Kenneth H. Gabbay, et.al., Ascorbate synthesis pathway: dual role of ascorbate in bone homeostasis., The Journal of biological chemistry, 2010, 285

http://rdf.ncbi.nlm.nih.gov/pubmed/20410296

Kenneth H. Gabbay, et.al., Ascorbate synthesis pathway: dual role of ascorbate in bone homeostasis., The Journal of biological chemistry, 2010, 285

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Akr1b3<tm1.1Kgab>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5008171

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• osteoporosis_Akr1a1<Gt(OST222400)Lex>/Akr1a1<Gt(OST222400)Lex>
  http://metadb.riken.jp/0000066B6129S5Akr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400Lex
• abnormal vitamin C level_Akr1b3<tm1.1Kgab>/Akr1b3<tm1.1Kgab>
  http://metadb.riken.jp/0011229B6CgAkr1b3tm11KgabAkr1b3tm11KgabAkr1b3tm11KgabAkr1b3tm11Kgab
• abnormal vitamin C level_Gulo<tm1Mae>/Gulo<tm1Mae>
  http://metadb.riken.jp/0011229IC57BL6Gulotm1MaeGulotm1MaeGulotm1Mae
• decreased osteoblast cell number_Akr1a1<Gt(OST222400)Lex>/Akr1a1<Gt(OST222400)Lex>
  http://metadb.riken.jp/0004989B6129S5Akr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400Lex
• decreased compact bone thickness_Akr1a1<Gt(OST222400)Lex>/Akr1a1<Gt(OST222400)Lex>
  http://metadb.riken.jp/0000135B6129S5Akr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400Lex
• decreased trabecular bone thickness_Akr1a1<Gt(OST222400)Lex>/Akr1a1<Gt(OST222400)Lex>
  http://metadb.riken.jp/0009346B6129S5Akr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400Lex
• premature death_Gulo<tm1Mae>/Gulo<tm1Mae>
  http://metadb.riken.jp/0002083IC57BL6Gulotm1MaeGulotm1MaeGulotm1Mae
• premature death_Akr1a1<Gt(OST222400)Lex>/Akr1a1<Gt(OST222400)Lex>,Akr1b3<tm1.1Kgab>/Akr1b3<tm1.1Kgab>
  http://metadb.riken.jp/0002083B6CgAkr1a1GtOST222400LexAkr1b3tm11KgabAkr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1b3tm11KgabAkr1b3tm11KgabAkr1a1GtOST222400LexAkr1b3tm11Kgab
• abnormal osteoblast physiology_Akr1a1<Gt(OST222400)Lex>/Akr1a1<Gt(OST222400)Lex>
  http://metadb.riken.jp/0005006B6129S5Akr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400Lex
• decreased bone trabecula number_Akr1a1<Gt(OST222400)Lex>/Akr1a1<Gt(OST222400)Lex>
  http://metadb.riken.jp/0010869B6129S5Akr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400Lex
• decreased bone volume_Akr1a1<Gt(OST222400)Lex>/Akr1a1<Gt(OST222400)Lex>
  http://metadb.riken.jp/0010876B6129S5Akr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400Lex
• abnormal turbinate morphology_Akr1a1<Gt(OST222400)Lex>/Akr1a1<Gt(OST222400)Lex>
  http://metadb.riken.jp/0002244B6129S5Akr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400Lex
• abnormal osteoblast differentiation_Akr1a1<Gt(OST222400)Lex>/Akr1a1<Gt(OST222400)Lex>
  http://metadb.riken.jp/0008395B6129S5Akr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400Lex
• increased osteoclast cell number_Akr1a1<Gt(OST222400)Lex>/Akr1a1<Gt(OST222400)Lex>
  http://metadb.riken.jp/0004984B6129S5Akr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400Lex
• aminoaciduria_Akr1a1<Gt(OST222400)Lex>/Akr1a1<Gt(OST222400)Lex>
  http://metadb.riken.jp/0003311B6129S5Akr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400Lex
• joint swelling_Gulo<tm1Mae>/Gulo<tm1Mae>
  http://metadb.riken.jp/0002936IC57BL6Gulotm1MaeGulotm1MaeGulotm1Mae
• fragile skeleton_Akr1a1<Gt(OST222400)Lex>/Akr1a1<Gt(OST222400)Lex>
  http://metadb.riken.jp/0000061B6129S5Akr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400Lex
• joint swelling_Akr1a1<Gt(OST222400)Lex>/Akr1a1<Gt(OST222400)Lex>,Akr1b3<tm1.1Kgab>/Akr1b3<tm1.1Kgab>
  http://metadb.riken.jp/0002936B6CgAkr1a1GtOST222400LexAkr1b3tm11KgabAkr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1b3tm11KgabAkr1b3tm11KgabAkr1a1GtOST222400LexAkr1b3tm11Kgab
• female infertility_Akr1a1<Gt(OST222400)Lex>/Akr1a1<Gt(OST222400)Lex>
  http://metadb.riken.jp/0001926B6129S5Akr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400Lex
• abnormal osteoclast physiology_Akr1a1<Gt(OST222400)Lex>/Akr1a1<Gt(OST222400)Lex>
  http://metadb.riken.jp/0001541B6129S5Akr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400Lex
• abnormal trabecular bone morphology_Akr1a1<Gt(OST222400)Lex>/Akr1a1<Gt(OST222400)Lex>
  http://metadb.riken.jp/0000130B6129S5Akr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400Lex
• abnormal vitamin C level_Akr1a1<Gt(OST222400)Lex>/Akr1a1<Gt(OST222400)Lex>
  http://metadb.riken.jp/0011229B6129S5Akr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400LexAkr1a1GtOST222400Lex

class

http://purl.org/net/cito/citesAsAuthority

• Akr1b3<tm1.1Kgab>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5008171

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD09417
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD09417