Gco>/Prox1<tm5(GFP/cre)Gco>
  http://metadb.riken.jp/0010198I129S1Sv129X1SvJNMRIProx1tm1GcoProx1tm5GFPcreGcoProx1tm1GcoProx1tm5GFPcreGco
• abnormal lymphatic vessel morphology_Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Nr2f2<tm2.1Tsa>/Nr2f2<tm2.1Tsa>,Prox1<tm3(cre/ERT2)Gco>/Prox1<+>
  http://metadb.riken.jp/0001879I129S1Sv129S4SvJaeSor129S7SvEvBrdC57BL6GtROSA26Sortm1SorGtROSA26SorNr2f2tm21TsaNr2f2tm21TsaProx1tm3creERT2GcoProx1GtROSA26SorGtROSA26Sortm1SorProx1tm3creERT2GcoProx1Nr2f2tm21Tsa
• edema_Prox1<tm4.1Gco>/Prox1<tm4.1Gco>
  http://metadb.riken.jp/0001785I129S1SvC57BL10CBACaProx1tm41GcoProx1tm41GcoProx1tm41Gco
• decreased lymphatic vessel endothelial cell number_Nr2f2<tm2.1Tsa>/Nr2f2<tm2.1Tsa>,Rbpj<tm1Hon>/Rbpj<tm1Hon>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0010198I129S1Sv129S7SvEvBrdC57BL6SJLNr2f2tm21TsaNr2f2tm21TsaRbpjtm1HonRbpjtm1HonTgTekcre1Ywa0TgTekcre1YwaRbpjtm1HonNr2f2tm21Tsa
• embryonic lethality, incomplete penetrance_Rbpj<tm1Hon>/Rbpj<tm1Hon>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0011102I129S7SvEvBrdC57BL6SJLRbpjtm1HonRbpjtm1HonTgTekcre1Ywa0TgTekcre1YwaRbpjtm1Hon
• edema_Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Nr2f2<tm2.1Tsa>/Nr2f2<tm2.1Tsa>,Prox1<tm3(cre/ERT2)Gco>/Prox1<+>
  http://metadb.riken.jp/0001785I129S1Sv129S4SvJaeSor129S7SvEvBrdC57BL6GtROSA26Sortm1SorGtROSA26SorNr2f2tm21TsaNr2f2tm21TsaProx1tm3creERT2GcoProx1GtROSA26SorGtROSA26Sortm1SorProx1tm3creERT2GcoProx1Nr2f2tm21Tsa
• decreased lymphatic vessel endothelial cell number_Prox1<tm4.1Gco>/Prox1<tm4.1Gco>
  http://metadb.riken.jp/0010198I129S1SvC57BL10CBACaProx1tm41GcoProx1tm41GcoProx1tm41Gco
• decreased lymphatic vessel endothelial cell number_Nr2f2<tm2.1Tsa>/Nr2f2<tm2.1Tsa>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0010198I129S1Sv129S7SvEvBrdC57BL6SJLNr2f2tm21TsaNr2f2tm21TsaTgTekcre1Ywa0Nr2f2tm21TsaTgTekcre1Ywa
• embryonic lethality, incomplete penetrance_Nr2f2<tm2.1Tsa>/Nr2f2<tm2.1Tsa>,Rbpj<tm1Hon>/Rbpj<tm1Hon>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0011102I129S1Sv129S7SvEvBrdC57BL6SJLNr2f2tm21TsaNr2f2tm21TsaRbpjtm1HonRbpjtm1HonTgTekcre1Ywa0TgTekcre1YwaRbpjtm1HonNr2f2tm21Tsa

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD12239
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12239