Brandon S J. Davies, et.al., An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria., Human molecular genetics, 2010, 19

http://rdf.ncbi.nlm.nih.gov/pubmed/20421363

Brandon S J. Davies, et.al., An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria., Human molecular genetics, 2010, 19

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Lmna<tm6Lgf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4457608
• Lmna<tm5Lgf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4457607

class

http://purl.org/net/cito/citesAsAuthority

• Lmna<tm6Lgf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4457608
• Lmna<tm5Lgf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4457607

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased body weight_Lmna<tm6Lgf>/Lmna<tm6Lgf>,Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>
  http://metadb.riken.jp/0001262I129P2OlaHsd129S4SvJaeC57BL6Lmnatm6LgfLmnatm6LgfZmpste24tm1SgyZmpste24tm1SgyZmpste24tm1SgyLmnatm6Lgf
• premature death_Lmna<tm6Lgf>/Lmna<+>,Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>
  http://metadb.riken.jp/0002083I129P2OlaHsd129S4SvJaeC57BL6Lmnatm6LgfLmnaZmpste24tm1SgyZmpste24tm1SgyLmnatm6LgfZmpste24tm1SgyLmna
• decreased ventricle muscle contractility_Lmna<tm5Lgf>/Lmna<tm5Lgf>
  http://metadb.riken.jp/0005598I129P2OlaHsdC57BL6Lmnatm5LgfLmnatm5LgfLmnatm5Lgf
• decreased survivor rate_Lmna<tm5Lgf>/Lmna<tm5Lgf>
  http://metadb.riken.jp/0008770I129P2OlaHsdC57BL6Lmnatm5LgfLmnatm5LgfLmnatm5Lgf
• decreased body weight_Lmna<tm5Lgf>/Lmna<tm5Lgf>
  http://metadb.riken.jp/0001262I129P2OlaHsdC57BL6Lmnatm5LgfLmnatm5LgfLmnatm5Lgf
• premature death_Lmna<tm5Lgf>/Lmna<tm5Lgf>
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6Lmnatm5LgfLmnatm5LgfLmnatm5Lgf
• decreased body weight_Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>
  http://metadb.riken.jp/0001262I129S4SvJaeZmpste24tm1SgyZmpste24tm1SgyZmpste24tm1Sgy
• rib fractures_Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>
  http://metadb.riken.jp/0004675I129S4SvJaeZmpste24tm1SgyZmpste24tm1SgyZmpste24tm1Sgy
• decreased body weight_Lmna<tm6Lgf>/Lmna<+>,Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>
  http://metadb.riken.jp/0001262I129P2OlaHsd129S4SvJaeC57BL6Lmnatm6LgfLmnaZmpste24tm1SgyZmpste24tm1SgyLmnatm6LgfZmpste24tm1SgyLmna
• premature death_Lmna<tm6Lgf>/Lmna<tm6Lgf>,Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>
  http://metadb.riken.jp/0002083I129P2OlaHsd129S4SvJaeC57BL6Lmnatm6LgfLmnatm6LgfZmpste24tm1SgyZmpste24tm1SgyZmpste24tm1SgyLmnatm6Lgf
• decreased body weight_Lmna<tm6Lgf>/Lmna<tm6Lgf>
  http://metadb.riken.jp/0001262I129P2OlaHsdC57BL6Lmnatm6LgfLmnatm6LgfLmnatm6Lgf
• cardiac fibrosis_Lmna<tm5Lgf>/Lmna<tm5Lgf>
  http://metadb.riken.jp/0003141I129P2OlaHsdC57BL6Lmnatm5LgfLmnatm5LgfLmnatm5Lgf
• decreased survivor rate_Lmna<tm6Lgf>/Lmna<tm6Lgf>,Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>
  http://metadb.riken.jp/0008770I129P2OlaHsd129S4SvJaeC57BL6Lmnatm6LgfLmnatm6LgfZmpste24tm1SgyZmpste24tm1SgyZmpste24tm1SgyLmnatm6Lgf
• decreased survivor rate_Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>
  http://metadb.riken.jp/0008770I129S4SvJaeZmpste24tm1SgyZmpste24tm1SgyZmpste24tm1Sgy
• dilated cardiomyopathy_Lmna<tm5Lgf>/Lmna<tm5Lgf>
  http://metadb.riken.jp/0002795I129P2OlaHsdC57BL6Lmnatm5LgfLmnatm5LgfLmnatm5Lgf
• abnormal cell nucleus morphology_Lmna<tm5Lgf>/Lmna<tm5Lgf>
  http://metadb.riken.jp/0003111I129P2OlaHsdC57BL6Lmnatm5LgfLmnatm5LgfLmnatm5Lgf
• abnormal skeleton morphology_Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>
  http://metadb.riken.jp/0005508I129S4SvJaeZmpste24tm1SgyZmpste24tm1SgyZmpste24tm1Sgy
• decreased survivor rate_Lmna<tm6Lgf>/Lmna<+>,Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>
  http://metadb.riken.jp/0008770I129P2OlaHsd129S4SvJaeC57BL6Lmnatm6LgfLmnaZmpste24tm1SgyZmpste24tm1SgyLmnatm6LgfZmpste24tm1SgyLmna
• premature death_Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>
  http://metadb.riken.jp/0002083I129S4SvJaeZmpste24tm1SgyZmpste24tm1SgyZmpste24tm1Sgy
• dilated heart left ventricle_Lmna<tm5Lgf>/Lmna<tm5Lgf>
  http://metadb.riken.jp/0002753I129P2OlaHsdC57BL6Lmnatm5LgfLmnatm5LgfLmnatm5Lgf
• aphagia_Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>
  http://metadb.riken.jp/0001438I129S4SvJaeZmpste24tm1SgyZmpste24tm1SgyZmpste24tm1Sgy

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD23003
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD23003