Ilenia. Bernascone, et.al., A transgenic mouse model for uromodulin-associated kidney diseases shows specific tubulo-interstitial damage, urinary concentrating defect and renal failure., Human molecular genetics, 2010, 19

http://rdf.ncbi.nlm.nih.gov/pubmed/20472742

Ilenia. Bernascone, et.al., A transgenic mouse model for uromodulin-associated kidney diseases shows specific tubulo-interstitial damage, urinary concentrating defect and renal failure., Human molecular genetics, 2010, 19

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Umod*C147W)958Lura
  http://metadb.riken.jp/db/mgi_rdf/MGI:4819096
• Tg(Umod)416Lura
  http://metadb.riken.jp/db/mgi_rdf/MGI:4819095

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Umod*C147W)958Lura
  http://metadb.riken.jp/db/mgi_rdf/MGI:4819096
• Tg(Umod)416Lura
  http://metadb.riken.jp/db/mgi_rdf/MGI:4819095

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased blood osmolality_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0008997IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• increased circulating creatinine level_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0005553IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• increased blood urea nitrogen level_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0005565IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• renal tubular necrosis_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0004154IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• kidney corticomedullary cysts_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0011308IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• polydipsia_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0001426IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• kidney inflammation_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0001859IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• kidney failure_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0003606IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• increased circulating antidiuretic hormone level_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0005610IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• abnormal renal/urinary system physiology_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0005502IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• increased urine calcium level_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0005441IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• isosthenuria_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0013305IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• polyuria_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0001762IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• dilated renal tubules_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0002705IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• decreased urine osmolality_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0002988IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• renal tubule atrophy_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0011346IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• renal interstitial fibrosis_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0003215IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• no abnormal phenotype detected_Tg(Umod)416Lura/0
  http://metadb.riken.jp/0002169IFVBTgUmod416Lura0TgUmod416Lura
• abnormal renal tubule morphology_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0002703IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• decreased urine pH_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0009350IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• abnormal kidney morphology_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0002135IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• renal cast_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0011402IFVBTgUmodC147W958Lura0TgUmodC147W958Lura
• increased kidney cell proliferation_Tg(Umod*C147W)958Lura/0
  http://metadb.riken.jp/0011440IFVBTgUmodC147W958Lura0TgUmodC147W958Lura