Tao. Yu, et.al., A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions., Human molecular genetics, 2010, 19

http://rdf.ncbi.nlm.nih.gov/pubmed/20442137

Tao. Yu, et.al., A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions., Human molecular genetics, 2010, 19

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Dp(10Prmt2-Pdxk)2Yey
  http://metadb.riken.jp/db/mgi_rdf/MGI:4461400
• Dp(17Abcg1-Rrp1b)3Yey
  http://metadb.riken.jp/db/mgi_rdf/MGI:4461399

class

http://purl.org/net/cito/citesAsAuthority

• Dp(10Prmt2-Pdxk)2Yey
  http://metadb.riken.jp/db/mgi_rdf/MGI:4461400
• Dp(17Abcg1-Rrp1b)3Yey
  http://metadb.riken.jp/db/mgi_rdf/MGI:4461399

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• neonatal lethality, incomplete penetrance_Dp(10Prmt2-Pdxk)2Yey/0,Dp(16Lipi-Zbtb21)1Yey/0,Dp(17Abcg1-Rrp1b)3Yey/0
  http://metadb.riken.jp/0011088B6129S7Dp10Prmt2Pdxk2YeyDp16LipiZbtb211YeyDp17Abcg1Rrp1b3YeyDp10Prmt2Pdxk2Yey0Dp16LipiZbtb211Yey0Dp17Abcg1Rrp1b3Yey0Dp10Prmt2Pdxk2YeyDp17Abcg1Rrp1b3YeyDp16LipiZbtb211Yey
• cerebral aqueductal stenosis_Dp(10Prmt2-Pdxk)2Yey/0,Dp(16Lipi-Zbtb21)1Yey/0,Dp(17Abcg1-Rrp1b)3Yey/0
  http://metadb.riken.jp/0002958B6129S7Dp10Prmt2Pdxk2YeyDp16LipiZbtb211YeyDp17Abcg1Rrp1b3YeyDp10Prmt2Pdxk2Yey0Dp16LipiZbtb211Yey0Dp17Abcg1Rrp1b3Yey0Dp10Prmt2Pdxk2YeyDp17Abcg1Rrp1b3YeyDp16LipiZbtb211Yey
• reduced long term potentiation_Dp(10Prmt2-Pdxk)2Yey/0,Dp(16Lipi-Zbtb21)1Yey/0,Dp(17Abcg1-Rrp1b)3Yey/0
  http://metadb.riken.jp/0001473B6129S7Dp10Prmt2Pdxk2YeyDp16LipiZbtb211YeyDp17Abcg1Rrp1b3YeyDp10Prmt2Pdxk2Yey0Dp16LipiZbtb211Yey0Dp17Abcg1Rrp1b3Yey0Dp10Prmt2Pdxk2YeyDp17Abcg1Rrp1b3YeyDp16LipiZbtb211Yey
• neonatal lethality_Dp(10Prmt2-Pdxk)2Yey/0,Dp(16Lipi-Zbtb21)1Yey/0
  http://metadb.riken.jp/0002058B6129S7Dp10Prmt2Pdxk2YeyDp16LipiZbtb211YeyDp10Prmt2Pdxk2Yey0Dp16LipiZbtb211Yey0Dp16LipiZbtb211YeyDp10Prmt2Pdxk2Yey
• impaired swimming_Dp(10Prmt2-Pdxk)2Yey/0,Dp(16Lipi-Zbtb21)1Yey/0,Dp(17Abcg1-Rrp1b)3Yey/0
  http://metadb.riken.jp/0001522B6129S7Dp10Prmt2Pdxk2YeyDp16LipiZbtb211YeyDp17Abcg1Rrp1b3YeyDp10Prmt2Pdxk2Yey0Dp16LipiZbtb211Yey0Dp17Abcg1Rrp1b3Yey0Dp10Prmt2Pdxk2YeyDp17Abcg1Rrp1b3YeyDp16LipiZbtb211Yey
• decreased survivor rate_Dp(10Prmt2-Pdxk)2Yey/0,Dp(16Lipi-Zbtb21)1Yey/0,Dp(17Abcg1-Rrp1b)3Yey/0
  http://metadb.riken.jp/0008770B6129S7Dp10Prmt2Pdxk2YeyDp16LipiZbtb211YeyDp17Abcg1Rrp1b3YeyDp10Prmt2Pdxk2Yey0Dp16LipiZbtb211Yey0Dp17Abcg1Rrp1b3Yey0Dp10Prmt2Pdxk2YeyDp17Abcg1Rrp1b3YeyDp16LipiZbtb211Yey
• abnormal heart morphology_Dp(10Prmt2-Pdxk)2Yey/0,Dp(16Lipi-Zbtb21)1Yey/0,Dp(17Abcg1-Rrp1b)3Yey/0
  http://metadb.riken.jp/0000266B6129S7Dp10Prmt2Pdxk2YeyDp16LipiZbtb211YeyDp17Abcg1Rrp1b3YeyDp10Prmt2Pdxk2Yey0Dp16LipiZbtb211Yey0Dp17Abcg1Rrp1b3Yey0Dp10Prmt2Pdxk2YeyDp17Abcg1Rrp1b3YeyDp16LipiZbtb211Yey
• decreased grip strength_Dp(10Prmt2-Pdxk)2Yey/0,Dp(16Lipi-Zbtb21)1Yey/0,Dp(17Abcg1-Rrp1b)3Yey/0
  http://metadb.riken.jp/0010053B6129S7Dp10Prmt2Pdxk2YeyDp16LipiZbtb211YeyDp17Abcg1Rrp1b3YeyDp10Prmt2Pdxk2Yey0Dp16LipiZbtb211Yey0Dp17Abcg1Rrp1b3Yey0Dp10Prmt2Pdxk2YeyDp17Abcg1Rrp1b3YeyDp16LipiZbtb211Yey
• premature death_Dp(10Prmt2-Pdxk)2Yey/0,Dp(16Lipi-Zbtb21)1Yey/0,Dp(17Abcg1-Rrp1b)3Yey/0
  http://metadb.riken.jp/0002083B6129S7Dp10Prmt2Pdxk2YeyDp16LipiZbtb211YeyDp17Abcg1Rrp1b3YeyDp10Prmt2Pdxk2Yey0Dp16LipiZbtb211Yey0Dp17Abcg1Rrp1b3Yey0Dp10Prmt2Pdxk2YeyDp17Abcg1Rrp1b3YeyDp16LipiZbtb211Yey
• obstructive hydrocephaly_Dp(10Prmt2-Pdxk)2Yey/0,Dp(16Lipi-Zbtb21)1Yey/0,Dp(17Abcg1-Rrp1b)3Yey/0
  http://metadb.riken.jp/0000917B6129S7Dp10Prmt2Pdxk2YeyDp16LipiZbtb211YeyDp17Abcg1Rrp1b3YeyDp10Prmt2Pdxk2Yey0Dp16LipiZbtb211Yey0Dp17Abcg1Rrp1b3Yey0Dp10Prmt2Pdxk2YeyDp17Abcg1Rrp1b3YeyDp16LipiZbtb211Yey
• dilated lateral ventricles_Dp(10Prmt2-Pdxk)2Yey/0,Dp(16Lipi-Zbtb21)1Yey/0,Dp(17Abcg1-Rrp1b)3Yey/0
  http://metadb.riken.jp/0000825B6129S7Dp10Prmt2Pdxk2YeyDp16LipiZbtb211YeyDp17Abcg1Rrp1b3YeyDp10Prmt2Pdxk2Yey0Dp16LipiZbtb211Yey0Dp17Abcg1Rrp1b3Yey0Dp10Prmt2Pdxk2YeyDp17Abcg1Rrp1b3YeyDp16LipiZbtb211Yey
• impaired contextual conditioning behavior_Dp(10Prmt2-Pdxk)2Yey/0,Dp(16Lipi-Zbtb21)1Yey/0,Dp(17Abcg1-Rrp1b)3Yey/0
  http://metadb.riken.jp/0009454B6129S7Dp10Prmt2Pdxk2YeyDp16LipiZbtb211YeyDp17Abcg1Rrp1b3YeyDp10Prmt2Pdxk2Yey0Dp16LipiZbtb211Yey0Dp17Abcg1Rrp1b3Yey0Dp10Prmt2Pdxk2YeyDp17Abcg1Rrp1b3YeyDp16LipiZbtb211Yey
• abnormal spatial reference memory_Dp(10Prmt2-Pdxk)2Yey/0,Dp(16Lipi-Zbtb21)1Yey/0,Dp(17Abcg1-Rrp1b)3Yey/0
  http://metadb.riken.jp/0008414B6129S7Dp10Prmt2Pdxk2YeyDp16LipiZbtb211YeyDp17Abcg1Rrp1b3YeyDp10Prmt2Pdxk2Yey0Dp16LipiZbtb211Yey0Dp17Abcg1Rrp1b3Yey0Dp10Prmt2Pdxk2YeyDp17Abcg1Rrp1b3YeyDp16LipiZbtb211Yey
• abnormal spatial learning_Dp(10Prmt2-Pdxk)2Yey/0,Dp(16Lipi-Zbtb21)1Yey/0,Dp(17Abcg1-Rrp1b)3Yey/0
  http://metadb.riken.jp/0001463B6129S7Dp10Prmt2Pdxk2YeyDp16LipiZbtb211YeyDp17Abcg1Rrp1b3YeyDp10Prmt2Pdxk2Yey0Dp16LipiZbtb211Yey0Dp17Abcg1Rrp1b3Yey0Dp10Prmt2Pdxk2YeyDp17Abcg1Rrp1b3YeyDp16LipiZbtb211Yey
• neonatal lethality_Dp(16Lipi-Zbtb21)1Yey/0,Dp(17Abcg1-Rrp1b)3Yey/0
  http://metadb.riken.jp/0002058B6129S7Dp16LipiZbtb211YeyDp17Abcg1Rrp1b3YeyDp16LipiZbtb211Yey0Dp17Abcg1Rrp1b3Yey0Dp16LipiZbtb211YeyDp17Abcg1Rrp1b3Yey